EN 九州大学
研究業績

Publications

原著論文

2025

  1. Q. He, J. He, P. Wen, H. Guo, M. Tanaka, S. Luo, J. Li, Y. Liu, L. Wen, C. Yao, NIR-Activatable Aza-BODIPY Nanoparticles for Photoacoustic Imaging and Synergistic NO–Photothermal Cancer Therapy, Biomater. Sci., 13, 5369-5381 (2025).
    DOI: 10.1039/D5BM00937E
  2. Y. Ohnishi, D. Setoyama, H. Miwa, N. Koitabashi, R. Ogasawara, S. Kitada, N. Matoba, T. Ayano, K. Hiramoto, R. Yasui, Y. Sugiura, T. Anada, K. Ino, H. Matsuda, T. Noma, S. Nonaka, T. Izumi, M. Kurabayashi, M. Suematsu, Y. Kunisaki, M. Yanagita, H. Imamura, M. Yamamoto, AVID mouse: A versatile platform for real-time, multiscale ATP imaging and spatial systems metabolism analysis in living mice, Cell Reports, 44(9), 116246 (2025).
    DOI: 10.1016/j.celrep.2025.116246
  3. S. Kobayashi, Y. Okazaki, M. Tanaka, Impact of Side Chain Carbonyl Group Position on Polymer Hydration, Dynamics, and Antithrombotic Activity: A Systematic Study of Structure-Property Relationships, Macromolecules, 58(16), 8821-8832 (2025).
    DOI: 10.1021/acs.macromol.5c01688
  4. K. Uchida, N. Shimokawa, R. Wakabayashi, S. Shiomoto, K. Toyofuku, N. Ogushi, M. Goto, M. Tanaka, M. Takagi, N. Kamiya, Exploring the significance of palmitoylation using an artificial protein lipidation system, RSC Chemical Biology, 6, 1483-1496 (2025).
    DOI: 10.1039/D5CB00143A
  5. K. Kitagawa, S. Kobayashi, Y. Miura, M. Tanaka, H. Ise, Targeting and Suppression of Survivin in Cancer Cells Based on the Interaction of Cell Surface Vimentin with N-Acetylglucosamine-Bearing Polymers, ACS Omega, 10(33), 37162-37175 (2025).
    DOI: 10.1021/acsomega.5c02098
  6. T. Anada, M. Kawahara, T. Shimada, R. Kuroda, H. Okamura, D. Setoyama, F. Nagatsugi, Y. Kunisaki, E. K. Nakadai, S. Kobayashi, M.Tanaka, A nucleic acid prodrug that activates mitochondrial respiration, promotes stress resilience, and prolongs lifespan, J. Am. Chem. Soc., 147(25), 22161-22175 (2025).
    DOI: 10.1021/jacs.5c06772
  7. L. Sun, Q. Pan, Y. Li, Y. Mu, Y. Cheng, Y. Feng, M. Tanaka, P. Wen, X. Liu, Semi-permeable polymer vesicle-based prooxidative and lactate-depleting nanoreactors with sustained activity against pancreatic cancer, Front. Bioeng. Biotechnol., 13, 1626927 (2025).
    DOI: 10.3389/fbioe.2025.1626927
  8. B. Fei, H. Wang, Y. Ding, N. Shao, P. Wen, Y. Cao, J. Li, M. Tanaka, Z. Wang, S. Li, Reprogramming Cellular Senescence of Hepatic Stellate Cells to Combat Liver Fibrosis by Targeted Nanodrugs, Materials Today Bio, 33, 101996 (2025).
    DOI : 10.1016/j.mtbio.2025.101996
  9. M. A. Saleh, Y. Higuchi, S. Shiomoto, T. Anada, M. Hishida, M. Tanaka, Effect of Zwitterionic Monomer Polymerization on Water Dynamics: A Molecular Dynamics Simulation Study Supported by Differential Scanning Calorimetry and Terahertz Spectroscopy, Polym. J., 57, 1127–1139 (2025).
    DOI : 10.1038/s41428-025-01066-0
  10. Y. Kawai, J. Park, R. Motokawa, R. Ikura, S. Murayama, K. Yamaoka, Y. Fujii, Y. Ikemoto, M. Tanaka, G. Matsuba, T. Kato, Y. Takashima, Effects of the Hydration States of Water Molecules on the Mechanical Properties of Dual Movable Crosslinked Polymeric Gels, ACS Appl. Polym. Mater., 7(12), 7767-7776 (2025).
    DOI : 10.1021/acsapm.5c00270
  11. P. Wen, A. Dirisala, H. Guo, X. Liu, S. Kobayashi, H. Kinoh, T. Anada, M. Tanaka, K. Kataoka, J. Li, Engineering Durable Antioxidative Nanoreactors as Synthetic Organelles for Autoregulatory Cellular Protection Against Oxidative Stress, Journal of Controlled Release, 382, 113683 (2025).
    DOI: 10.1016/j.jconrel.2025.113683
  12. M. Nakayama, T. Kanno, A. Kikuchi, Y. Tanaka, T. Anada, M. Tanaka, T. Okano, Visible-light-triggered recovery of biologically intact cells using smart fluoropolymer-nanocoated materials, Journal of Controlled Release, 382, 113653 (2025).
    DOI: 10.1016/j.jconrel.2025.113653
  13. I. S. Cho, S. Shiomoto, N. Yukawa, Y. Tanaka, K.M. Huh, M. Tanaka, The Role of Intermediate Water in Enhancing Blood and Cellular Compatibility of Chitosan-Based Biomaterials, Langmuir, 41(12), 8301–8311 (2025).
    DOI: 10.1021/acs.langmuir.5c00125
  14. K. Yokota, S. Usuda, T. Nishimura, R. Takahashi, Y. Taoka, S. Kobayashi, M. Tanaka, K. Matsumura, S. Yusa, Self-Assembly and Drug Encapsulation Properties of Biocompatible Amphiphilic Diblock Copolymers, Langmuir, 41(1), 765–773 (2025).
    DOI: 10.1021/acs.langmuir.4c04048
    2024
  15. T. Anada, M. Kawahara, T. Shimada, R. Kuroda, E. Kage-Nakadai, S. Kobayashi, M. Tanaka, A nucleic acid prodrug activates mitochondrial respiration and extends lifespan, bioRxiv (2024).
    DOI:10.1101/2024.11.16.623599
  16. S. Nishimura, N. Kurahashi, S. Shiomoto, Y. Harada, M. Tanaka, Effects of Hydration Water on Bioresponsiveness of Polymer Interfaces Revealed by Analysis of Linear and Cyclic Polymer–Grafted Substrates, Soft Matter, 2024, 20, 9454-9463 (2024).
    DOI:10.1039/D4SM00977K
  17. T. Suzuki, H. Konishi, A. Suzuki, T. Katsumata, Y. Fukuda, K. Miyamoto, T. Ise, Y. Tanaka, A. Yamamoto, P. Wen, S. Shiomoto, M. Tanaka, S. Nemoto, Role of intermediate water in reducing postsurgical intrapericardial adhesion, Surgery Today, 555, 847–856 (2025).
    DOI : 10.1007/s00595-024-02953-4
  18. B. Fei, Y. Zhao, J. Wang, P. Wen, J. Li, M. Tanaka, S. Li, Z. Wang, Leveraging Adrenergic Receptor Blockade for Enhanced Nonalcoholic Fatty Liver Disease Treatment via a Biomimetic Nanoplatform, Journal of Nanobiotechnology, 22(1), 591 (2024).
    DOI:10.1186/s12951-024-02864-z
  19. M. Najmina, R. Shimazui, S. Kobayashi, H. Takata, M. Shibata, K. Ishibashi, A. Kishimura, Y. Shiota, D. Ida, T. Shimizu, T. Ishida, Y. Katayama, M.Tanaka, T. Mori, A Stealthiness Evaluation of Main Chain Carboxybetaine Polymer Modified into Liposome, Pharmaceutics, 16(10), 1271 (2024).
    DOI:10.3390/pharmaceutics16101271 
  20. Y. Higaki, T. Masuda, S. Shiomoto, Y. Tanaka, H. Kiuchi, Y. Harada,  M. Tanaka, Pronounced Cold Crystallization and Hydrogen Bonding Distortion of Water Confined in Microphases of Double Zwitterionic Block Copolymer Aqueous Solutions, Langmuir, 40(37), 19612-19618 (2024).
    DOI:10.1021/acs.langmuir.4c02254
  21. K. Nishida, R. Ikura, K. Yamaoka, O. Urakawa, T. Konishi, T. Inoue, G. Matsuba, M. Tanaka, Y. Takashima, Relation between the Water Content and Mechanical Properties of Hydrogels with Movable Cross-Links, Macromolecules, 57(16), 7745-7754 (2024).
    DOI:10.1021/acs.macromol.4c00732
  22. S. Zuo, Z. Wang, X. Jiang, Y. Zhao, P. Wen, J. Wang, J. Li, M. Tanaka, D. Shao, Y. Zhang, Z. Wang, Regulating tumor innervation by nanodrugs potentiates cancer immunochemotherapy and relieve chemotherapy-induced neuropathic pain, Biomaterials, 309, 122603 (2024).
    DOI: 10.1016/j.biomaterials.2024.122603
  23. M. Okada, S. C. Xie, Y. Kobayashi, H. Yanagimoto, D. Tsugawa, M. Tanaka, T. Nakano, T. Fukumoto, T. Matsumoto, Water-mediated on-demand detachable solid-state adhesive of porous hydroxyapatite for internal organ retractions, Adv. Healthcare Mater., 13(19), 2304616 (2024).
    DOI: 10.1002/adhm.202304616
  24. Y. Higuchi, M. A. Saleh, T. Anada, M. Tanaka, M. Hishida, Rotational Dynamics of Water near Osmolytes by Molecular Dynamics Simulations, J. Phys. Chem. B, 128(20), 5008–5017(2024).
    DOI : 10.1021/acs.jpcb.3c08470
  25. T. Kikuchi, T. Tominaga, D. Murakami, N. Souza, M. Tanaka, H. Seto, Detailed dynamical features of the slow hydration water in the vicinity of poly(ethylene oxide) chains, J. Chem. Phys., 160(6), 064902 (2024).
    DOI:10.1063/5.0185432
  26. K. Fukushima, S. Hakozaki, R. Lang, Y. Haga, S. Nakai, A. Narumi, M. Tanaka, T. Kato, Hydrolyzable and biocompatible aliphatic polycarbonates with ether functionalized side chains attached via amide linker, Polym. J. 56, 431–442 (2024).
    DOI:10.1038/s41428-023-00874-6
  27. K. Fujiura, M. Naito, Y. Tanaka, M. Tanaka, Y. Nakanishi, H. Ejima, L. Negishi, T. Kujirai, H. Kurumizaka, S. Ohta, K. Miyata, Development of stealth nanoparticles coated with poly(2-methoxyethyl vinyl ether) as an alternative to poly(ethylene glycol) , J. Appl. Polym. Sci. 141(11) e55044 (2024).
    DOI:10.1002/app.55044
  28. T. Miyano, Y. Ayukawa, T. Anada, I. Takahashi, H. Furuhashi, S. Tokunaga, A. Hirata, N. Nakashima, K. Kato, H Fukuda, Association between reduced posterior occlusal contact and Alzheimer’s disease onset in older Japanese adults: results from the LIFE Study, J. Alzheimers Dis., 97(2), 871-881 (2024).
    DOI : 10.3233/JAD-230449
  29. N. Hayakawa, M. Nishiura, T. Anada, S. Kobayashi, T. Sawada, T. Serizawa, M. Tanaka, Suspension Culture System for Isolating Cancer Spheroids using Enzymatically Synthesized Cellulose Oligomers, ACS Appl. Bio Mater., 7(1) 306-314 (2024).
    DOI:10.1021/acsabm.3c00901
  30. R. Wulandari, Y. Kusumastuti, A. Prasetya, Y. A. Purwestri, H. T. B. M. Petrus, A. Idrus, M. Tanaka,
    Antibacterial activity of copper nanoparticles (CuNPs) by the chemical reduction method,
    AIP Conf. Proc. 3073, 040001 (2024).
    DOI: 10.1063/5.0193978

