JP KYUSHU UNIVERSITY
Publications

Original Articles

2023

  1. R. Saeki, S. Kobayashi, R. Shimazui, T. Nii, A. Kishimura, M. Tanaka, T. Mori, Y. Katayama, Characterization of polypropyleneimine as an alternative transfection reagent, Analytical Sciences, accepted.
  2. M. Nomura, Y.  Yokoyama, D. Yoshimura, Y. Minagawa, A. Yamamoto, Y. Tanaka, N. Sekiguchi, D. Marukawa, M. Ichihara, H. Itakura, K. Matsumoto, Y. Morimoto, H. Tomihara, A. Inoue, T.  Ogino, N.  Miyoshi, H. Takahashi, H. Takahashi, M. Uemura, S. Kobayashi, T. Mizushima, T.  Anada, M. Mori, Y. Doki, M. Tanaka, H. Eguchi, H. Yamamoto, Simple Detection and Culture of Circulating Tumor Cells from Colorectal Cancer Patients Using Poly(2-Methoxyethyl Acrylate)-Coated Plates, Int. J. Mol. Sci., accepted.
  3. T. Ohta, M. Tanaka, S. Taki, H. Nakagawa, S. Nagase, Honeycomb-like structured film, a novel therapeutic device, suppresses tumor growth in an in vivo ovarian cancer model, Cancers, 15(1), 237 (2023).
    DOI:10.3390/cancers15010237
  4. M. Mabrouk, H. H. Beherei, S. Shiomoto, Y. Tanaka, L. Osama, M. Tanaka, Effect of titanium-doped bioactive glass on poly(2-hydroxyethyl methacrylate) hydrogel composites: bioactivity, intermediate water, cell proliferation, and adhesion forc, Ceramics International, in press.
    DOI: https://doi.org/10.1016/j.ceramint.2022.12.221
  5. C. Kojima, Y. Suzuki, Y. Ikemoto, M. Tanaka, A. Matsumoto, Comparative Study of PEG and PEGylated Dendrimer in their Eutectic Mixtures of Water Analyzed using X-ray Diffraction and Infrared Spectroscopy, Polymer Journal,  55, 63–73 (2023).
    DOI:10.1038/s41428-022-00700-5

    2022
  6. T. Serizawa, S. Yamaguchi, M. Amitani, S. Ishii, H. Tsuyuki, Y. Tanaka, T. Sawada, I. Kawamura, G. Watanabe, M. Tanaka, Alkyl chain length-dependent protein nonadsorption and adsorption properties of crystalline alkyl β-celluloside assemblies, Colloids and Surfaces B: Biointerfaces, 220, 112898 (2022).
    DOI:10.1016/j.colsurfb.2022.112898
  7. S. Kobayashi, A. Sugasaki, Y. Yamamoto, Y. Shigenoi, A. Udaka, A. Yamamoto, M. Tanaka, Enrichment of cancer cells based on antibody-free selective cell adhesion, ACS Biomaterials Science & Engineering, 8(10), 4547-4556 (2022).
    DOI:10.1021/acsbiomaterials.2c00662
  8. J. Park, T. Ueda, Y. Kawai, K. Araki, M. Kido, B. Kure, N. Takenaka, Y. Takashima, M. Tanaka, Simultaneous Control of the Mechanical Properties and Adhesion of Human Umbilical Vein Endothelial Cells to Suppress Platelet Adhesion on a Supramolecular Substrate, RSC Advances, 12(43), 27912-27917 (2022).
    DOI:10.1039/d2ra04885j
  9. M. A. Haque, D. Murakami, M. Tanaka, Cell Adhesion Strength Indicates the Antithrombogenicity of Poly(2-Methoxyethyl Acrylate) (PMEA): Potential Candidate for Artificial Small-Diameter Blood Vessel, Surfaces, 5(3), 365-382 (2022).
    DOI:10.3390/surfaces5030027
  10. Y. Watanabe, S. Takaoka, Y. Haga, K. Kishi, S. Hakozaki, A. Narumi, T. Kato, M. Tanaka, K. Fukushima, Organic carboxylate salt-enabled alternative synthetic routes for bio-functional cyclic carbonates and aliphatic polycarbonates, Polymer Chemistry, 13(36), 5193-5199 (2022).
    DOI:10.1039/d2py00705c
  11. M. A. Haque, D. Murakami, T. Anada, M. Tanaka, Poly(2-methoxyethyl acrylate)(PMEA)-coated anti-platelet adhesive surfaces to mimic native blood vessels through HUVECs attachment, migration, and monolayer formation, Coatings, 12(6), 869 (2022).
    DOI:10.3390/coatings12060869
  12. S. Shiomoto, K. Inoue, H. Higuchi, S. Nishimura, H. Takaba, M. Tanaka, M. Kobayashi, Characterization of Hydration Water Bound to Choline Phosphate-Containing Polymers, Biomacromolecules, 23(7), 2999–3008 (2022).
    DOI:10.1021/acs.biomac.2c00484
  13. M. Mabrouk, H. H. Beherei, Y. Tanaka, M. Tanaka, Sol-gel silicate glass doped with silver for bone regeneration: Antibacterial activity, intermediate water, and cell death mode, Biomaterials Advances, 138, 212965 (2022).
    DOI:10.1016/j.bioadv.2022.212965
  14. J.-J Huang, C.-H. Lin, Y. Tanaka, A. Yamamoto, S.-C Luo, M. Tanaka, Manipulation of Surface Hydration States by Tuning the Oligo(Ethylene Glycol) Moieties on PEDOT to Achieve Platelet-Resistant Bioelectrode Applications, Advanced Materials Interfaces, 2200707 (2022).
    DOI:10.1002/admi.202200707
  15. Y. Ikemoto, Y. Harada, M. Tanaka, S. Nishimura, D. Murakami, N. Kurahashi, T. Moriwaki, K. Yamazoe, H. Washizu, Y. Ishii, H. Torii, Infrared Spectra and Hydrogen-Bond Configurations of Water Molecules at the Interface of Water-Insoluble Polymers under Humidified Conditions, The Journal of Physical Chemistry B, 126(22), 4143-4151 (2022).
    DOI:10.1021/acs.jpcb.2c01702
  16. S. Nishimura, K. Nishida, S. Shiomoto, M. Tanaka, Surfactant-Free Suspension Polymerization of Hydrophilic Monomers with an Oil-in-Water System for the Preparation of Microparticles Toward the Selective Isolation Tumor Cells, Materials Advances, 3(12), 5043-5054 (2022).
    DOI:10.1039/D2MA00129B
  17. K. Nishida, T. Anada, M. Tanaka, Roles of interfacial water states on advanced biomedical material design, Advanced Drug Delivery Reviews, 186, 114310 (2022).
    DOI:10.1016/j.addr.2022.114310
  18. K. Nishida, K. Baba, D. Murakami, M. Tanaka, Nanoscopic Analyses of Protein Adsorption on Poly(2-methoxyethyl acrylate) Surfaces for Tailoring Cell Adhesiveness, Biomaterials Science, 10(11), 2953-2963 (2022).
    DOI:10.1039/D2BM00093H
  19. S. Nishimura, K. Nishida, T. Ueda, S. Shiomoto, M. Tanaka, Biocompatible poly(N-(ω-acryloyloxy-n-alkyl)-2-pyrrolidone)s with widely-tunable lower critical solution temperatures (LCSTs): a promising alternative to poly(N-isopropylacrylamide), Polymer Chemistry, 13(17), 2519–2530 (2022).
    DOI:10.1039/d2py00154c
  20. M. Hishida, R. Anjum, T. Anada, D. Murakami, M. Tanaka, Effect of Osmolytes on Water Mobility Correlates with Their Stabilizing Effect on Proteins, The Journal of Physical Chemistry B, 126, 13, 2466–2475(2022).
    DOI:10.1021/acs.jpcb.1c10634
  21. T. Tominaga, M. Hishida, D. Murakami, Y. Fujii, M. Tanaka, H. Seto, Experimental Evidences of Slow Mode Water in the Vicinity of Polyethylene oxide at Physiological Temperature, The Journal of Physical Chemistry B, 126, 8, 1758–1767 (2022).
    DOI:10.1021/acs.jpcb.1c09044
  22. K. Nishida, S. Nishimura, M. Tanaka, Selective Accumulation To Tumor Cells With Coacervate Droplets Formed From Water-Insoluble Acrylate Polymer, Biomacromolecules, 23(4), 1569–1580 (2022).
    DOI:10.1021/acs.biomac.1c01343
  23. K. Nishida, S. Sekida, T. Anada, M. Tanaka, Modulation of biological responses of tumor cell adhering to poly(2-methoxyethyl acrylate) with increasing cell viability under serum-free conditions, ACS Biomaterials Science & Engineering, 8(2), 672–681 (2022).
    DOI:10.1021/acsbiomaterials.1c01469
  24. D. Murakami, K. Yamazoe, S. Nishimura, N. Kurahashi, T. Ueda, J. Miyawaki, Y. Ikemoto, M. Tanaka, Y. Harada, Hydration Mechanism in Blood-compatible Polymers Undergoing Phase Separation, Langmuir, 38(3), 1090-1098 (2022).
    DOI:10.1021/acs.langmuir.1c02672
  25. D. Murakami, S. Nishimura, Y. Tanaka, M. Tanaka, Observing the Repulsion Layers on Blood-compatible Polymer-grafted Interfaces by Frequency Modulation Atomic Force Microscopy, Biomaterials Advances, 133, 112596 (2022).
    DOI:10.1016/j.msec.2021.112596
  26. K. Fukushima, K. Matsuzaki, M. Oji, Y. Higuchi, G. Watanabe, Y. Suzuki, M. Kikuchi, N. Fujimura,  N. Shimokawa, H. Ito, T. Kato, S. Kawaguchi, M. Tanaka, Anisotropic, Degradable Polymer Assemblies Driven by a Rigid Hydrogen-Bonding Motif That Induce Shape-Specific Cell Responses, Macromolecules, 55(1), 15–25 (2022).
    DOI:10.1021/acs.macromol.1c01894
  27. S. Nishimura, K. Nishida, M. Tanaka, A β-Hairpin Peptide with pH-Controlled Affinity for Tumor Cells, Chem. Commun., 58(4), 505-508 (2022).
    DOI:10.1039/D1CC06218B
  28. R. Koguchi, K. Jankova, M. Tanaka, Fluorine-Containing Bio-Inert Polymers –Roles of Intermediate Water, Acta Biomaterialia, 138, 34-56 (2022).
    DOI:10.1016/j.actbio.2021.10.027
  29. C. Ueda, J. Park, K. Hirose, S. Konishi, Y. Ikemoto, M. Osaki, H. Yamaguchi, A. Harada, M. Tanaka, G. Watanabe, Y. Takashima, Behavior of Supramolecular Cross-Links Formed by Host-Guest Interaction in Hydrogels Responding to Water Contents, Supramolecular Materials, 1, 100001 (2022).
    DOI:10.1016/j.supmat.2021.100001