    2023
  31. D. Miyake, J. He, F. Asai, M. Hara, T. Seki, S. Nishimura, M. Tanaka, Y. Takeoka, Optically Transparent and Color-Stable Elastomer with Structural Coloration under Elongation, Langmuir, 39(49) 17844-17852 (2023).
    DOI:10.1021/acs.langmuir.3c02442
  32. D. Murakami, M. Tanaka, Analyses on biocompatible polymer poly(2-methoxyethyl acrylate) (PMEA)/water interface, Acc. Mater. Surf. Res., 8(3), 159-165 (2023).
    wp-content_uploads_papers_vol8_no3_tanaka_tanaka_1006-1.pdf
  33. T. Ota, V. Montagna, Y. Higuchi, T. Kato, M. Tanaka, H. Sardon, K. Fukushima, Organocatalyzed ring-opening reactions of γ-carbonyl-substituted ε-caprolactones, RSC Adv., 13(40), 27764-27771 (2023).
    DOI:10.1039/d3ra01025b
  34. S. Nishimura, M. Tanaka, The Intermediate Water Concept for Pioneering Polymeric Biomaterials: A Review and Update, Bull. Chem. Soc. Jpn., 96(9), 1052-1070 (2023) .
    Account/Review for Memorial Collection for CSJ/OUP Co-Operative Publication
    Account/Review for Controlled Chemical Construction (C3) for Advanced Functions
    DOI : 10.1246/bcsj.20230168
  35. R. Koguchi,  K. Jankova, Y. Tanaka, A. Yamamoto, D. Murakami, Q. Yang, B. Ameduri, M. Tanaka, Altering the Bio-inert Properties of Surfaces by Fluorinated Copolymers of mPEGMA,  Biomater. Adv., 153, 213573 (2023).
    DOI: 10.1016/j.bioadv.2023.213573
  36. Y. Higaki, H. Toyama, T. Masuda, S. Kobayashi, M. Tanaka, Microphase Separation of Double-Hydrophilic Poly(carboxybetaine acrylate)-Poly(2-methoxyethyl acrylate) Block Copolymers in Water, Polym. J., 55, 1357-1365 (2023).
    DOI: 10.1038/s41428-023-00831-3 
  37. S. Kobayashi, M. Tanaka, Design of biomaterials through direct ring-opening metathesis polymerisation of functionalised cyclic alkenes, Mol. Syst. Des. Eng., 8, 960-991 (2023).
    DOI: 10.1039/d3me00063j
  38. A. Kumar, A. Sood, G. Agrawal, S. Thakur, V. K. Thakur, M. Tanaka, Y. K. Mishra, G. Christie, E. Mostafavi,R. Boukherroub, D. W. Hutmacher, S. S. Han, Polysaccharides, proteins, and synthetic polymers based multimodal hydrogels for various biomedical applications: A review, Int. J. Biol. Macromol., 247, 125606 (2023).
    DOI: 10.1016/j.ijbiomac.2023.125606
  39. P. Wen, W. Ke, A. Dirisala, K. Toh, M. Tanaka, J. Li, Stealth and pseudo-stealth nanocarriers, Adv. Drug Delivery Rev., 198, 114895 (2023).
    DOI: 10.1016/j.addr.2023.114895
  40. H. Kurita, S. Kobayashi, T. Anada, M. Tanaka, M. Todo, Cellular characterization of hiPS-CMs cultured on PMEA analogous polymers with different bound water content, Engineering Sciences Reports, Kyushu University, 45(1), 1-6 (2023).
    https://www.tj.kyushu-u.ac.jp/g_public/img/report_img/45-1.pdf
  41. R. Saeki, S. Kobayashi, R. Shimazui, T. Nii, A. Kishimura, M. Tanaka, T. Mori, Y. Katayama, Characterization of polypropyleneimine as an alternative transfection reagent, Anal. Sci.,  39, 1015-1020 (2023).
    DoI: 10.1007/s44211-023-00284-x
  42. M. Nomura, Y.  Yokoyama, D. Yoshimura, Y. Minagawa, A. Yamamoto, Y. Tanaka, N. Sekiguchi, D. Marukawa, M. Ichihara, H. Itakura, K. Matsumoto, Y. Morimoto, H. Tomihara, A. Inoue, T.  Ogino, N.  Miyoshi, H. Takahashi, H. Takahashi, M. Uemura, S. Kobayashi, T. Mizushima, T.  Anada, M. Mori, Y. Doki, M. Tanaka, H. Eguchi, H. Yamamoto, Simple Detection and Culture of Circulating Tumor Cells from Colorectal Cancer Patients Using Poly(2-Methoxyethyl Acrylate)-Coated Plates, Int. J. Mol. Sci., 24(4), 3949 (2023).
    DOI:10.3390/ijms24043949
  43. T. Ohta, M. Tanaka, S. Taki, H. Nakagawa, S. Nagase, Honeycomb-like Structured Film, a Novel Therapeutic Device, Suppresses Tumor Growth in an In Vivo Ovarian Cancer Model, Cancers, 15(1), 237 (2023).
    DOI:10.3390/cancers15010237
  44. M. Mabrouk, H. H. Beherei, S. Shiomoto, Y. Tanaka, L. Osama, M. Tanaka, Effect of titanium-doped bioactive glass on poly(2-hydroxyethyl methacrylate) hydrogel composites: bioactivity, intermediate water, cell proliferation, and adhesion force, Ceram. Int., 49(9), 13469-13481 (2023).
    DOI:10.1016/j.ceramint.2022.12.221
  45. C. Kojima, Y. Suzuki, Y. Ikemoto, M. Tanaka, A. Matsumoto, Comparative study of PEG and PEGylated dendrimers in their eutectic mixtures with water analyzed using X-ray diffraction and infrared spectroscopy, Polym. J.,  55, 63–73 (2023).
    DOI:10.1038/s41428-022-00700-5
  46. T. Miyano, T. Anada, M. Furuta, Y. Yamashita,Prefectural Differences in Chewing Ability in Questionnaire for Specific Health Checkup and Exploring of Related Factors, Journal of Dental Health, 73(2), 103-111 (2023).
    DOI: 10.5834/jdh.73.2_103

    2022
  47. T. Serizawa, S. Yamaguchi, M. Amitani, S. Ishii, H. Tsuyuki, Y. Tanaka, T. Sawada, I. Kawamura, G. Watanabe, M. Tanaka, Alkyl chain length-dependent protein nonadsorption and adsorption properties of crystalline alkyl β-celluloside assemblies, Colloids Surf., B, 220, 112898 (2022).
    DOI:10.1016/j.colsurfb.2022.112898
  48. S. Kobayashi, A. Sugasaki, Y. Yamamoto, Y. Shigenoi, A. Udaka, A. Yamamoto, M. Tanaka, Enrichment of Cancer Cells Based on Antibody-Free Selective Cell Adhesion, ACS Biomater. Sci. Eng., 8(10), 4547-4556 (2022).
    DOI:10.1021/acsbiomaterials.2c00662
  49. J. Park, T. Ueda, Y. Kawai, K. Araki, M. Kido, B. Kure, N. Takenaka, Y. Takashima, M. Tanaka, Simultaneous control of the mechanical properties and adhesion of human umbilical vein endothelial cells to suppress platelet adhesion on a supramolecular substrate, RSC Advances, 12(43), 27912-27917 (2022).
    DOI:10.1039/d2ra04885j
  50. M. A. Haque, D. Murakami, M. Tanaka, Cell Adhesion Strength Indicates the Antithrombogenicity of Poly(2-methoxyethyl acrylate) (PMEA): Potential Candidate for Artificial Small-Diameter Blood Vessel, Surfaces, 5(3), 365-382 (2022).
    DOI:10.3390/surfaces5030027
  51. Y. Watanabe, S. Takaoka, Y. Haga, K. Kishi, S. Hakozaki, A. Narumi, T. Kato, M. Tanaka, K. Fukushima, Organic carboxylate salt-enabled alternative synthetic routes for bio-functional cyclic carbonates and aliphatic polycarbonates, Polym. Chem., 13(36), 5193-5199 (2022).
    DOI:10.1039/d2py00705c
  52. M. A. Haque, D. Murakami, T. Anada, M. Tanaka, Poly(2-Methoxyethyl Acrylate) (PMEA)-Coated Anti-Platelet Adhesive Surfaces to Mimic Native Blood Vessels through HUVECs Attachment, Migration, and Monolayer Formation, Coatings, 12(6), 869 (2022).
    DOI:10.3390/coatings12060869
  53. S. Shiomoto, K. Inoue, H. Higuchi, S. Nishimura, H. Takaba, M. Tanaka, M. Kobayashi, Characterization of Hydration Water Bound to Choline Phosphate-Containing Polymers, Biomacromolecules, 23(7), 2999–3008 (2022).
    DOI:10.1021/acs.biomac.2c00484
  54. M. Mabrouk, H. H. Beherei, Y. Tanaka, M. Tanaka, Sol-gel silicate glass doped with silver for bone regeneration: Antibacterial activity, intermediate water, and cell death mode, Biomater. Adv., 138, 212965 (2022).
    DOI:10.1016/j.bioadv.2022.212965
  55. J.-J Huang, C.-H. Lin, Y. Tanaka, A. Yamamoto, S.-C Luo, M. Tanaka, Manipulation of Surface Hydration States by Tuning the Oligo(Ethylene Glycol) Moieties on PEDOT to Achieve Platelet-Resistant Bioelectrode Applications, Adv. Mater. Interfaces, 2200707 (2022).
    DOI:10.1002/admi.202200707
  56. Y. Ikemoto, Y. Harada, M. Tanaka, S. Nishimura, D. Murakami, N. Kurahashi, T. Moriwaki, K. Yamazoe, H. Washizu, Y. Ishii, H. Torii, Infrared Spectra and Hydrogen-Bond Configurations of Water Molecules at the Interface of Water-Insoluble Polymers under Humidified Conditions, The Journal of Physical Chemistry B, 126(22), 4143-4151 (2022).
    DOI:10.1021/acs.jpcb.2c01702
  57. S. Nishimura, K. Nishida, S. Shiomoto, M. Tanaka, Surfactant-free suspension polymerization of hydrophilic monomers with an oil-in-water system for the preparation of microparticles toward the selective isolation of tumor cells, Mater. Adv., 3(12), 5043-5054 (2022).
    DOI:10.1039/D2MA00129B
  58. K. Nishida, T. Anada, M. Tanaka, Roles of interfacial water states on advanced biomedical material design, Adv. Drug Delivery Rev., 186, 114310 (2022).
    DOI:10.1016/j.addr.2022.114310
  59. K. Nishida, K. Baba, D. Murakami, M. Tanaka, Nanoscopic analyses of cell-adhesive protein adsorption on poly(2-methoxyethyl acrylate) surfaces, Biomater. Sci., 10(11), 2953-2963 (2022).
    DOI:10.1039/D2BM00093H
  60. S. Nishimura, K. Nishida, T. Ueda, S. Shiomoto, M. Tanaka, Biocompatible poly(N-(ω-acryloyloxy-n-alkyl)-2-pyrrolidone)s with widely-tunable lower critical solution temperatures (LCSTs): a promising alternative to poly(N-isopropylacrylamide), Polym. Chem., 13(17), 2519–2530 (2022).
    DOI:10.1039/d2py00154c
  61. M. Hishida, R. Anjum, T. Anada, D. Murakami, M. Tanaka, Effect of Osmolytes on Water Mobility Correlates with Their Stabilizing Effect on Proteins, J. Phys. Chem. B, 126(13), 2466–2475(2022).
    DOI:10.1021/acs.jpcb.1c10634
  62. T. Tominaga, M. Hishida, D. Murakami, Y. Fujii, M. Tanaka, H. Seto, Experimental Evidence of Slow Mode Water in the Vicinity of Poly(ethylene oxide) at Physiological Temperature, J. Phys. Chem. B, 126(8), 1758–1767 (2022).
    DOI:10.1021/acs.jpcb.1c09044
  63. K. Nishida, S. Nishimura, M. Tanaka, Selective Accumulation to Tumor Cells with Coacervate Droplets Formed from a Water-Insoluble Acrylate Polymer, Biomacromolecules, 23(4), 1569–1580 (2022).
    DOI:10.1021/acs.biomac.1c01343
  64. K. Nishida, S. Sekida, T. Anada, M. Tanaka, Modulation of Biological Responses of Tumor Cells Adhered to Poly(2-methoxyethyl acrylate) with Increasing Cell Viability under Serum-Free Conditions, ACS Biomater. Sci. Eng., 8(2), 672–681 (2022).
    DOI:10.1021/acsbiomaterials.1c01469
  65. D. Murakami, K. Yamazoe, S. Nishimura, N. Kurahashi, T. Ueda, J. Miyawaki, Y. Ikemoto, M. Tanaka, Y. Harada, Hydration Mechanism in Blood-Compatible Polymers Undergoing Phase Separation, Langmuir, 38(3), 1090-1098 (2022).
    DOI:10.1021/acs.langmuir.1c02672
  66. D. Murakami, S. Nishimura, Y. Tanaka, M. Tanaka, Observing the Repulsion Layers on Blood-compatible Polymer-grafted Interfaces by Frequency Modulation Atomic Force Microscopy, Biomater. Adv., 133, 112596 (2022).
    DOI:10.1016/j.msec.2021.112596
  67. K. Fukushima, K. Matsuzaki, M. Oji, Y. Higuchi, G. Watanabe, Y. Suzuki, M. Kikuchi, N. Fujimura,  N. Shimokawa, H. Ito, T. Kato, S. Kawaguchi, M. Tanaka, Anisotropic, Degradable Polymer Assemblies Driven by a Rigid Hydrogen-Bonding Motif That Induce Shape-Specific Cell Responses, Macromolecules, 55(1), 15–25 (2022).
    DOI:10.1021/acs.macromol.1c01894
  68. S. Nishimura, K. Nishida, M. Tanaka, A β-hairpin peptide with pH-controlled affinity for tumor cells, Chem. Commun., 58(4), 505-508 (2022).
    DOI:10.1039/D1CC06218B
  69. R. Koguchi, K. Jankova, M. Tanaka, Fluorine-containing bio-inert polymers: Roles of intermediate water, Acta Biomater., 138(15), 34-56 (2022).
    DOI:10.1016/j.actbio.2021.10.027
  70. C. Ueda, J. Park, K. Hirose, S. Konishi, Y. Ikemoto, M. Osaki, H. Yamaguchi, A. Harada, M. Tanaka, G. Watanabe, Y. Takashima, Behavior of supramolecular cross-links formed by host-guest interactions in hydrogels responding to water contents, Supramol. Mater., 1, 100001 (2022).
    DOI:10.1016/j.supmat.2021.100001

    2021
  71. Y. Asawa, K. Nishida, K. Kawai, K. Domae, H. S. Ban, A. Kitazaki, H. Asami, J. Kohno, S. Okada, H. Tokuma, D. Sakano, S. Kume, M. Tanaka, H. Nakamura, Carborane as an Alternative Efficient Hydrophobic Tag for Protein Degradation, Bioconjugate Chem., 32(11), 2377–2385 (2021).
    DOI:10.1021/acs.bioconjchem.1c00431
  72. W. Lee, S.-H. Jeong, Y.-W. Lim, H. Lee, J. Kang, H. Lee, l. Lee, H-S. Han, S. Kobayashi, M. Tanaka, B.-S. Bae, Conformable microneedle pH sensors via the integration of two different siloxane polymers for mapping peripheral artery disease, Sci. Adv., 7(48), eabi6290 (2021).
    DOI:10.1126/sciadv.abi6290
  73. T. Ishizawa, N. Makino, Y. Kakizaki, A. Matsuda, Y. Toyokawa, S. Ooyama, M. Tanaka, Y. Ueno, Biosafety of a novel covered self-expandable metal stent coated with poly(2-methoxyethyl acrylate) in vivo, PLoS ONE, 16(9), e0257828 (2021).
    DOI:10.1371/journal.pone.0257828
  74. R. Chang, E. Angelo Q. Mondarte, D. Palai, T. Sekine, A. Kashiwazaki, D. Murakami, M. Tanaka, T. Hayashi, Protein- and Cell-Resistance of Zwitterionic Peptide-Based Self-Assembled Monolayers: Anti-Biofouling Tests and Surface Force Analysis, Front. Chem., 9, 748017 (2021). Part of the Research Topic: Interfacial Water: A Physical Chemistry Perspective, Volume II
    DOI:10.3389/fchem.2021.748017
  75. Y. Fujii, T. Tominaga, D. Murakami, M. Tanaka, H. Seto, Local Dynamics of the Hydration Water and Poly(Methyl Methacrylate) Chains in PMMA Networks, Front. Chem., 9, 728738 (2021). Part of the Research Topic: Interfacial Water: A Physical Chemistry Perspective, Volume II
    DOI:10.3389/fchem.2021.728738
  76. M. Osaki, S. Yonei, C. Ueda, R. Ikura, J. Park, H. Yamaguchi, A. Harada, M. Tanaka, Y. Takashima, Mechanical Properties with Respect to Water Content of Host-Guest Hydrogels, Macromolecules, 54(17), 8067–8076(2021).
    DOI:10.1021/acs.macromol.1c00970
  77. T. Ueda, D. Murakami, M. Tanaka, Effect of amount of hydrated water and mobility of hydrated poly(2-methoxyethyl acrylate) on denaturation of adsorbed fibrinogen, J. Polym Sci., 59(22), 2763-2770 (2021).
    DOI:10.1002/pol.20210496
  78. K. Nishida, T. Anada, S. Kobayashi, T. Ueda, M. Tanaka, Effect of bound water content on cell adhesion strength to water-insoluble polymers, Acta Biomater., 134(15), 313-324(2021).
    DOI:10.1016/j.actbio.2021.07.058
  79. M. Mabrouk, H.H. Beherei, Y. Tanaka, M. Tanaka, Investigating the Intermediate Water Feature of Hydrated Titanium Containing Bioactive Glass, Int. J. Mol. Sci., 22(15), 8038, (2021).
    DOI:10.3390/ijms22158038
  80. S. Liu, S. Kobayashi, S. Nishimura, T. Ueda, M. Tanaka, Effect of pendant groups on the blood compatibility and hydration states of poly(2-oxazoline)s, J. Polym Sci., 59(21), 2559-2570 (2021).
    DOI:10.1002/pol.20210410
  81. R. Anjum, S. Nishimura, S. Kobayashi, K. Nishida, T. Anada, M. Tanaka, Protein Stabilization Effect of Zwitterionic Osmolyte-bearing Polymer, Chem. Lett., 50(9), 1699-1702(2021).
    DOI:10.1246/cl.210335
  82. M. Yamazaki, Y. Sugimoto, D. Murakami, M. Tanaka, T. Ooya, Effect of Branching Degree of Dendritic Polyglycerols on Plasma Protein Adsorption: Relationship between Hydration States and Surface Morphology, Langmuir, 37(28), 8534–8543 (2021).
    DOI:10.1021/acs.langmuir.1c01003
  83. T. Kanamaru, M. Araki, R. Takahashi, S. Fujii, T. Shikata, D. Murakami, M. Tanaka, K. Sakurai, First Observation of the Hydration Layer around Polymer Chain by Scattering and Its Relationship to Thromboresistance: Dilute Solution Properties of PMEA in THF/Water, J. Phys. Chem. B, 125(26), 7251–7261 (2021).
    DOI:10.1021/acs.jpcb.1c01864
  84. C. Yoshikawa, S. Hattori, C-F. Huang, H. Kobayashi, M. Tanaka, In vitro and in vivo blood compatibility of concentrated polymer brushes, J. Mater. Chem. B, 9, 5794-5804 (2021).
    DOI:10.1039/D1TB00886B
  85. S. Liu, S. Kobayashi, T. Sonoda, M. Tanaka, Poly(tertiary amide acrylate) Copolymers Inspired by Poly(2-oxazoline)s: Their Blood Compatibility and Hydration States, Biomacromolecules, 22(6), 2718-2728 (2021).
    DOI:10.1021/acs.biomac.1c0041
  86. A. T. Kuo, S. Urata, R. Koguchi, T. Sonoda, S. Kobayashi, M. Tanaka, Effects of Side-Chain Spacing and Length on Hydration States of Poly(2-methoxyethyl acrylate) Analogues: A Molecular Dynamics Study, ACS Biomater. Sci. Eng., 7(6), 2383-2391 (2021).
    DOI:10.1021/acsbiomaterials.1c00388
  87. A. Tsujimoto, H. Uehara, H. Yoshida, M. Nishio, K. Furuta, T. Inui, A. Matsumoto, S. Morita, M. Tanaka, C. Kojima, Different hydration states and passive tumor targeting ability of polyethylene glycol-modified dendrimers with high and low PEG density, Mater. Sci. Eng., C, 126, 112159 (2021).
    DOI:10.1016/j.msec.2021.112159
  88. R. Anjum, K. Nishida, H. Matsumoto, D. Murakami, S. Kobayashi, T. Anada, M. Tanaka, Attachment and Growth of Fibroblast Cells on Poly (2-Methoxyethyl Acrylate) Analog Polymers as Coating Materials, Coatings, 11(4), 461(2021).
    DOI:10.3390/coatings11040461
  89. S. Nishimura, T. Ueda, D. Murakami, M. Tanaka, Chain-End Effect for Intermediate Water Formation of Poly(2-Methoxyethyl Acrylate), Organic Materials, 03(02), 214-220(2021).
    DOI:10.1055/a-1441-8239
  90. T. Sonoda, S. Kobayashi, M. Tanaka, Periodically Functionalized Linear Polyethylene with Tertiary Amino Groups via Regioselective Ring-Opening Metathesis Polymerization, Macromolecules, 54(6), 2862–2872 (2021).
    DOI:10.1021/acs.macromol.0c02611
  91. V. Montagna, J. Takahashi, M-Y. Tsai, T. Ota, N. Zivic, S. Kawaguchi, T. Kato, M. Tanaka, H. Sardón, K. Fukushima, Methoxy-Functionalized Glycerol-Based Aliphatic Polycarbonate: Organocatalytic Synthesis, Blood Compatibility, and Hydrolytic Property, ACS Biomater. Sci. Eng., 7(2), 472–481 (2021).
    DOI:10.1021/acsbiomaterials.0c01460
  92. Y. Toyokawa, S. Kobayashi, H. Tsuchiya, T. Shibuya, M. Aoki, J. Sumiya, S. Ooyama, T. Ishizawa, N. Makino, Y. Ueno, M. Tanaka, A fully covered self-expandable metallic stent coated with poly (2-methoxyethyl acrylate) and its derivative: In vitro evaluation of early-stage biliary sludge formation inhibition, Mater. Sci. Eng., C, 120, 111386 (2021).
    DOI: 1016/j.msec.2020.111386
  93. T. Ueda, D. Murakami, M. Tanaka, Effect of interfacial structure based on grafting density of poly(2-methoxyethyl acrylate) on blood compatibility, Colloids Surf., B, 199, 111517 (2021) .
    DOI:10.1016/j.colsurfb.2020.111517
  94. M. Tanaka, S. Morita, T. Hayashi, Role of interfacial water in determining the interactions of proteins and cells with hydrated materials, Colloids Surf., B, 198, 111449 (2021).
    DOI:10.1016/j.colsurfb.2020.111449