    2021
  30. Y. Asawa, K. Nishida, K. Kawai, K. Domae, H. S. Ban, A. Kitazaki, H. Asami, J. Kohno, S. Okada, H. Tokuma, D. Sakano, S. Kume, M. Tanaka, H. Nakamura, Carborane as an Alternative Efficient Hydrophobic Tag for Protein Degradation, Bioconjugate Chem., 32(11), 2377–2385 (2021).
    DOI:10.1021/acs.bioconjchem.1c00431
  31. W. Lee, S.-H. Jeong, Y.-W. Lim, H. Lee, J. Kang, H. Lee, l. Lee, H-S. Han, S. Kobayashi, M. Tanaka, B.-S. Bae, Conformable Microneedle pH Sensors via the Integration of two Different Siloxane Polymers for Mapping Peripheral Artery Disease, Science Advances, 7(48), eabi6290 (2021).
    DOI:10.1126/sciadv.abi6290
  32. T. Ishizawa, N. Makino, Y. Kakizaki, A. Matsuda, Y. Toyokawa, S. Ooyama, M. Tanaka, Y. Ueno, Biosafety of a novel covered self-expandable metal stent coated with poly(2-methoxyethyl acrylate) in vivo, PLoS ONE, 16(9), e0257828 (2021).
    DOI:10.1371/journal.pone.0257828
  33. R. Chang, E. Angelo Q. Mondarte, D. Palai, T. Sekine, A. Kashiwazaki, D. Murakami, M. Tanaka, T. Hayashi, Protein- and cell-resistance of zwitterionic peptide-based self-assembled monolayers: anti-biofouling tests and surface force analysis, Frontiers in Chemistry, 9, 748017 (2021). 
    DOI:10.3389/fchem.2021.748017
  34. Y. Fujii, T. Tominaga, D. Murakami, M. Tanaka, H. Seto, Local Dynamics of the Hydration Water and Poly(Methyl Methacrylate) Chains in PMMA Networks, Frontiers in Chemistry, 9, 728738 (2021).
    DOI:10.3389/fchem.2021.728738
  35. M. Osaki, S. Yonei, C. Ueda, R. Ikura, J. Park, H. Yamaguchi, A. Harada, M. Tanaka, Y. Takashima, Mechanical Properties with Respect to Water Content of Host-Guest Hydrogels, Macromolecules, 54(17), 8067–8076(2021).
    DOI:10.1021/acs.macromol.1c00970
  36. T. Ueda, D. Murakami, M. Tanaka, Effect of Amount of Hydrated Water and Mobility of Hydrated Poly(2-Methoxyethyl Acrylate) on Denaturation of Adsorbed Fibrinogen, Journal of Polymer Science, 59, 2763-2770 (2021).
    DOI:10.1002/pol.20210496
  37. K. Nishida, T. Anada, S. Kobayashi, T. Ueda, M. Tanaka, Effect of bound water content on cell adhesion strength to water-insoluble polymers, Acta Biomaterialia, 134, 313-324(2021).
    DOI:10.1016/j.actbio.2021.07.058
  38. M. Mabrouk, H.H. Beherei, Y. Tanaka, M. Tanaka, Investigating the Intermediate Water Feature of Hydrated Titanium Containing Bioactive Glass, Int. J. Mol. Sci., 22(15), 8038, (2021).
    DOI:10.3390/ijms22158038
  39. S. Liu, S. Kobayashi, S. Nishimura, T. Ueda, M. Tanaka, Effect of Pendant Groups on the Blood Compatibility and Hydration States of Poly(2-oxazoline)s, Journal of Polymer Science, 2559-2570 (2021).
    DOI:10.1002/pol.20210410
  40. R. Anjum, S. Nishimura, S. Kobayashi, K. Nishida, T. Anada, M. Tanaka, Protein Stabilization Effect of Zwitterionic Osmolyte-bearing Polymer, Chemistry Letters, 50(9), 1699-1702(2021).
    DOI:10.1246/cl.210335
  41. M. Yamazaki, Y. Sugimoto, D. Murakami, M. Tanaka, T. Ooya, Effect of Branching Degree of Dendritic Polyglycerols on Plasma Protein Adsorption: Relationship Between Hydration States and Surface Morphology, Langmuir, 37(28), 8534–8543 (2021).
    DOI:10.1021/acs.langmuir.1c01003
  42. T. Kanamaru, M. Araki, R. Takahashi, S. Fujii, T. Shikata, D. Murakami, M. Tanaka, K. Sakurai, The first observation of the hydration layer around polymer chain by scattering and its relationship to thromboresistance; dilute solution properties of PMEA in THF/water, The Journal of Physical Chemistry B, 125(26), 7251–7261 (2021).
    DOI:10.1021/acs.jpcb.1c01864
  43. C. Yoshikawa, S. Hattori, C-F. Huang, H. Kobayashi, M. Tanaka, In vitro and In vivo Blood Compatibility of Concentrated Polymer Brushes, Journal of Materials Chemistry B, 9, 5794-5804 (2021).
    DOI:10.1039/D1TB00886B
  44. S. Liu, S. Kobayashi, T. Sonoda, M. Tanaka, Poly(tertiary amide acrylate) (Co)polymers Inspired by Poly(2-oxazoline)s: Their Blood Compatibility and Hydration States, Biomacromolecules, 22(6), 2718-2728 (2021).
    DOI:10.1021/acs.biomac.1c0041
  45. A. T. Kuo, S. Urata, R. Koguchi, T. Sonoda, S. Kobayashi, M. Tanaka, Effects of Side-Chain Spacing and Length on Hydration States of the Poly(2-methoxyethyl acrylate) Analogs: A Molecular Dynamics Study, ACS Biomaterials Science & Engineering, 7(6), 2383-2391 (2021).
    DOI:10.1021/acsbiomaterials.1c00388
  46. A. Tsujimoto, H. Uehara, H. Yoshida, M. Nishio, K. Furuta, T. Inui, A. Matsumoto, S. Morita, M. Tanaka, C. Kojima, Different Hydration States and Passive Tumor Targeting Ability of Polyethylene Glycol-modified Dendrimers with High and Low PEG density, Materials Science & Engineering C, 126, 112159 (2021).
    DOI:10.1016/j.msec.2021.112159
  47. R. Anjum, K. Nishida, H. Matsumoto, D. Murakami, S. Kobayashi, T. Anada, M. Tanaka, Attachment and Growth of Fibroblast Cells on Poly(2-methoxyethyl acrylate) Analog Polymers as Coating Materials, Coatings, 11(4), 461(2021).
    DOI:10.3390/coatings11040461
  48. S. Nishimura, T. Ueda, D. Murakami, M. Tanaka, Chain End Effect for Intermediate Water Formation of Poly(2-methoxyethyl acrylate), Organic Materials, 03(02), 214-220(2021).
    DOI:10.1055/a-1441-8239
  49. T. Sonoda, S. Kobayashi, M. Tanaka, Periodically Functionalized Linear Polyethylene with Tertiary Amino Groups via Regioselective Ring-Opening Metathesis Polymerization, Macromolecules, 54(6), 2862–2872 (2021).
    DOI:10.1021/acs.macromol.0c02611
  50. V. Montagna, J. Takahashi, M-Y. Tsai, T. Ota, N. Zivic, S. Kawaguchi, T. Kato, M. Tanaka, H. Sardón, K. Fukushima, Methoxy-Functionalized Glycerol-Based Aliphatic Polycarbonate: Organocatalytic Synthesis, Blood Compatibility, and Hydrolytic Property, ACS Biomaterials Science & Engineering, 7(2), 472–481 (2021).
    DOI:10.1021/acsbiomaterials.0c01460
  51. Y. Toyokawa, S. Kobayashi, H. Tsuchiya, T. Shibuya, M. Aoki, J. Sumiya, S. Ooyama, T. Ishizawa, N. Makino, Y. Ueno, M. Tanaka, A fully covered self-expandable metallic stent coated with poly (2-methoxyethyl acrylate) and its derivative: In vitro evaluation of early-stage biliary sludge formation inhibition, Materials Science & Engineering C, 120, 111386 (2021).
    DOI: 1016/j.msec.2020.111386
  52. T. Ueda, D. Murakami, M. Tanaka, Effect of Interfacial Structure Based on Grafting Density of Poly(2-Methoxyethyl Acrylate) on Blood Compatibility, Colloids and Surfaces B: Biointerfaces, 199, 111517 (2021) .
    DOI:10.1016/j.colsurfb.2020.111517
  53. M. Tanaka, S. Morita, T. Hayashi, Role of Interfacial Water in Determining the Interaction of Proteins and Cells with Hydrated Materials, Colloids and Surfaces B: Biointerfaces, 198, 111449 (2021).
    DOI:10.1016/j.colsurfb.2020.111449