    2020
  95. K. Athanasopulu, D. Caltzidou, A. Sekishita, L. Kutuzova, G. Lorenz, M. Tanaka, R.  Kemkemer,  Sulfated Hyaluronan coating of polyurethanebased implant materials, Current Directions in Biomedical Engineering, 6(3), 20203115 (2020).
    DOI:10.1515/cdbme-2020-3115
  96. A.T. Kuo, S. Urata, R. Koguchi, T. Sonoda, S. Kobayashi, M. Tanaka, Molecular Dynamics Study on the Water Mobility and Side-chain Flexibility of Hydrated Poly(ω-methoxyalkyl acrylate)s, ACS Biomater. Sci. Eng., 6(12), 6690-6700 (2020).
    DOI:10.1021/acsbiomaterials.0c01220
  97. T. Sonoda, S. Kobayashi, K. Herai, M. Tanaka, Side-Chain Spacing Control of Derivatives of Poly(2-methoxyethyl acrylate): Impact on Hydration States and Antithrombogenicity, Macromolecules, 53(19), 8570-8580 (2020).
    DOI: 10.1021/acs.macromol.0c01144
  98. S. Nishimura, T. Ueda, S. Kobayashi, M. Tanaka, Silsesquioxane/Poly(2-methoxyethyl acrylate) Hybrid with Both Antithrombotic and Endothelial Cell Adhesive Properties, ACS Appl. Polym. Mater., 2(11), 4790-4801 (2020) (Front Cover in this issue).
    DOI: 10.1021/acsapm.0c00776
  99. A.T. Kuo, T. Sonoda, S. Urata, R. Koguchi, S. Kobayashi, M. Tanaka, Elucidating the Feature of Intermediate Water in Hydrated Poly(ω-methoxyalkyl acrylate)s by Molecular Dynamics Simulation and Differential Scanning Calorimetry Measurement, ACS Biomater. Sci. Eng., 6(7), 3915-3924 (2020).
    DOI: 10.1021/acsbiomaterials.0c00746
  100. R. Koguchi, K. Jankova, Y. Hayasaka, D. Kobayashi, Y. Amino, T. Miyajima, S. Kobayashi, D. Murakami, K. Yamamoto, M. Tanaka, Understanding the Effect of Hydration on the Bio-inert Properties of 2-Hydroxyethyl Methacrylate Copolymers with Small Amounts of Amino- or/and Fluorine-Containing Monomers, ACS Biomater. Sci. Eng., 6(5), 2855-2866 (2020).
    DOI: 10.1021/acsbiomaterials.0c00230
  101. M-Y. Tsai, F. Aratsu, S. Sekida, S. Kobayashi, M. Tanaka, Blood-Compatible Poly(2-methoxyethyl acrylate) Induces Blebbing-like Phenomenon and Promotes Viability of Tumor Cells in Serum-Free Medium, ACS Appl. Bio Mater., 3(4), 1858-1864 (2020).
    DOI: 10.1021/acsabm.9b00885
  102. D. Murakami, Y. Segami, T. Ueda, M. Tanaka, Control of interfacial structures and anti-platelet adhesion property of blood-compatible random copolymers, J. Biomater. Sci. Polym. Ed., 31(2), 207-218 (2020).
    DOI: 10.1080/09205063.2019.1680930
  103. M. Watanabe, Y. Tanaka, D. Murakami, M. Tanaka, M. Kawai, T. Mitsumata, Optimal Plasticizer Content for Magnetic Elastomers Used for Cell Culture Substrate, Chem. Lett., 49(3), 280-283 (2020).
    DOI: 10.1246/cl.190929

    2019
  104. R. Sakamoto, K. Nakamoto, A. Kitajo, D. Murakami, H. Hirai, M. Tanaka, Y.Zhou, T. Yamaguchi, S. Okada, Highly Concentrated Aqueous Electrolytes for Building High Voltage Aqueous Batteries, The Electrochemical Society of Japan, 87(Autumn), 220-226 (2019).
    DOI: 10.5796/denkikagaku.19-FE0022
  105. M. Tanaka, S. Kobayashi, D. Murakami, F. Aratsu, A. Kashiwazaki, T. Hoshiba, K. Fukushima, Design of Polymeric Biomaterials: The “Intermediate Water Concept”, Bull. Chem. Soc. Jpn., 92, 2043-2057 (2019).
    DOI: 10.1246/bcsj.20190274
  106. K. Jankova, I. Javakhishvili, S. Kobayashi, R. Koguchi, D. Murakami, T. Sonoda, M. Tanaka, Hydration States and Blood Compatibility of Hydrogen-Bonded Supramolecular Poly(2-methoxyethyl acrylate), ACS Appl. Bio Mater., 2(10), 4154-4161 (2019).
    DOI: 10.1021/acsabm.9b00363
  107. T. Araki, F. Yoshida, T. Uemura, Y. Noda, S. Yoshimoto, T. Kaiju, T. Suzuki, H. Hamanaka, K. Baba, H. Hayakawa, T. Yabumoto, H. Mochizuki, S. Kobayashi, M. Tanaka, M. Hirata, T. Sekitani, Long-Term Implantable, Flexible, and Transparent Neural Interface Based on Ag/Au Core–Shell Nanowires, Adv. Healthcare Mater., 8(10), 1900130 (2019).
    DOI: 10.1002/adhm.201900130
  108. R. Koguchi, K. Jankova, N. Tanabe, Y. Amino, Y. Hayasaka, D. Kabayashi, T. Miyajima, K. Yamamoto, M. Tanaka, Controlling the Hydration Structure with a Small Amount of Fluorine To Produce Blood Compatible Fluorinated Poly(2-methoxyethyl acrylate), Biomacromolecules, 20(6), 2265-2275 (2019).
    DOI: 10.1021/acs.biomac.9b00201
  109. A.-T. Kuo, S. Urata, R. Koguchi, K. Yamamoto, M. Tanaka, Analyses of equilibrium water content and blood compatibility for Poly(2-methoxyethyl acrylate) by molecular dynamics simulation, Polymer, 170(29), 76-84 (2019).
    DOI: 10.1016/j.polymer.2019.03.001
  110. M. Okada, E. Hara, D. Kobayashi, S. Kai, K. Ogura, M. Tanaka, T. Matsumoto, Intermediate Water on Calcium Phosphate Minerals: Its Origin and Role in Crystal Growth, ACS Applied Bio Materials, 2(3), 981-986 (2019).
    DOI: 10.1021/acsabm.9b00014
  111. D. Murakami, N. Mawatari, T. Sonoda, A. Kashiwazaki, M. Tanaka, Effect of Molecular Weight of Poly(2-methoxyethyl acrylate) on Interfacial Structure and Blood Compatibility. Langmuir, 35(7), 2808-2813 (2019).
    DOI: 10.1021/acs.langmuir.8b02971

    2018
  112. W. Lee, S. Kobayashi, M. Nagase, Y. Jimbo, I. Saito, Y. Inoue, T. Yambe, M. Sekino, G. G Malliaras, T. Yokota, M. Tanaka, T. Someya, Nonthrombogenic, stretchable, active multielectrode array for electroanatomical mapping, Sci. Adv., 4(10), eaau2426 (2018).
    DOI: 10.1126/sciadv.aau2426
  113. T. Ueda, D. Murakami, M. Tanaka, Analysis of Interaction Between Interfacial Structure and Fibrinogen at Blood-Compatible Polymer/Water Interface, Front. Chem., 6, 542 (2018). Part of the Research Topic: Polymer Surface Chemistry: Biomolecular Engineering and Biointerfaces
    DOI: 10.3389/fchem.2018.00542
  114. F. Khan, F. Aratsu, S. Kobayashi, M. Tanaka, A simple strategy for robust preparation and characterisation of hydrogels derived from chitosan and amino functional monomers for biomedical applications, J. Mater. Chem. B, 6(31), 5115-5129 (2018).
    DOI: 10.1039/C8TB00865E
  115. D. Murakami, Y. Kitahara, S. Kobayashi, M. Tanaka, Thermosensitive Polymer Biocompatibility Based on Interfacial Structure at Biointerface, ACS Biomater. Sci. Eng., 4, 1591-1597 (2018). 
    DOI: 10.1021/acsbiomaterials.8b00081
  116. M. Mabrouk, H. H.  Beherei, S. ElShebiney, M. Tanaka, Newly developed controlled release subcutaneous formulation for tramadol hydrochloride, Saudi Pharmaceutical Journal, 26(4), 585-592 (2018).
    DOI: 10.1016/j.jsps.2018.01.014
  117. F. Khan, M. Tanaka, Designing Smart Biomaterials for Tissue Engineering, Int. J. Mol. Sci., 19(1), 17 (2018). 
    DOI: 10.3390/ijms19010017
  118. T. Hoshiba, K. Sato, N. Kawazoe, G. CHEN, M. Tanaka, Chondrocyte Shapes and Detachment on a Thermoresponsive Poly(2-methoxyethyl acrylate) Analog for the Development of New Chondrocytes Subculture Substrate, Chem. Lett., 47(1), 107-109 (2018).
    DOI: 10.1246/cl.170889

    2017
  119. S. Kobayashi, M. Wakui, Y. Iwata, M. Tanaka, Poly(ω-methoxyalkyl acrylate)s: Nonthrombogenic Polymer Family with Tunable Protein Adsorption, Biomacromolecules, 18 (12), 4214-4223 (2017).
    DOI: 10.1021/acs.biomac.7b01247
  120. K. Fukushima, Y. Inoue, Y. Haga, T. Ota, K. Honda, C. Sato, M. Tanaka, Monoether-Tagged Biodegradable Polycarbonate Preventing Platelet Adhesion and Demonstrating Vascular Cell Adhesion: A Promising Material for Resorbable Vascular Grafts and Stents, Biomacromolecules, 18 (11), 3834–3843 (2017).
    DOI: 10.1021/acs.biomac.7b01210
  121. T. Hoshiba, H. Maruyama, K. Sato, C. Endo, N. Kawazoe, G. Chen, M. Tanaka, Maintenance of Cartilaginous Gene Expression of Serially Subcultured Chondrocytes on Poly(2-Methoxyethyl Acrylate) Analogous Polymers, Macromol. Biosci.,17(12),1700297(2017) .
    DOI: 10.1002/mabi.201700297
  122. K. Fukushima, K. Honda, Y. inoue, M. Tanaka, Synthesis of antithrombotic poly(carbonate-urethane)s through a sequential process of ring-opening polymerization and polyaddition facilitated by organocatalysts, Eur. Polym. J., Vol. 95, 728-736 (2017).
    DOI: 10.1016/j.eurpolymj.2017.07.001
  123. K. Sato, S. Kobayashi, A. Sekishita, M. Wakui, M. Tanaka, Synthesis and Thrombogenicity Evaluation of Poly(3-methoxypropionic acid vinyl ester): A Candidate for Blood-Compatible Polymers, Biomacromolecules, 18(5), 1609-1616 (2017).
    DOI: 10.1021/acs.biomac.7b00221
  124. T. Hoshiba, A.Yoshihiro, M. Tanaka, Evaluation of initial cell adhesion on poly (2-methoxyethyl acrylate) (PMEA) analogous polymers, J. Biomat. Sci. Polym. Ed., 28, 986-999 (2017).
    DOI: 10.1080/09205063.2017.1312738
  125. T. Sekine, S. Asatyas, C. Sato, S. Morita, M. Tanaka, T. Hayashi, Surface force and vibrational spectroscopic analyses of interfacial water molecules in the vicinity of methoxy-tri(ethylene glycol)-terminated monolayers: mechanisms underlying the effect of lateral packing density on bioinertness, J. Biomat. Sci. Polym. Ed., 28, 1231-1243 (2017).
    DOI: 10.1080/09205063.2017.1303120
  126. Y. Inoue,  T. Yokota, T. Sekitani, A. Kaneko, T. Woo, S. Kobayashi, T.Shibuya, M. Tanaka, H. Koshukegawa, I. Saito, T. Isoyama, Y. Abe, T.Yambe, T. Someya, M. Sekino, Antithrombotic Protein Filter Composed of Hybrid Tissue-Fabric Material has a Long Lifetime, Ann. Biomed. Eng., 45(5), 1352-1364 (2017).
    DOI: 10.1007/s10439-016-1781-5
  127. T. Hirata, H. Matsuno, D. Kawaguchi, M. Inutsuka, T. Hirai, M. Tanaka, K. Tanaka, Dynamics of a bioinert polymer in hydrated states by dielectric relaxation spectroscopy, Phys. Chem. Chem. Phys., 19,1389-1394 (2017).
    DOI: 10.1039/c6cp07322k

    2016
  128. T. Hoshiba, E. Nemoto, K. Sato, H. Maruyama, C. Endo, M. Tanaka, Promotion of Adipogenesis of 3T3-L1 Cells on Protein AdsorptionSuppressing Poly(2-methoxyethyl acrylate) Analogs, Biomacromolecules, 17(11),3808-3815 (2016).
    DOI:10.1021/acs.biomac.6b01340
  129. D. Murakami, S. Kobayashi, M. Tanaka, Interfacial Structures and Fibrinogen Adsorption at Blood-Compatible Polymer/Water Interfaces, ACS Biomater. Sci. Eng., 2(12), 2122–2126 (2016).
    DOI:0.1021/acsbiomaterials.6b00415
  130. K. Osawa, S. Kobayashi, M. Tanaka, Synthesis of Sequence-Specific Polymers with Amide Side Chains via Regio-/Stereoselective Ring-Opening Metathesis Polymerization of 3‑Substituted cis-Cyclooctene, Macromolecules, 49(21), 8154-8161 (2016).
    DOI:10.1021/acs.macromol.6b01829
  131. T. Hoshiba, M. Tanaka, Integrin-independent Cell Adhesion Substrates: Possibility of Applications for Mechanobiology Research, Anal. Sci., 32(11),1151-1158 (2016).
    DOI:10.1021/acs.macromol.6b01829
  132. T. Hoshiba, T. Orui, C. Endo, K. Sato, A. Yoshihiro, Y. Minagawa, M.Tanaka, Adhesion-based simple capture and recovery of circulating tumor cells using a blood-compatible and thermo-responsive polymer-coated substrate, RSC Adv., 6, 89103-89112 (2016).
    DOI:10.1039/C6RA15229E
  133. A. Basterretxea, Y. Haga, A. Sanchez-Sanchez, M. Isik, L. Irusta, M. Tanaka, K. Fukushima, H. Sardon, Biocompatibility and hemocompatibility evaluation of polyether urethanes synthesized using DBU organocatalyst, Eur. Polym. J., 84, 750-758 (2016).
    DOI:10.1016/j.eurpolymj.2016.08.008
  134. T. Hoshiba, M.Tanaka, Decellularized matrices as in vitro models of extracellular matrix in tumor tissues at different malignant levels:Mechanism of 5-fluorouracil resistance in colorectal tumor cells, Biochim. Biophys. Acta, Mol. Cell. Res., 1863(11),2749-2757 (2016).
    DOI:10.1016/j.bbamcr.2016.08.009.
  135. K. Kono, H. Hiruma, S. Kobayashi, Y. Sato,  M.Tanaka, R. Sawada, S. Niimi, In Vitro Endothelialization Test of Biomaterials Using Immortalized Endothelial Cells, PLoS One, 11(6), e0158289 (2016).
    DOI:10.1371/journal.pone.0158289
  136. S. Kobayashi, K. Fukuda, M. Kataoka, M. Tanaka, Regioselective Ring-Opening Metathesis Polymerization of 3-Substituted Cyclooctenes with Ether Side Chains, Macromolecules, 49(7), 2493-2501 (2016).
    DOI:10.1021/acs.macromol.6b00273
  137. C. Sato, M. Aoki, M. Tanaka, Blood-compatible poly(2-methoxyethyl acrylate) for the adhesion and proliferation of endothelial and smooth muscle cells, Colloids Surf., B,145, 586-596 (2016).
    DOI:10.1016/j.colsurfb.2016.05.057
  138. T. Hoshiba, M. Nikaido, S.Yagi, I. Konno, A. Yoshihiro, M. Tanaka, Blood-compatible poly (2-methoxyethyl acrylate) for the adhesion and proliferation of lung cancer cells toward the isolation and analysis of circulating tumor cells, Journal of Bioactive and Compatible Polymers, 31(4), 361-372 (2016).
    DOI:10.1177/0883911515618976
  139. H. Choi, M. Tanaka, K. Sugimoto, Difference in Cell Proliferation and Spontaneous Mediator Release Between Two Mast Cell Lines, NCL-2 and RBL-2H3 on Honey Comb-like Structured Film, Journal of Nanotechnology: Nanomedicine & Nanobiotechnology, 3(009) (2016).
    DOI:10.24966/NTMB-2044/100009
  140.  T. Hoshiba, G. Chen, C. Endo, H. Maruyama, M. Wakui, E. Nemoto, N. Kawazoe, M. Tanaka. Decellularized Extracellular Matrix as an In Vitro Model to Study the Comprehensive Roles of the ECM in Stem Cell Differentiation. Stem Cells Int., 2016, 6397820 (2016).
    DOI:10.1155/2016/6397820