    2020
  54. K. Athanasopulu, D. Caltzidou, A. Sekishita, L. Kutuzova, G. Lorenz, M. Tanaka, R.  Kemkemer,  Sulfated Hyaluronan coating of polyurethanebased implant materials, Current Directions in Biomedical Engineering, 6(3), 20203115 (2020).
    DOI:10.1515/cdbme-2020-3115
  55. A.T. Kuo, S. Urata, R. Koguchi, T. Sonoda, S. Kobayashi, M. Tanaka, Molecular Dynamics Study on the Water Mobility and Side-chain Flexibility of Hydrated Poly(ω-methoxyalkyl acrylate)s, ACS Biomaterials Science & Engineering, 6(12), 6690-6700 (2020).
    DOI:10.1021/acsbiomaterials.0c01220
  56. T. Sonoda, S. Kobayashi, K. Herai, M. Tanaka, Side chain spacing control of derivatives of poly(2-methoxyethyl acrylate): impact on hydration states and antithrombogenicity, Macromolecules, 53, 8570-8580 (2020).
    DOI: 10.1021/acs.macromol.0c01144
  57. S. Nishimura, T. Ueda, S. Kobayashi, M. Tanaka, Silsesquioxane/Poly(2-methoxyethyl acrylate) Hybrid with Both Antithrombotic and Endothelial Cell Adhesive Properties, ACS Applied Polymer Materials, 2, 4790-4801 (2020) (Front Cover in this issue).
    DOI: 10.1021/acsapm.0c00776
  58. A.T. Kuo, T. Sonoda, S. Urata, R. Koguchi, S. Kobayashi, M. Tanaka, Elucidating the Feature of Intermediate Water in Hydrated Poly(ω-methoxyalkyl acrylate)s by Molecular Dynamics Simulation and Differential Scanning Calorimetry Measurement, ACS Biomater. Sci. Eng., 6(7), 3915-3924 (2020).
    DOI: 10.1021/acsbiomaterials.0c00746
  59. R. Koguchi, K. Jankova, Y. Hayasaka, D. Kobayashi, Y. Amino, T. Miyajima, S. Kobayashi, D. Murakami, K. Yamamoto, M. Tanaka, Understanding the effect of hydration on the bio-inert properties of HEMA copolymers with small amounts of amino- or/and fluorine-containing monomers, ACS Biomater. Sci. Eng., 6, 2855-2866 (2020).
    DOI: 10.1021/acsbiomaterials.0c00230
  60. M-Y. Tsai, F. Aratsu, S. Sekida, S. Kobayashi, M. Tanaka, Blood-compatible poly(2-methoxyethyl acrylate) induces blebbing-like phenomenon and promotes viability of tumor cells in serum-free medium, ACS Applied Bio Materials, 3, 1858-1864 (2020).
    DOI: 10.1021/acsabm.9b00885
  61. D. Murakami, Y. Segami, T. Ueda, M. Tanaka, Control of interfacial structures and anti-platelet adhesion property of blood-compatible random copolymers, J. Biomater. Sci. Polym. Ed., 31, 207-218 (2020).
    DOI: 10.1080/09205063.2019.1680930
  62. M. Watanabe, Y. Tanaka, D. Murakami, M. Tanaka, M. Kawai, T. Mitsumata, Optimal plasticizer content for magnetic elastomers used for cell culture, Chemistry Letters, 49, 280-283 (2020).
    DOI: 10.1246/cl.190929