    2015
  141. T. Hoshiba, T. Otaki, E. Nemoto, H. Maruyama, M. Tanaka, Blood-Compatible Polymer for Hepatocyte Culture with High Hepatocyte-Specific Functions toward Bioartificial Liver Development. ACS Appl. Mater. Interfaces 7(32), 18096-18103 (2015).
    DOI:10.1021/acsami.5b05210
  142. T. Hirata, H. Matsuno, D. Kawaguchi, N. Yamada, M. Tanaka, K. Tanaka, Construction of a blood-compatible interface based on surface segregation in a polymer blend, Polymer, 78, 219-224 (2015).
    DOI:10.1016/j.polymer.2015.10.001
  143. F. Khan, M. Tanaka, S.R. Ahmad, Fabrication of polymeric biomaterials: a strategy for tissue engineering and medical devices, J. Mater. Chem. B, 3, 8224-8249 (2015).
    DOI:10.1039/C5TB01370D
  144. T. Hoshiba, E. Nemoto, K. Sato, T. Orui, T. Otaki, A. Yoshihiro, M. Tanaka. Regulation of the Contribution of Integrin to Cell Attachment on Poly(2-Methoxyethyl Acrylate) (PMEA) Analogous Polymers for Attachment-Based Cell Enrichment. PLoS One,10(8), e0136066 (2015).
    DOI:10.1371/journal.pone.0136066
  145. T. Sekine, Y. Tanaka, C. Sato, M. Tanaka, T. Hayashi, Evaluation of Factors To Determine Platelet Compatibility by Using Self-Assembled Monolayers with a Chemical Gradient, Langmuir, 31,7100-7105 (2015).
    DOI:10.1021/acs.langmuir.5b01216
  146. K. Sato, S. Kobayashi, M. Kusakari, S. Watahiki, M. Oikawa, T. Hoshiba,  M. Tanaka, The Relationship Between Water Structure and Blood Compatibility in Poly(2-methoxyethyl Acrylate) (PMEA) Analogues, Macromol. Biosci., 15, 1296-1303 (2015).
    DOI:10.1002/mabi.201500078
  147.  T. Hirata, H. Matsuno, D. Kawaguchi, N. Yamada, M. Tanaka, K. Tanaka, Effect of interfacial structure on bioinert property of poly(2-methoxyethyl acrylate)/ poly(methyl methacrylate) blend films in water, Phys. Chem. Chem. Phys., 17,17399-17405 (2015).
    DOI:10.1039/c5cp01972a
  148. K. Fukushima, M. Tsai, T. Ota, Y. Haga, K. Matsuzaki, Y. Inoue, M. Tanaka, Evaluation of the hemocompatibility of hydrated biodegradable aliphatic carbonyl polymers with a subtle difference in the backbone structure based on the intermediate water concept and surface hydration, Polym. J., 47, 469-473 (2015). 
    DOI:10.1038/pj.2015.22
  149. T. Hirata, H. Matsuno, D. Kawaguchi, T. Hirai, N. Yamada, M. Tanaka, K. Tanaka, Effect of Local Chain dynamics on a Bio-inert Interface, Langmuir, 31, 3661-3667 (2015).
    DOI:10.1021/acs.langmuir.5b00258
  150. M. Tanaka, K. Sato, E. Kitakami, S. Kobayashi, T. Hoshiba, K. Fukushima, Design of biocompatible and biodegradable polymers based on intermediate water concept, Polymer Journal, 47, 114-121 (2015). Invited paper: Special Issue on Fusion Materials, Most Accessed Papers(September – December 2015)
    DOI:10.1038/pj.2014.129
  151. T. Hoshiba, M. Tanaka, Optimization of the tissue source, malignancy, and initial substrate of tumor cell-derived matrices to increase cancer cell chemoresistance against 5-fluorouracil. Biochem. Biophys.Res. Commun., 457, 353-357 (2015).
    DOI:10.1016/j.bbrc.2014.12.116

    2014
  152. S. Morita, M. Tanaka, Effect of Sodium Chloride on Hydration Structures of PMEA and P(MPC-r-BMA), Langmuir, 30,10698-10703 (2014).
    DOI:10.1021/la502550d
  153. K. Sugimoto, H. Choi, M. Tanaka, Honeycomb-like structured film regulates mediator release from non-tumor mast cells,  European Journal of Inflammation, 12, 515-520 (2014).
    DOI:10.1177/1721727X1401200313
  154. E. Kitakami, M. Aoki, C. Sato, H. Ishihata, M. Tanaka, Adhesion and proliferation of human periodontal ligament cells on poly(2-methoxyethyl acrylate), BioMed Resarch International, 2014, 102648 (2014).
    DOI:10.1155/2014/102648
  155. T. Hoshiba, M. Nikaido, M. Tanaka, Characterization of the Attachment Mechanisms of Tissue-Derived Cell Lines to Blood-Compatible Polymers, Adv. Healthcare Mater., 3, 775-784 (2014).
    DOI:10.1002/adhm.201300309
  156. H. Choi, M. Tanaka, T. Hiragun, M. Hide, K. Sugimoto, Non-tumor mast cells cultured in vitro on a honeycomb-like structured film prpliferate with multinucleateaed formation, Nanomedicine, 10, 313-319 (2014).
    DOI:10.1016/j.nano.2013.08.011
  157. J.O. Eniwumide, M.Tanaka, N. Nagai, Y. Morita, J.De Bruijn , S. Yamamoto, S. Onodera, E. Kondo, K. Yasuda, M. Shimomura. The Morphology and Functions of Articular Chondrocytes on a Honeycomb-Patterned Surface, BioMed Research International, 2014, 710354 (2014).
    DOI:10.1155/2014/710354

    2013
  158. M. Birch, M. Tanaka, G. Kirmizidis, S. Yamamoto, M. Shimomura, Microporous “Honeycomb” Films Support Enhanced Bone Formation in VitroTissue Engineering A, 19, 2087-2096, 2013.
    DOI:10.1089/ten.TEA.2012.0729
  159. T. Hoshiba, M. Tanaka, Breast cancer cell behaviors on staged tumorigenesis-mimicking matrices derived from tumor cells at various malignant stages, Biochemical and Biophysical Research Communications, 439, 291-296, 2013.
    DOI:10.1016/j.bbrc.2013.08.038
  160. M. Tanaka, T. Hayashi, S. Morita, The roles of water molecule at the biointerface of medical polymers, Polym. J., 45, 701-710, 2013. (Invited paper: SPSJ Asahi Kasei Award).
    DOI:10.1038/pj.2012.229

    2012
  161. T. Hayashi, Y. Tanaka, Y. Koide, M. Tanaka, M. Hara, Mechanism Underlying Bioinertness of Self-assembled Monolayers of Oligo(ethyleneglycol)-terminated Alkanethiols on Gold: Protein Adsorption, Platelet Adhesion, and Surface Forces, Physical Chemistry Chemical Physics, 14,10196-10206, 2012.
    DOI:10.1039/c2cp41236e     
  162. I. Javakhishvili, M. Tanaka, K. Ogura, K. Jankova, S. Hvilsted, Synthesis of graft copolymers based on poly(2-methoxyethyl acrylate) and investigation of the associated water structure, Macromol. Rapid Commun., 33, 319-325, 2012.
    DOI:10.1002/marc.201100698
  163. T. Hatakeyama, A. Kishi, M. Tanaka, Comparison of measurement techniques for the identification of bound water restrained by polymers, Thermochim Acta, 532, 159-163, 2012.
    DOI:10.1016/j.tca.2011.01.027

    2011
  164. M. Tanaka, Design of Novel 2D and 3D Biointerfaces using Self-Organization to Control Cell behavior, Special issue of Nanotechnologies: Emerging Applications in Biomedicine, Biochimica et Biophysica Acta (BBA) – General Subjects, 1810, 251-258, 2011.
    DOI:10.1016/j.bbagen.2010.10.002
  165. T. Hirata, H. Matsuno, M. Tanaka, K. Tanaka, Surface Segregation of Poly(2-methoxyethyl acrylate) in a Mixture with Poly(methyl methacrylate), Physical Chemistry Chemical Physics, 13, 4928-4934, 2011.
    DOI:10.1039/c0cp02101f
  166. Y. Miwa, M. Tanaka, A. Mochizuki, Analyses of Water structures and dynamics of swollen blood compatible polymers, Koubunshi Ronbunshu, 68, 133-146, 2011.
    DOI:10.1295/koron.68.133

    2010
  167. M. Tanaka, A. Mochizuki, Clarification of the Blood Compatibility Mechanism by Controlling the Water Structure at the Blood–Poly(meth)acrylate Interface, J. Biomat. Sci. Polym. Ed., 21, 1849-1863, 2010.
    DOI:10.1163/092050610X517220
  168. T. Sato, M. Tanaka, S. Yamamoto, E. Ito, K. Shimizu, Y. Igarashi, M. Shimomura, J. Inokuchi, Effect of Honeycomb-Patterned Surface Topography on the Function of Mesenteric Adipocytes, J. Biomat. Sci. Polym. Ed., 21, 1947-1956, 2010.
    DOI:10.1163/092050610X500615
  169. S. Morita, M. Tanaka, K. Kitagawa, Y. Ozaki, Hydration structure of poly(2-methoxyethyl acrylate): comparison with a 2-methoxyethyl acetate model monomer, J. Biomat. Sci. Polym. Ed., 21, 1925-1935, 2010.
    DOI:10.1163/092050610×494613
  170. Y. Miwa, H. Ishida, M. Tanaka, A. Mochizuki, 2H-NMR and 13C-NMR Study of the Hydration Behavior of Poly(2-methoxyethyl acrylate), Poly(2-hydroxyethyl methacrylate) and Poly(tetrahydrofurfuryl acrylate) in Relation to Their Blood Compatibility as Biomaterials, J. Biomat. Sci. Polym. Ed., 21, 1911-1924, 2010.
    DOI:10.1163/092050610X489682
  171. T. Hatakayama, M. Tanaka, H. Hatakayama, Thermal Properties of Freezing Bound Water Restrained by Polysaccharides, J. Biomat. Sci. Polym. Ed., 21, 1865-1875, 2010.
    DOI:10.1163/092050610X486946
  172. A. Mochizuki, M. Kimura, A. Ina, Y. Tomono, M.Tanaka, Study on water structure and blood compatibility of poly(acryloylmorpholine-r-butyl methacrylate), J. Biomat. Sci. Polym. Ed., 21, 1895-1910, 2010.
    DOI:10.1163/092050610X489321
  173. T. Hatakayama, M. Tanaka, H. Hatakayama, Studies on bound water restrained by poly(2-methacryloyloxyethyl phosphorylcholine) (PMPC): Comparison of the polysaccharides-water systems, Acta Biomaterialia, 6, 2077-2082, 2010.
    DOI:10.1016/j.actbio.2009.12.018
  174. H. Ishihata, M. Tanaka, N. Iwama, M. Ara, M. Shimonishi, M. Nagamine, N. Murakami, S. Kanaya, E. Nemoto, H. Shimauchi, M. Shimomura, Proliferation of periodontal ligament cells on biodegradable honeycomb film scaffold with unified micropore organization, Journal of Biomechanical Science and Engineering, Special Issue on Micro and Nanobiotechnology for Cells, 5, 252-261, 2010.
    DOI:10.1299/jbse.5.252
  175. Y. Uraki, C. Matsumoto, T. Hirai, Y. Tamai, M. Enoki, H. Yabu, M. Tanaka, M. Shimomura, Mechanical effect of acetic acid lignin adsorption on honeycomb-patterned cellulosic films, Journal of Wood Chemistry and Technology, 30, 348-359, 2010.
    DOI:10.1080/02773811003746709

    2009
  176. M. Tanaka, M. Takebayashi, M. Shimomura, Fabrication of ordered arrays of biodegradable polymer pincushions using self-organized honeycomb-patterned film, Macromol .Symp., (Invited original paper). 279, 175-182, 2009.
    DOI:10.1002/masy.200950527
  177. M. Tanaka, H. Sato, Y. Sasaya, S. Horinouchi, J. Hotta, Y. Matsuo, K. Ijiro, K. Sasaki, M. Shimomura, Fabrication of Novel Biocompatible Surfaces by Two-Photon Absorption Technique Using Femtosecond Laser, Mol. Cryst. Liq. Cryst., 505, 219-230, 2009.
    DOI:10.1080/15421400902950121
  178. Y. Miwa, H.Ishida, H.Saitô, M. Tanaka, A. Mochizuki, Network structures and dynamics of dry and swollen poly(acrylate)s. Characterization of high- and low-frequency motions as revealed by suppressed or recovered intensities (SRI) analysis of 13C NMR, Polymer, 50, 6091- 6099, 2009.
    DOI:10.1016/j.polymer.2009.10.037
  179. A. Mochizuki, T. Hatakeyama, Y. Tomono, M. Tanaka, Water structure and blood compatibility of poly(tetrahydrofurfuryl acrylate). J. Biomat. Sci. Polym. Ed., 20, 591-603, 2009.
    DOI:10.1163/156856209×426411
  180. A. Mochizuki, A. Kishi, M. Tanaka, Comparative study on water structures in polyHEMA and polyMEA by XRD-DSC simultaneous measurement, J. Appl. Poly. Sci., 111, 476-481, 2009.
    DOI:10.1002/app.29127
  181. Y. M. Chen, J. P. Gong, M. Tanaka, K. Yasuda, S. Yamamoto, M. Shimomura, Y. Osada, Tuning of cell proliferation on tough gels by critical charge effect, J. Biomed. Mater. Res. A, 88A, 74-83, 2009.
    DOI:10.1002/jbm.a.31869
  182. S. Tada, C. Inaba, K. Mizukami, S. Fujishita, M. Gemmei-Ide, H. Kitano, A. Mochizuki, M. Tanaka, T. Matsunaga, Anti-Biofouling Properties of Polymers with a Carboxybetaine Moiety. Macromolecular Bioscience, 9(1), 63-70, 2009.
    DOI:10.1002/mabi.200800150

    2008
  183. M. Tanaka, K. Yoshizawa, A. Tsuruma, H. Sunami, S. Yamamoto, M. Shimomura, Formation of hydroxyapatite on a self-organized 3D honeycomb-patterned biodegradable polymer film, Colloids and Surfaces A: Physicochemical and Engineering Aspects, 313-314, 515-519, 2008.
    DOI:10.1016/j.colsurfa.2007.05.081
  184. K Arai, M. Tanaka, S. Yamamoto, M. Shimomura, Effect of pore size of honeycomb films on the morphology, adhesion and cytoskeletal organization of cardiac myocytes, Colloids and Surfaces A: Physicochemical and Engineering Aspects, 313-314, 530-535, 2008.
    DOI:10.1016/j.colsurfa.2007.04.128
  185. A. Tsuruma, M. Tanaka, S. Yamamoto, M. Shimomura, Control of neural stem cell differentiation on honeycomb films, Colloids and Surfaces A: Physicochemical and Engineering Aspects, 313-314, 536-540, 2008.
    DOI:10.1016/j.colsurfa.2007.05.079
  186. A. Tanabe, S. Morita, M. Tanaka, I. Noda, Y. Ozaki, Multivariate Curve Resolution Analysis on Multi-Component Water Sorption Process into a Poly(2-methoxyethyl acrylate) Film, Appl. Spec., 62, 46-50, 2008.
    DOI:10.1366/000370208783412555
  187. H. Kitano, K. Nagaoka, S. Tada, M. Gemmei-Ide, M. Tanaka, Structure of Water Incorporated in Amphoteric Polymer Thin Films as Revealed by FT-IR Spectroscopy, Macromolecular Bioscience, 8, 77-85, 2008.
    DOI:10.1002/mabi.200700082
  188. Y. Fukuhira, M. Ito, H. Kaneko, Y. Sumi, M. Tanaka, S. Yamamoto, M. Shimomura, Prevention of postoperative adhesions by honeycomb-patterned poly(lactide)film in rat experimental model, J. Biomed. Mater. Res. B, 86B, 353-359, 2008.
    DOI:10.1002/jbm.b.31026
  189. A. Nogami, E. Tominaga, Y. Sawa, T. Murata, Y. Kudo, M.Tanaka, M.Shimomura, Development of the honeycomb film filter for individual aerosol particle analysis, Earozoru Kenkyu, 23(2), 127-133, 2008.
    DOI:10.11203/jar.23.127
  190. S. Tsukiyama, M. Matsushita, M. Tanaka, H. Tamura, S. Todo, S. Yamamoto, M. Shimomura, Enhanced cell survival and yield of rat small hepatocytes by honeycomb-patterned films, Jp. J. Appl. Phys., Vol. 47, No. 2, 1429-1434, 2008.
    DOI:10.1143/JJAP.47.1429
  191. Y. Fukuhira, H. Kaneko, M. Yamaga, M. Tanaka, S. Yamamoto, M. Shimomura, Effect of honeycomb-patterned structure on chondrocyte behavior in vitro, Colloids and Surfaces A: Physicochemical and Engineering Aspects, 313-314, 520-525, 2008.
    DOI:10.1016/j.colsurfa.2007.05.047

    2007
  192. M. Tanaka, A. Takayama, E. Ito, H. Sunami, S. Yamamoto M. Shimomura, Effect of pore size of self-organized honeycomb-patterned polymer films on spreading, focal adhesion, proliferation, and function of endothelial cells, J. Nanosci. Nanotech., 7, 763-772, 2007.
    DOI:10.1166/jnn.2007.514
  193. S. Yamamoto, M. Tanaka, E. Ito, Y. Morita , H. Sunami, K. Ijiro, M. Shimomura, The influence of pore size of a honeycomb film on early spreading process of endtherial cells, J. Surf. Sci. Soc. Jap., 28(8), 433-439, 2007.
    DOI:10.1380/jsssj.28.433
  194. T. Okajima, M. Tanaka, S. Tsukiyama, T. Kadowaki, S. Yamamoto, M. Shimomura, H. Tokumoto, Stress Relaxation and Fluctuation of Living Cells Measured by Atomic Force Microscopy, Jp. J. Appl. Phys., 46 (8B), 5552-5555, 2007.
    DOI:10.1143/JJAP.46.5552
  195. S. Yamamoto, M. Tanaka, H. Sunami, S. Yamashita, Y. Morita, M. Shimomura, Effects of honeycomb-patterned surface topography on the adhesion and signal transduction of porcine aortic endothelial cells, Langmuir, 23, 8114-8120, 2007.
    DOI:10.1021/la700332610.1021/la7003326
  196. J.R. McMillan, M. Akiyama, M. Tanaka, S. Yamamoto, M. Goto, R. Abe, D. Sawamura, M. Shimomura, H. Shimizu, Small-diameter porous poly (epsilon-caprolactone) films enhance adhesion and growth of human cultured epidermal keratinocyte and dermal fibroblast cells., Tissue Engineering, 13, 789-798, 2007.
    DOI:10.1089/ten.2006.0321
  197. Y. M. Chen, M. Tanaka, JP Gong, K Yasuda, S. Yamamoto, M. Shimomura, Y. Osada, Platelet adhesion to human umbilical vein endothelial cells cultured on anionic hydrogel scaffolds, Biomaterials, 28, 1752-1760, 2007.
    DOI:10.1016/j.biomaterials.2006.12.005
  198. T. Okajima, M. Tanaka, S. Tsukiyama, T. Kadowaki, S. Yamamoto, M. Shimomura, H. Tokumoto, Stress relaxation of HepG2 cells measured by atomic force microscopy, Nanotechnology, 18, 084010-4, 2007.
    DOI:10.1088/0957-4484/18/8/084010
  199. S. Morita, M. Tanaka, Y. Ozaki, Time-Resolved In-Situ ATR-IR Observations of Water Sorption Process into a Poly(2-methoxyethyl acrylate) (PMEA) Film, Langmuir, 23, 3750-3761, 2007.
    DOI:10.1021/la0625998
  200. T. Hayashi, M. Tanaka, S. Yamamoto, M. Shimomura, M. Hara, Direct observation of biocompatibility of  PMEA(poly(2-methoxyethyl acrylate)) using Atomic Force Microscopy, Biointerphases, 2(4), 1-9 , 2007.
    DOI:10.1116/1.2794712
  201. S. Morita, M. Tanaka, I. Noda, Y. Ozaki, Phase Angle Description of Perturbation Correlation Analysis and Its Application to Time-Resolved IR Spectra, Appl. Spec.,61(8), 867-872, 2007.
    DOI:10.1366/000370207781540051
  202. E. Hirota, M. Tanaka, A. Mochizuki, Blood Compatibility and Water Structure-Comparative Study between 2-Methoxyethylacrylate- and 2-Methoxyethylmethacrylate-based random copolymers, J. Biomed. Mater. Res. 81A, 710-719, 2007.
    DOI:10.1002/jbm.a.31113
  203. Y. Uraki, J. Nemoto, H. Otsuka, Y. Tamai, J. Sugiyama, T. Kishimoto, M. Ubukata, H. Yabu, M. Tanaka, M. Shimomura, Honeycomb-Like Architecture Produced by Living Bacteria, Gluconacetobacter xylinus, Carbohydrate Polymers, 69, 1-6, 2007.
    DOI:10.1016/j.carbpol.2006.08.021
  204. T. Hatakeyma, H. Kasuga, M. Tanaka, H. Hatakeyama, Cold crystallization of poly(ethylene glycol)-water systems, Thermochim Acta, 465, 59-66, 2007.
    DOI:10.1016/j.tca.2007.09.005