    2019
  63. R. Sakamoto, K. Nakamoto, A. Kitajo, D. Murakami, H. Hirai, M. Tanaka, Y.Zhou, T. Yamaguchi, S. Okada, Highly Concentrated Aqueous Electrolytes for Building High Voltage Aqueous Batteries, The Electrochemical Society of Japan, 87(Autumn), 220-226 (2019).
    DOI: 10.5796/denkikagaku.19-FE0022
  64. M. Tanaka, S. Kobayashi, D. Murakami, F. Aratsu, A. Kashiwazaki, T. Hoshiba, K. Fukushima, Design of Polymeric Biomaterials: The “Intermediate Water Concept”, Bull. Chem. Soc. Jpn., 92, 2043-2057 (2019).
    DOI: 10.1246/bcsj.20190274
  65. K. Jankova, I. Javakhishvili, S. Kobayashi, R. Koguchi, D. Murakami, T. Sonoda, M. Tanaka, Hydration states and blood compatibility of Hydrogen-bonded supramolecular poly(2-methoxyethyl acrylate), ACS Appl. Bio Mater., 2, 4154-4161 (2019).
    DOI: 10.1021/acsabm.9b00363
  66. T. Araki, F. Yoshida, T. Uemura, Y. Noda, S. Yoshimoto, T. Kaiju, T. Suzuki, H. Hamanaka, K. Baba, H. Hayakawa, T. Yabumoto, H. Mochizuki, S. Kobayashi, M. Tanaka, M. Hirata, T. Sekitani, Long-term implantable, flexible, and transparent neural interface based on Ag/Au core-shell nanowires, Adv. Healthcare Mater., 8, 1900130 (2019).
    DOI: 10.1002/adhm.201900130
  67. R. Koguchi, K. Jankova, N. Tanabe, Y. Amino, Y. Hayasaka, D. Kabayashi, T. Miyajima, K. Yamamoto, M. Tanaka, Controlling the hydration structure with small amount of fluorine to produce blood compatible fluorinated poly(2-methoxyethyl acrylate), Biomacromolecules, 20, 2265-2275 (2019).
    DOI: 10.1021/acs.biomac.9b00201
  68. A.-T. Kuo, S. Urata, R. Koguchi, K. Yamamoto, M. Tanaka, Analyses of Equilibrium Water Content and Blood Compatibility for Poly(2-methoxyethyl acrylate) by Molecular Dynamics Simulation, Polymer, 170, 76-84 (2019).
    DOI: 10.1016/j.polymer.2019.03.001
  69. M. Okada, E. Hara, D. Kobayashi, S. Kai, K. Ogura, M. Tanaka, T. Matsumoto, Intermediate water on calcium phosphate minerals: its origin and role in crystal growth, ACS Applied Bio Materials, 2, 981-986 (2019).
    DOI: 10.1021/acsabm.9b00014
  70. D. Murakami, N. Mawatari, T. Sonoda, A. Kashiwazaki, M. Tanaka, Effect of Molecular Weight of Poly(2-methoxyethylacrylate) on Interfacial Structure and Blood Compatibility. Langmuir, 35, 2808-2813 (2019).
    DOI: 10.1021/acs.langmuir.8b02971

    2018
  71. W. Lee, S. Kobayashi, M. Nagase, Y. Jimbo, I. Saito, Y. Inoue, T. Yambe, M. Sekino, G. G Malliaras, T. Yokota, M. Tanaka, T. Someya, A Nonthrombogenic, Stretchable, Active Multielectrode Array using Organic Electrochemical Transistors, Science Advances, 4(10), eaau2426 (2018).
    DOI: 10.1126/sciadv.aau2426
  72. T. Ueda, D. Murakami, M. Tanaka, Analysis of interaction between interfacial structure and fibrinogen at blood-compatible polymer/water interface. Frontiers in Chemistry, Polymer Surface Chemistry: Biomolecular Engineering and Biointerfaces, 6, 542 (2018).
    DOI: 10.3389/fchem.2018.00542
  73. F. Khan, F. Aratsu, S. Kobayashi, M. Tanaka, A Simple Strategy for Robust Hydrogel Preparation and Characterisation Derived from Chitosan and Amino Functional Monomers for Biomedical Applications, Journal of Materials Chemistry B, 6, 5115-5129 (2018).
    DOI: 10.1039/C8TB00865E
  74. D. Murakami, Y. Kitahara, S. Kobayashi, M. Tanaka, Thermosensitive Polymer Biocompatibility based on Interfacial Structure at Biointerface, ACS Biomaterials Science & Engineering, 4, 1591-1597 (2018). 
    DOI: 10.1021/acsbiomaterials.8b00081
  75. M. Mabrouk, H. H.  Beherei, S. ElShebiney, M. Tanaka, Newly developed controlled release subcutaneous formulation for tramadol hydrochloride, Saudi Pharmaceutical Journal, 26, 585-592 (2018).
    DOI: 10.1016/j.jsps.2018.01.014
  76. F. Khan, M. Tanaka, Designing Smart Biomaterials for Tissue Engineering, International Journal of Molecular Sciences, 19(1), 17 (2018). 
    DOI: 10.3390/ijms19010017
  77. T. Hoshiba, K. Sato, N. Kawazoe, G. CHEN, M. Tanaka, Chondrocyte shapes and detachment on a thermo-responsive poly (2-methoxyethyl acrylate) analog for the development of new chondrocytes subculture substrate, Chemistry Letters, 47(1), 107-109 (2018).
    DOI: 10.1246/cl.170889

    2017
  78. S. Kobayashi, M. Wakui, Y. Iwata, M. Tanaka, Poly(ω-methoxyalkyl acrylate)s: A nonthrombogenic polymer family with tunable protein adsorption, Biomacromolecules, 18 (12), 4214-4223 (2017).
    DOI: 10.1021/acs.biomac.7b01247
  79. K. Fukushima, Y. Inoue, Y. Haga, T. Ota, K. Honda, C. Sato, M. Tanaka, Monoether-tagged Biodegradable Polycarbonate Preventing Platelet Adhesion and Demonstrating Adhesion of Vascular Cells: A Promising Material for Resorbable Vascular Grafts and Stents, Biomacromolecules, 18 (11), 3834–3843 (2017).
    DOI: 10.1021/acs.biomac.7b01210
  80. T. Hoshiba, H. Maruyama, K. Sato, C. Endo, N. Kawazoe, G. Chen, M. Tanaka, Maintenance of Cartilaginous Gene Expression of Serially Subcultured Chondrocytes on Poly(2-Methoxyethyl Acrylate) Analogous Polymers, Macromol. Biosci.,17,170297(2017) .
    DOI: 10.1002/mabi.201700297
  81. K. Fukushima, K. Honda, Y. inoue, M. Tanaka, Synthesis of Antithrombotic Poly(carbonate-urethane)s through a Sequential Process of Ring-Opening Polymerization and Polyaddition Facilitated by Organocatalysts, Eur. Polym. J., Vol. 95,  728-736 (2017).
    DOI: 10.1016/j.eurpolymj.2017.07.001
  82. K. Sato, S. Kobayashi, A. Sekishita, M. Wakui, M. Tanaka, Synthesis and Thrombogenicity Evaluation of Poly(3-methoxypropionic acid vinyl ester): a candidate for blood compatible polymer, Biomacromolecules, 18, 1609-1616 (2017).
    DOI: 10.1021/acs.biomac.7b00221
  83. T. Hoshiba, A.Yoshihiro, M. Tanaka, Evaluation of initial cell adhesion on poly (2-methoxyethyl acrylate) (PMEA) analogous polymers, J. Biomat. Sci. Polym. Ed., 28, 986-999 (2017).
    DOI: 10.1080/09205063.2017.1312738
  84. T. Sekine, S. Asatyas, C. Sato, S. Morita, M. Tanaka, T. Hayashi, Surface force and vibrational spectroscopic analyses of interfacial water molecules in the vicinity of methoxy-tri(ethylene glycol)-terminated monolayers: mechanisms underlying the effect of lateral packing density on bioinertness, J. Biomat. Sci. Polym. Ed., 28, 1231-1243 (2017).
    DOI: 10.1159/000451043
  85. Y. Inoue,  T. Yokota, T. Sekitani, A. Kaneko, T. Woo, S. Kobayashi, T.Shibuya, M. Tanaka, H. Koshukegawa, I. Saito, T. Isoyama, Y. Abe, T.Yambe, T. Someya, M. Sekino, Antithrombotic Protein Filter Composed of Hybrid Tissue-Fabric Material has a Long Lifetime, Annals of Biomedical Engineering, 45(5), 1352-1364 (2017).
    DOI: 10.1007/s10439-016-1781-5
  86. T. Hirata, H. Matsuno, D. Kawaguchi, M. Inutsuka, T. Hirai, M. Tanaka, K. Tanaka, Dynamics of a bioinert polymer in hydrated states by dielectric relaxation spectroscopy, Physical Chemistry Chemical Physics, 19,1389-1394 (2017).
    DOI: 10.1039/c6cp07322k

    2016
  87. T. Hoshiba, E. Nemoto, K. Sato, H. Maruyama, C. Endo, M. Tanaka, Promotion of adipogenesis of 3T3-L1 cells on protein adsorption-suppressing poly (2-methoxyethyl acrylate) analogous polymers, Biomacromolecules, 17,3808-3815 (2016).
    DOI:10.1021/acs.biomac.6b01340
  88. D. Murakami, S. Kobayashi, M. Tanaka, Interfacial Structures and Fibrinogen Adsorption at Blood-Compatible Polymer/Water Interfaces, ACS Biomater. Sci. Eng., 2, 2122–2126 (2016).
    DOI:0.1021/acsbiomaterials.6b00415
  89. K. Osawa, S. Kobayashi, M. Tanaka, Synthesis of Sequence-Specific Polymers with Amide Side-chains via Regio-/stereoselective Ring-opening Metathesis Polymerization of 3-Substituted cis-Cycloocte, Macromolecules, 49, 8154-8161 (2016).
    DOI:10.1021/acs.macromol.6b01829
  90. T. Hoshiba, M. Tanaka, Integrin-independent cell adhesion substrates:Possibility of applications for mechanobiology research, Special Issue:Mechanobiology, Analytical Sciences, 32,1151-1158 (2016).
    DOI:10.1021/acs.macromol.6b01829
  91. T. Hoshiba, T. Orui, C. Endo, K. Sato, A. Yoshihiro, Y. Minagawa, M.Tanaka, Adhesion-Based Simple Capture and Recovery of Circulating Tumor Cells Using a Blood-Compatible and Thermo-Responsive Polymer-Coated Substrate, RSC Advances, 6, 89103-89112 (2016).
    DOI:10.1039/C6RA15229E
  92. A. Basterretxea, Y. Haga, A. Sanchez-Sanchez, M. Isik, L. Irusta, M. Tanaka, K. Fukushima, H. Sardon, Biocompatibility and hemocompatibility evaluation of polyether urethanes synthesized using DBU organocatalyst, Eropean Polymer Journal, 84, 750-758 (2016).
    DOI:10.1016/j.eurpolymj.2016.08.008
  93. T. Hoshiba, M.Tanaka, Decellularized matrices as in vitro models of extracellular matrix in tumor tissues at different malignant levels:Mechanism of 5-fluorouracil resistance in colorectal tumor cells, BBA - Molecular Cell Research, 1863,2749-2757 (2016).
    DOI:10.1016/j.bbamcr.2016.08.009.
  94. K. Kono, H. Hiruma, S. Kobayashi, Y. Sato,  M.Tanaka, R. Sawada, S. Niimi, In vitro endothelialization test of biomaterials using immortalized endothelial cells, PLoS One, 11(6), e01582898 (2016).
    DOI:10.1371/journal.pone.0158289
  95. S. Kobayashi, K. Fukuda, M. Kataoka, M. Tanaka, Regioselective Ring-Opening Metathesis Polymerization of 3-Substituted Cyclooctenes with Ether Side-Chains, Macromolecules, 49(7), 2493-2501 (2016).
    DOI:10.1021/acs.macromol.6b00273
  96. C. Sato, M. Aoki, M. Tanaka, Blood-compatible poly(2-methoxyethyl acrylate) for the adhesion and proliferation of endothelial and smooth muscle cells, Colloids and Surfaces B: Biointerfaces,145, 586-596 (2016).
    DOI:10.1016/j.colsurfb.2016.05.057
  97. T. Hoshiba, M. Nikaido, S.Yagi, I. Konno, A. Yoshihiro, M. Tanaka, Blood-compatible poly (2-methoxyethyl acrylate) for the adhesion and proliferation of lung cancer cells toward the isolation and analysis of circulating tumor cells, Journal of Bioactive and Compatible Polymers, 31, 361-372 (2016).
    DOI:10.1177/0883911515618976
  98. H. Choi, M. Tanaka, K. Sugimoto, Difference in cell proliferation and spontaneous mediator release between two mast cell lines, NCL-2 and RBL-2H3 on honeycomb-like structured film, Journal of Nanotechnology: Nanomedicine & Nanobiotechnology, 3(009) (2016).
    DOI:10.24966/NTMB-2044/100009
  99.  T. Hoshiba, G. Chen, C. Endo, H. Maruyama, M. Wakui, E. Nemoto, N. Kawazoe, M. Tanaka. Decellularized extracellular matrix (ECM) as an in vitro model to study the comprehensive roles of the ECM in stem cell differentiation. Stem Cells Int., 2016, 6397820 (2016).
    DOI:10.1155/2016/6397820

    2015
  100. T. Hoshiba, T. Otaki, E. Nemoto, H. Maruyama, M. Tanaka. Blood compatible polymer for hepatocyte culture with high hepatocyte-specific functions toward bioartificial liver development. ACS Appl. Mater. Interfaces 7, 18096-18103 (2015).
    DOI:10.1021/acsami.5b05210
  101. T. Hirata, H. Matsuno, D. Kawaguchi, N. Yamada, M. Tanaka, K. Tanaka, Construction of a blood-compatible interface based on surface segregation in a polymer blend, Polymer, 78, 219-224 (2015).
    DOI:10.1016/j.polymer.2015.10.001
  102. F. Khan, M. Tanaka, S.R. Ahmad, Fabrication of polymeric biomaterials: a strategy for tissue engineering and medical devices, Journal of Materials Chemistry B, 3, 8224-8249 (2015).
    DOI:10.1039/C5TB01370D
  103. T. Hoshiba, E. Nemoto, K. Sato, T. Orui, T. Otaki, A. Yoshihiro, M. Tanaka. Regulation of the contribution of integrin to cell attachment on poly(2-methoxyethyl acrylate) (PMEA) analogous polymers for attachment-based cell enrichment. PLoS One,10, e0136066 (2015).
    DOI:10.1371/journal.pone.0136066
  104. T. Sekine, Y. Tanaka, C. Sato, M. Tanaka, T. Hayashi, Evaluation of factors to determine platelet compatibility by using self-assembled monolayers with a chemical gradient, Langmuir, 31,7100-7105 (2015).
    DOI:10.1021/acs.langmuir.5b01216
  105. K. Sato, S. Kobayashi, M. Kusakari, S. Watahiki, M. Oikawa, T. Hoshiba,  M. Tanaka, The relationship between water structure and blood compatibility in poly(2-methoxyethyl acrylate) (PMEA) analogues, Macromol. Biosci., 15, 1296-1303 (2015).
    DOI:10.1002/mabi.201500078
  106.  T. Hirata, H. Matsuno, D. Kawaguchi, N. Yamada, M. Tanaka, K. Tanaka, Effect of interfacial structure on bioinert property of poly(2-methoxyethyl acrylate)/ poly(methyl methacrylate) blend films in water, Phys. Chem. Chem. Phys., 17,17399-17405 (2015).
    DOI:10.1039/c5cp01972a
  107. K. Fukushima, M. Tsai, T. Ota, Y. Haga, K. Matsuzaki, Y. Inoue, M. Tanaka, Evaluation of the hemocompatibility of hydrated biodegradable aliphatic carbonyl polymers with a subtle difference in the backbone structure based on the intermediate water concept and surface hydration, Polym. J., 47, 469-473 (2015). 
    DOI:10.1038/pj.2015.22
  108. T. Hirata, H. Matsuno, D. Kawaguchi, T. Hirai, N. Yamada, M. Tanaka, K. Tanaka, Effect of Local Chain dynamics on a Bio-inert Interface, Langmuir, 31, 3661-3667 (2015).
    DOI:10.1021/acs.langmuir.5b00258
  109. M. Tanaka, K. Sato, E. Kitakami, S. Kobayashi, T. Hoshiba, K. Fukushima, Design of biocompatible and biodegradable polymers based on the intermediate water concept, Polymer Journal, 47, 114-121 (2015). Invited paper: Special Issue on Fusion Materials, Most Accessed Papers(September - December 2015)
    DOI:10.1038/pj.2014.129
  110. T. Hoshiba, M. Tanaka, Optimization of the tissue source, malignancy, and initial substrate of tumor cell-derived matrices to increase cancer cell chemoresistance against 5-fluorouracil. Biochem. Biophys.Res. Commun., 457, 353-357 (2015).
    DOI:10.1016/j.bbrc.2014.12.116