    2006
  205. S. Yamamoto, M. Tanaka, H. Sunami, S. Yamashita, Y. Morita, M. Shimomura, Relationship between adsorbed fibronectin and cell adhesion on a honeycomb-patterned film, Surf. Sci., 600, 3785-3791, 2006.
    DOI:10.1016/j.susc.2006.01.085
  206. M. Tanaka, K. Nishikawa, H. Okubo, H. Kamachi, T. Kawai, M. Matsushita, S. Todo, M. Shimomura, Control of hepatocyte adhesion and function on self-organized honeycomb-patterned polymer film, Colloids and Surfaces A: Physicochemical and Engineering Aspects, 284-285, 464-469, 2006.
    DOI:10.1016/j.colsurfa.2005.11.098
  207. A. Tsuruma, M. Tanaka, S. Yamamoto, N. Fukushima, H. Yabu, M. Shimomura, Topographical control of neurites extension on stripe-patterned polymer films, Colloids and Surfaces A: Physicochemical and Engineering Aspects, 284-285, 470-474, 2006.
    DOI:10.1016/j.colsurfa.2005.11.100
  208. S. Yamamoto, M. Tanaka, H. Sunami, S. Yamashita, Y. Morita, M. Shimomura, Relationship between Adsorbed Fibronectin and Cell Adhesion on a Honeycomb-patterned Film, J. Surf. Sci. Soc. Jap., 27(10), 2006.
    DOI:10.1380/jsssj.27.502
  209. H. Sunami, E. Ito, M. Tanaka, S.Yamamoto, M. Shimomura, Effect of honeycomb film on protein adsorption, cell adhesion and proliferation. Colloids and Surfaces A: Physicochemical and Engineering Aspects, 284-285, 548-551, 2006.
    DOI:10.1016/j.colsurfa.2005.11.041
  210. Y. Fukuhira, E. Kitazono, T. Hayashi, H. Kaneko, M. Tanaka, M. Shimomura, Y. Sumi, Biodegradable honeycomb-patterned film composed of poly(lactic acid) and dioleoylphosphatidylethanolamine, Biomaterials, 27, 1797-1802, 2006.
    DOI:10.1016/j.biomaterials.2005.10.019
  211. E. Hirota, K. Ute, M. Uehara, T. Kitayama, M. Tanaka, A. Mochizuki, -Study of Blood Compatibility with Poly(2-Methoxyethylacrylate) – Relationship between Surface Structure, Water Structure and Platelet Compatibility in 2-Methoxyethylacrylate/2-Hydroxyethylmethacrylate Diblock Copolymer, J. Biomed. Mater. Res., 76A, 540-550, 2006.
    DOI:10.1002/jbm.a.30563
  212. M. Shimomura, A. Tsuruma, M. Tanaka, H. Sunami, S. Yamamoto, Biomedical application of patterned polymer films prepared by self-organization, J. Surf. Sci. Soc. Jap., 27, 170-175, 2006.
    DOI:10.1380/jsssj.27.170

    2005
  213. A. Tsuruma, M. Tanaka, N. Fukushima, M. Shimomura, Morphological changes in neurons by self-organized patterned films, e-J. Surf. Sci. Nanotech., 3, 159-164, 2005.
    DOI:10.1380/ejssnt.2005.159
  214. H. Kitano, T. Mori, Y. Takeuchi, S. Tada, M. Gemmei-ide, Y. Yokoyama, M. Tanaka, Structure of Water Incorporated in Sulfobetaine Polymer Films as Studied by ATR-FTIR, Macromol. Biosci., 5(4), 314-321, 2005.
    DOI:10.1002/mabi.200400212
  215. J. Nemoto, Y. Uraki, T. Kishimoto, Y. Sano, R. Funada, N. Obata, H. Yabu, M. Tanaka, M. Shimomura, Production of mesoscopically patterned cellulose film, Bioresource Technol, 96(17), 1955-1958, 2005.
    DOI:10.1016/j.biortech.2005.01.034
  216. H. Kitano, S. Tada, T. Mori, K. Takaha, M. Gemmei-Ide, M. Tanaka, M. Fukuda, Y. Yokoyama, Correlation between the Structure of Water in the Vicinity of Carboxybetaine Polymers and Their Blood-Compatibility, Langmuir, 21, 11932-11940, 2005.
    DOI:10.1021/la0515571
  217. H. Yabu, M. Takebayashi, M. Tanaka, M. Shimomura, Superhydrophobic and Lipophobic Properties of Self-Organized Honeycomb and Pincushion Structures, Langmuir, 21(8), 3235-3237, 2005.
    DOI:10.1021/la050013w

    2004年以前
  218. M. Tanaka, A. Mochizuki, Effect of water structure on blood compatibility-Thermal analysis of water in poly(meth)acrylate-, J. Biomed. Mater. Res., 68A(3), 684-695, 2004.
    DOI:10.1002/jbm.a.20088
  219. M. Tanaka, Design of Novel BioInterfaces (I) -Blood compatibility of poly(2-methoxyethyl acrylate)-, Bio-Med. Mater. Eng., 14, 427-438, 2004.
    [HTML]
  220. M. Tanaka, M. Takebayashi, M. Miyama, J. Nishida, M. Shimomura, Design of Novel BioInterfaces (II) -Fabrication of self-organized porous polymer film with highly uniform pores-, Bio-Med. Mater. Eng., 14, 439-446, 2004.
    [HTML]
  221. G. Li, S. Morita, S. Ye, M. Tanaka, M. Osawa, Bisphenol QCM and IRRAS Characterization of Bisphenol A Absorption in the Poly(acrylate) Thin Films, Anal. Chem.76, 788-795, 2004.
    DOI:10.1021/ac0348874
  222. A. Tsuruma, M. Tanaka, N. Fukushima, M. Shimomura, Control of neurites extension by self-organized patterned polymer films, Koubunshi Ronbunshuu, 61(12), 628-633, 2004.
    [PDF]
  223.  M. Ide, T. Mori, K. Ichikawa, H. Kitano, M.Tanaka, A. Mochizuki, H. Oshiyama, W. Mizuno, Structure of Water Sorbed into Poly(MEA-co-HEMA) Films As Examined by ATR-IR Spectroscopy, Langmuir, 19, 429-435, 2003.
    DOI:10.1021/la020617p
  224. M. Tanaka, Blood Compatibility of Poly(2-methoxyethyl acrylate) – Design of Novel Biointerfaces, Koubunshi Ronbunshuu, 60(8), 415-427, 2003.
    DOI:10.1295/koron.60.415
  225. S. Ye, S. Morita, G. Li, H. Noda, M. Tanaka, K. Uosaki, M. Osawa, Interfacial Molecular Structure Changes in Poly(2-methoxyethyl acrylate) Thin Films Induced by Absorption of Bisphenol A. An Infrared and Sum Frequency Generation (SFG) Study, Macromolecules, 36, 5694-5703, 2003.
    DOI:10.1021/ma026007d
  226. H. Yabu, M. Tanaka, K. Ijiro, M. Shimomura, Preparation of honeycomb patterned polyimide films by self-organization, Langmuir, 19, 6297-6300, 2003.
    DOI:10.1021/la034454w
  227. M. Tanaka, A. Mochizuki, N. Ishii, T. Motomura, T. Hatakeyama, Study of Blood Compatibility With poly(2-methoxyethyl Acrylate). Relationship Between Water Structure and Platelet Compatibility in poly(2-methoxyethylacrylate-co- 2-hydroxyethylmethacrylate), Biomacromolecules, 3, 36-41, 2002.
    DOI:10.1021/bm010072y
  228. M. Tanaka, A. Mochizuki, T. Shiroya, T. Motomura, K. Shimura, M. Onishi, Y. Okahata, Study on kinetics of early stage protein adsorption on poly(2-methoxyethylacrylate) (PMEA) surface. Colloids and Surfaces A: Physicochemical and Engineering Aspects, 203, 195-204, 2002.
    DOI:10.1016/S0927-7757(01)01100-1
  229. K. Sato, M. Tanaka, K. Hasebe, M. Takebayashi, K. Nishikawa, T. Kawai, M. Matsushita, S. Todo, M. Shimomura, Preparation of the honeycomb patterned porous film of biodegradable polymer for tissue engineering scaffolds, Inter. J. Nanosci., 1(5,6), 689-693, 2002.
    DOI:10.1142/9789812796714_0055
  230. M.Tanaka, A. Mochizuki, T. Motomura, K. Shimura, M. Onishi, Y. Okahata. In Situ Studies on Protein Adsorption onto a Poly(2-methoxyethyl acrylate) Surface by a Quartz Crystal Microbalance. Colloids and Surfaces A: Physicochemical and Engineering Aspects, 193, 145-152, 2001.
    DOI:10.1016/S0927-7757(01)00682-3
  231. H. Kitano, K. Ichikawa, M. Fukuda, A. Mochizuki, M. Tanaka, The Structure of Water Sorbed to Polymethylmethacrylate Film As Examined by FT-IR Spectroscopy, J. Colloid Surface Sci., 242, 133-140, 2001.
    DOI:10.1006/jcis.2001.7785
  232. K. Ichikawa, T. Mori, H. Kitano, M. Fukuda, A. Mochizuki, M. Tanaka, A FT-IR Study on the Sorption of Water to Various Kinds of Polymer Thin Films, J. Polym. Sci., B Polym. Phys. 39, 2175-2182, 2001.
    DOI:10.1002/polb.1191
  233. L. Schiel, S. Burns, A. Nogawa, R. Rice, T. Anzai, M. Tanaka, X-Coating : A New Biopassive Polymer Coating, Canadian Perfusion Canadienne, 11(2), 8-17, 2001.
    [PDF]
  234. M. Tanaka, T. Motomura, N. Ishii, K. Shimura, M. Onishi, A. Mochizuki, T. Hatakeyama, Cold crystallization of water in hydrated Poly(2-methoxyethyl acrylate) (PMEA), Polymer International, 49, 1709-1713, 2000.
    DOI:10.1002/1097-0126(200012)49:12<1709::AID-PI601>3.0.CO;2-L
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