    2014
  111. S. Morita, M. Tanaka, Effect of Sodium Chloride on Hydration Structures of PMEA and P(MPC-r-BMA), Langmuir, 30,10698-10703 (2014).
    DOI:10.1021/la502550d
  112. K. Sugimoto, H. Choi, M. Tanaka, Honeycomb-like structured film regulates mediator release from non-tumor mast cells,  European Journal of Inflammation, 12, 515-520 (2014).
    DOI:10.1177/1721727X1401200313
  113. E. Kitakami, M. Aoki, C. Sato, H. Ishihata, M. Tanaka, Adhesion and proliferation of human periodontal ligament cells on poly(2-methoxyethyl acrylate), BioMed Resarch International, 2014, 102648 (2014).
    DOI:10.1155/2014/102648
  114. T. Hoshiba, M. Nikaido, M. Tanaka, Characterization of the Attachment Mechanisms of Tissue-Derived Cell Lines to Blood-Compatible Polymers, Adv. Healthcare Mater., 3, 775-784 (2014).
    DOI:10.1002/adhm.201300309
  115. H. Choi, M. Tanaka, T. Hiragun, M. Hide, K. Sugimoto, Non-tumor mast cells cultured in vitro on a honeycomb-like structured film prpliferate with multinucleateaed formation, Nanomedicine, 10, 313-319 (2014).
    DOI:10.1016/j.nano.2013.08.011
  116. J.O. Eniwumide, M.Tanaka, N. Nagai, Y. Morita, J.De Bruijn , S. Yamamoto, S. Onodera, E. Kondo, K. Yasuda, M. Shimomura. The Morphology and Functions of Articular Chondrocytes on a Honeycomb-Patterned Surface, BioMed Research International, 2014, 710354 (2014).
    DOI:10.1155/2014/710354

    2013
  117. M. Birch, M. Tanaka, G. Kirmizidis, S. Yamamoto, M. Shimomura, Microporous "Honeycomb" Films Support Enhanced Bone Formation in Vitro Tissue Engineering A, 19, 2087-2096, 2013.
    DOI:10.1089/ten.TEA.2012.0729
  118. T. Hoshiba, M. Tanaka, Breast cancer cell behaviors on staged tumorigenesis-mimicking matrices derived from tumor cells at various malignant stages, Biochemical and Biophysical Research Communications, 439, 291-296, 2013.
    DOI:10.1016/j.bbrc.2013.08.038
  119. M. Tanaka, T. Hayashi, S. Morita, The roles of water molecule at the biointerface of medical polymers, Polym. J., 45, 701-710, 2013. (Invited paper: SPSJ Asahi Kasei Award).
    DOI:10.1038/pj.2012.229

    2012
  120. T. Hayashi, Y. Tanaka, Y. Koide, M. Tanaka, M. Hara, Mechanism Underlying Bioinertness of Self-assembled Monolayers of Oligo(ethyleneglycol)-terminated Alkanethiols on Gold: Protein Adsorption, Platelet Adhesion, and Surface Forces, Physical Chemistry Chemical Physics, 14,10194-10206, 2012.
    DOI:10.1039/c2cp41236e     
  121. I. Javakhishvili, M. Tanaka, K. Ogura, K. Jankova, S. Hvilsted, Synthesis of graft copolymers based on poly(2-methoxyethyl acrylate) and investigation of the associated water structure, Macromol. Rapid Commun., 33, 319-325, 2012.
    DOI:10.1002/marc.201100698
  122. T. Hatakeyama, A. Kishi, M. Tanaka, Comparison of measurement techniques for the identification of bound water restrained by polymers, Thermochim Acta, 532, 159-163, 2012.
    DOI:10.1016/j.tca.2011.01.027

    2011
  123. M. Tanaka, Design of Novel 2D and 3D Bio-Interfaces using Self-Organization to Control Cell behavior, Nanotechnologies: Emerging Applications in Biomedicine, Biochimica et Biophysica Acta (BBA) - General Subjects, 1810, 251-258, 2011.
    DOI:10.1016/j.bbagen.2010.10.002
  124. T. Hirata, H. Matsuno, M. Tanaka, K. Tanaka, Surface Segregation of Poly(2-methoxyethyl acrylate) in a Mixture with Poly(methyl methacrylate), Physical Chemistry Chemical Physics, 13, 4928-4934, 2011.
    DOI:10.1039/c0cp02101f
  125. Y. Miwa, M. Tanaka, A. Mochizuki, Analyses of Water structures and dynamics of swollen blood compatible polymers, Koubunshi Ronbunshu, 68, 133-146, 2011.
    DOI:10.1295/koron.68.133

    2010
  126. M. Tanaka, A. Mochizuki, Clarification of the Blood Compatibility Mechanism by Controlling the Water Structure at the Blood–Poly(meth)acrylate Interface, J. Biomat. Sci. Polym. Ed., 21, 1849-1863, 2010.
    DOI:10.1163/092050610X517220
  127. T. Sato, M. Tanaka, S. Yamamoto, E. Ito, K. Shimizu, Y. Igarashi, M. Shimomura, J. Inokuchi, Effect of Honeycomb-Patterned Surface Topography on the Function of Mesenteric Adipocytes, J. Biomat. Sci. Polym. Ed., 21, 1947-1956, 2010.
    DOI:10.1163/092050610X500615
  128. S. Morita, M. Tanaka, K. Kitagawa, Y. Ozaki, Hydration structure of poly(2-methoxyethyl acrylate): comparison with a 2-methoxyethyl acetate model monomer, J. Biomat. Sci. Polym. Ed., 21, 1925-1935, 2010.
    DOI:10.1163/092050610x494613
  129. Y. Miwa, H. Ishida, M. Tanaka, A. Mochizuki, 2H-NMR and 13C-NMR Study of the Hydration Behavior of Poly(2-methoxyethyl acrylate), Poly(2-hydroxyethyl methacrylate) and Poly(tetrahydrofurfuryl acrylate) in Relation to Their Blood Compatibility as Biomaterials, J. Biomat. Sci. Polym. Ed., 21, 1911-1924, 2010.
    DOI:10.1163/092050610X489682
  130. T. Hatakayama, M. Tanaka, H. Hatakayama, Thermal Properties of Freezing Bound Water Restrained by Polysaccharides, J. Biomat. Sci. Polym. Ed., 21, 1865-1880, 2010.
    DOI:10.1163/092050610X486946
  131. A. Mochizuki, M. Kimura, A. Ina, Y. Tomono, M.Tanaka, Study on water structure and blood compatibility of poly(acryloylmorpholine-r-butyl methacrylate), J. Biomat. Sci. Polym. Ed., 21, 1895-1910, 2010.
    DOI:10.1163/092050610X489321
  132. T. Hatakayama, M. Tanaka, H. Hatakayama, Studies on bound water restrained by poly(2-methacryloyloxyethyl phosphorylcholine) (PMPC): Comparison of the polysaccharides-water systems, Acta Biomaterialia, 6, 2077-2082, 2010.
    DOI:10.1016/j.actbio.2009.12.018
  133. H. Ishihata, M. Tanaka, N. Iwama, M. Ara, M. Shimonishi, M. Nagamine, N. Murakami, S. Kanaya, E. Nemoto, H. Shimauchi, M. Shimomura, Proliferation of periodontal ligament cells on biodegradable honeycomb film scaffold with unified micropore organization, Journal of Biomechanical Science and Engineering, Special Issue on Micro and Nanobiotechnology for Cells, 5, 252-261, 2010.
    DOI:10.1299/jbse.5.252
  134. Y. Uraki, C. Matsumoto, T. Hirai, Y. Tamai, M. Enoki, H. Yabu, M. Tanaka, M. Shimomura, Mechanical effect of acetic acid lignin adsorption on honeycomb-patterned cellulosic films, Journal of Wood Chemistry and Technology, 30, 348-359, 2010.
    DOI:10.1080/02773811003746709

    2009
  135. M. Tanaka, M. Takebayashi, M. Shimomura, Fabrication of ordered arrays of biodegradable polymer pincushions using self-organized honeycomb-patterned film, Macromol .Symp., (Invited original paper). 279, 175-182, 2009.
    DOI:10.1002/masy.200950527
  136. M. Tanaka, H. Sato, Y. Sasaya, S. Horinouchi, J. Hotta, Y. Matsuo, K. Ijiro, K. Sasaki, M. Shimomura, Fabrication of Novel Biocompatible Surfaces by Two-Photon Absorption Technique Using Femtosecond Laser, Mol. Cryst. Liq. Cryst., 505, 219-230, 2009.
    DOI:10.1080/15421400902950121
  137. Y. Miwa, H.Ishida, H.Saitô, M. Tanaka, A. Mochizuki, Network structures and dynamics of dry and swollen poly(acrylate)s. Characterization of high- and low-frequency motions as revealed by suppressed or recovered intensities (SRI) analysis of 13C NMR, Polymer, 50, 6091- 6099, 2009.
    DOI:10.1016/j.polymer.2009.10.037
  138. A. Mochizuki, T. Hatakeyama, Y. Tomono, M. Tanaka, Water structure and blood compatibility of poly(tetrahydrofurfuryl acrylate). J. Biomat. Sci. Polym. Ed., 20, 591-603, 2009.
    DOI:10.1163/156856209x426411
  139. A. Mochizuki, A. Kishi, M. Tanaka, Comparative study on water structures in polyHEMA and polyMEA by XRD-DSC simultaneous measurement, J. Appl. Poly. Sci., 111, 476-481, 2009.
    DOI:10.1002/app.29127
  140. Y. M. Chen, J. P. Gong, M. Tanaka, K. Yasuda, S. Yamamoto, M. Shimomura, Y. Osada, Tuning of cell proliferation on tough gels by critical charge effect, J. Biomed. Mater. Res. A, 88A, 74-83, 2009.
    DOI:10.1002/jbm.a.31869
  141. S. Tada, C. Inaba, K. Mizukami, S. Fujishita, M. Gemmei-Ide, H. Kitano, A. Mochizuki, M. Tanaka, T. Matsunaga, Anti-Biofouling Properties of Polymers with a Carboxybetaine Moiety. Macromolecular Bioscience, 9(1), 63-70, 2009.
    DOI:10.1002/mabi.200800150

    2008
  142. M. Tanaka, K. Yoshizawa, A. Tsuruma, H. Sunami, S. Yamamoto, M. Shimomura, Formation of hydroxyapatite on a self-organized 3D honeycomb-patterned biodegradable polymer film, Colloids and Surfaces A: Physicochemical and Engineering Aspects, 313-314, 515-519, 2008.
    DOI:10.1016/j.colsurfa.2007.05.081
  143. K Arai, M. Tanaka, S. Yamamoto, M. Shimomura, Effect of pore size of honeycomb films on the morphology, adhesion and cytoskeletal organization of cardiac myocytes, Colloids and Surfaces A: Physicochemical and Engineering Aspects, 313-314, 530-535, 2008.
    DOI:10.1016/j.colsurfa.2007.04.128
  144. A. Tsuruma, M. Tanaka, S. Yamamoto, M. Shimomura, Control of neural stem cell differentiation on honeycomb films, Colloids and Surfaces A: Physicochemical and Engineering Aspects, 313-314, 536-540, 2008.
    DOI:10.1016/j.colsurfa.2007.05.079
  145. A. Tanabe, S. Morita, M. Tanaka, I. Noda, Y. Ozaki, Multivariate Curve Resolution Analysis on Multi-Component Water Sorption Process into a Poly(2-methoxyethyl acrylate) Film, Appl. Spec., 62, 46-50, 2008.
    DOI:10.1366/000370208783412555
  146. H. Kitano, K. Nagaoka, S. Tada, M. Gemmei-Ide, M. Tanaka, Structure of Water Incorporated in Amphoteric Polymer Thin Films as Revealed by FT-IR Spectroscopy, Macromolecular Bioscience, 8, 77-85, 2008.
    DOI:10.1002/mabi.200700082
  147. Y. Fukuhira, M. Ito, H. Kaneko, Y. Sumi, M. Tanaka, S. Yamamoto, M. Shimomura, Prevention of postoperative adhesions by honeycomb-patterned poly(lactide)film in rat experimental model, J. Biomed. Mater. Res. B, 86B, 353-359, 2008.
    DOI:10.1002/jbm.b.31026
  148. A. Nogami, E. Tominaga, Y. Sawa, T. Murata, Y. Kudo, M.Tanaka, M.Shimomura, Development of the honeycomb film filter for individual aerosol particle analysis, Earozoru Kenkyu, 23(2), 127-133, 2008.
    DOI:10.11203/jar.23.127
  149. S. Tsukiyama, M. Matsushita, M. Tanaka, H. Tamura, S. Todo, S. Yamamoto, M. Shimomura, Enhanced cell survival and yield of rat small hepatocytes by honeycomb-patterned films, Jp. J. Appl. Phys., Vol. 47, No. 2, 1429-1434, 2008.
    DOI:10.1143/JJAP.47.1429
  150. Y. Fukuhira, H. Kaneko, M. Yamaga, M. Tanaka, S. Yamamoto, M. Shimomura, Effect of honeycomb-patterned structure on chondrocyte behavior in vitro, Colloids and Surfaces A: Physicochemical and Engineering Aspects, 313-314, 520-525, 2008.
    DOI:10.1016/j.colsurfa.2007.05.047

    2007
  151. M. Tanaka, A. Takayama, E. Ito, H. Sunami, S. Yamamoto M. Shimomura, Effect of pore size of self-organized honeycomb-patterned polymer films on spreading, focal adhesion, proliferation, and function of endothelial cells, J. Nanosci. Nanotech., 7, 763-772, 2007.
    DOI:10.1166/jnn.2007.514
  152. S. Yamamoto, M. Tanaka, E. Ito, Y. Morita , H. Sunami, K. Ijiro, M. Shimomura, The influence of pore size of a honeycomb film on early spreading process of endtherial cells, J. Surf. Sci. Soc. Jap., 28(8), 433-439, 2007.
    DOI:10.1380/jsssj.28.433
  153. T. Okajima, M. Tanaka, S. Tsukiyama, T. Kadowaki, S. Yamamoto, M. Shimomura, H. Tokumoto, Stress Relaxation and Fluctuation of Living Cells Measured by Atomic Force Microscopy, Jp. J. Appl. Phys., 46 (8B), 5552-5555, 2007.
    DOI:10.1143/JJAP.46.5552
  154. S. Yamamoto, M. Tanaka, H. Sunami, S. Yamashita, Y. Morita, M. Shimomura, Effects of honeycomb-patterned surface topography on the adhesion and signal transduction of porcine aortic endothelial cells, Langmuir, 23, 8114-8120, 2007.
    DOI:10.1021/la700332610.1021/la7003326
  155. J.R. McMillan, M. Akiyama, M. Tanaka, S. Yamamoto, M. Goto, R. Abe, D. Sawamura, M. Shimomura, H. Shimizu, Small-diameter porous poly (epsilon-caprolactone) films enhance adhesion and growth of human cultured epidermal keratinocyte and dermal fibroblast cells., Tissue Engineering, 13, 789-798, 2007.
    DOI:10.1089/ten.2006.0321
  156. Y. M. Chen, M. Tanaka, JP Gong, K Yasuda, S. Yamamoto, M. Shimomura, Y. Osada, Platelet adhesion to human umbilical vein endothelial cells cultured on anionic hydrogel scaffolds, Biomaterials, 28, 1752-1760, 2007.
    DOI:10.1016/j.biomaterials.2006.12.005
  157. T. Okajima, M. Tanaka, S. Tsukiyama, T. Kadowaki, S. Yamamoto, M. Shimomura, H. Tokumoto, Stress relaxation of HepG2 cells measured by atomic force microscopy, Nanotechnology, 18, 084010-4, 2007.
    DOI:10.1088/0957-4484/18/8/084010
  158. S. Morita, M. Tanaka, Y. Ozaki, Time-Resolved In-Situ ATR-IR Observations of Water Sorption Process into a Poly(2-methoxyethyl acrylate) (PMEA) Film, Langmuir, 23, 3750-3761, 2007.
    DOI:10.1021/la0625998
  159. T. Hayashi, M. Tanaka, S. Yamamoto, M. Shimomura, M. Hara, Direct observation of biocompatibility of  PMEA(poly(2-methoxyethyl acrylate)) using Atomic Force Microscopy, Biointerphases, 2(4), 1-9 , 2007.
    DOI:10.1116/1.2794712
  160. S. Morita, M. Tanaka, I. Noda, Y. Ozaki, Phase Angle Description of Perturbation Correlation Analysis and Its Application to Time-Resolved IR Spectra, Appl. Spec.,61(8), 867-872, 2007.
    DOI:10.1366/000370207781540051
  161. E. Hirota, M. Tanaka, A. Mochizuki, Blood Compatibility and Water Structure-Comparative Study between 2-Methoxyethylacrylate- and 2-Methoxyethylmethacrylate-based random copolymers, J. Biomed. Mater. Res. 81A, 710-719, 2007.
    DOI:10.1002/jbm.a.31113
  162. Y. Uraki, J. Nemoto, H. Otsuka, Y. Tamai, J. Sugiyama, T. Kishimoto, M. Ubukata, H. Yabu, M. Tanaka, M. Shimomura, Honeycomb-Like Architecture Produced by Living Bacteria, Gluconacetobacter xylinus, Carbohydrate Polymers, 69, 1-6, 2007.
    DOI:10.1016/j.carbpol.2006.08.021
  163. T. Hatakeyma, H. Kasuga, M. Tanaka, H. Hatakeyama, Cold crystallization of poly(ethylene glcyol)-water systems, Thermochim Acta, 465, 59-66, 2007.
    DOI:10.1016/j.tca.2007.09.005

    2006
  164. S. Yamamoto, M. Tanaka, H. Sunami, S. Yamashita, Y. Morita, M. Shimomura, Relationship between adsorbed fibronectin and cell adhesion on a honeycomb-patterned film, Surf. Sci., 600, 3785-3791, 2006.
    DOI:10.1016/j.susc.2006.01.085
  165. M. Tanaka, K. Nishikawa, H. Okubo, H. Kamachi, T. Kawai, M. Matsushita, S. Todo, M. Shimomura, Control of hepatocyte adhesion and function on self-organized honeycomb-patterned polymer film, Colloids and Surfaces A: Physicochemical and Engineering Aspects, 284-285, 464-469, 2006.
    DOI:10.1016/j.colsurfa.2005.11.098
  166. A. Tsuruma, M. Tanaka, S. Yamamoto, N. Fukushima, H. Yabu, M. Shimomura, Topographical control of neurites extension on stripe-patterned polymer films, Colloids and Surfaces A: Physicochemical and Engineering Aspects, 284-285, 470-474, 2006.
    DOI:10.1016/j.colsurfa.2005.11.100
  167. S. Yamamoto, M. Tanaka, H. Sunami, S. Yamashita, Y. Morita, M. Shimomura, Relationship between Adsorbed Fibronectin and Cell Adhesion on a Honeycomb-patterned Film, J. Surf. Sci. Soc. Jap., 27(10), 2006.
    DOI:10.1380/jsssj.27.502
  168. H. Sunami, E. Ito, M. Tanaka, S.Yamamoto, M. Shimomura, Effect of honeycomb film on protein adsorption, cell adhesion and proliferation. Colloids and Surfaces A: Physicochemical and Engineering Aspects, 284-285, 548-551, 2006.
    DOI:10.1016/j.colsurfa.2005.11.041
  169. Y. Fukuhira, E. Kitazono, T. Hayashi, H. Kaneko, M. Tanaka, M. Shimomura, Y. Sumi, Biodegradable honeycomb-patterned film composed of poly(lactic acid) and dioleoylphosphatidylethanolamine, Biomaterials, 27, 1797-1802, 2006.
    DOI:10.1016/j.biomaterials.2005.10.019
  170. E. Hirota, K. Ute, M. Uehara, T. Kitayama, M. Tanaka, A. Mochizuki, -Study of Blood Compatibility with Poly(2-Methoxyethylacrylate) - Relationship between Surface Structure, Water Structure and Platelet Compatibility in 2-Methoxyethylacrylate/2-Hydroxyethylmethacrylate Diblock Copolymer, J. Biomed. Mater. Res., 76A, 540-550, 2006.
    DOI:10.1002/jbm.a.30563
  171. M. Shimomura, A. Tsuruma, M. Tanaka, H. Sunami, S. Yamamoto, Biomedical application of patterned polymer films prepared by self-organization, J. Surf. Sci. Soc. Jap., 27, 170-175, 2006.
    DOI:10.1380/jsssj.27.170

    2005
  172. A. Tsuruma, M. Tanaka, N. Fukushima, M. Shimomura, Morphological changes in neurons by self-organized patterned films, e-J. Surf. Sci. Nanotech., 3, 159-164, 2005.
    DOI:10.1380/ejssnt.2005.159
  173. H. Kitano, T. Mori, Y. Takeuchi, S. Tada, M. Gemmei-ide, Y. Yokoyama, M. Tanaka, Structure of Water Incorporated in Sulfobetaine Polymer Films as Studied by ATR-FTIR, Macromol. Biosci., 5(4), 314-321, 2005.
    DOI:10.1002/mabi.200400212
  174. J. Nemoto, Y. Uraki, T. Kishimoto, Y. Sano, R. Funada, N. Obata, H. Yabu, M. Tanaka, M. Shimomura, Production of mesoscopically patterned cellulose film, Bioresource Technol, 96(17), 1955-1958, 2005.
    DOI:10.1016/j.biortech.2005.01.034
  175. H. Kitano, S. Tada, T. Mori, K. Takaha, M. Gemmei-Ide, M. Tanaka, M. Fukuda, Y. Yokoyama, Correlation between the Structure of Water in the Vicinity of Carboxybetaine Polymers and Their Blood-Compatibility, Langmuir, 21, 11932-11940, 2005.
    DOI:10.1021/la0515571
  176. H. Yabu, M. Takebayashi, M. Tanaka, M. Shimomura, Superhydrophobic and Lipophobic Properties of Self-Organized Honeycomb and Pincushion Structures, Langmuir, 21(8), 3235-3237, 2005.
    DOI:10.1021/la050013w

    2004年以前
  177. M. Tanaka, A. Mochizuki, Effect of water structure on blood compatibility-Thermal analysis of water in poly(meth)acrylate-, J. Biomed. Mater. Res., 68A(3), 684-695, 2004.
    DOI:10.1002/jbm.a.20088
  178. M. Tanaka, Design of Novel BioInterfaces (I) -Blood compatibility of poly(2-methoxyethyl acrylate)-, Bio-Med. Mater. Eng., 14, 427-438, 2004.
    [HTML]
  179. M. Tanaka, M. Takebayashi, M. Miyama, J. Nishida, M. Shimomura, Design of Novel BioInterfaces (II) -Fabrication of self-organized porous polymer film with highly uniform pores-, Bio-Med. Mater. Eng., 14, 439-446, 2004.
    [HTML]
  180. G. Li, S. Morita, S. Ye, M. Tanaka, M. Osawa, Bisphenol QCM and IRRAS Characterization of Bisphenol A Absorption in the Poly(acrylate) Thin Films, Anal. Chem.76, 788-795, 2004.
    DOI:10.1021/ac0348874
  181. A. Tsuruma, M. Tanaka, N. Fukushima, M. Shimomura, Control of neurites extension by self-organized patterned polymer films, Koubunshi Ronbunshuu, 61(12), 628-633, 2004.
    [PDF]
  182.  M. Ide, T. Mori, K. Ichikawa, H. Kitano, M.Tanaka, A. Mochizuki, H. Oshiyama, W. Mizuno, Structure of Water Sorbed into Poly(MEA-co-HEMA) Films As Examined by ATR-IR Spectroscopy, Langmuir, 19, 429-435, 2003.
    DOI:10.1021/la020617p
  183. M. Tanaka, Blood Compatibility of Poly(2-methoxyethyl acrylate) - Design of Novel Biointerfaces, Koubunshi Ronbunshuu, 60(8), 415-427, 2003.
    DOI:10.1295/koron.60.415
  184. S. Ye, S. Morita, G. Li, H. Noda, M. Tanaka, K. Uosaki, M. Osawa, Interfacial Molecular Structure Changes in Poly(2-methoxyethyl acrylate) Thin Films Induced by Absorption of Bisphenol A. An Infrared and Sum Frequency Generation (SFG) Study, Macromolecules, 36, 5694-5703, 2003.
    DOI:10.1021/ma026007d
  185. H. Yabu, M. Tanaka, K. Ijiro, M. Shimomura, Preparation of honeycomb patterned polyimide films by self-organization, Langmuir, 19, 6297-6300, 2003.
    DOI:10.1021/la034454w
  186. M. Tanaka, A. Mochizuki, N. Ishii, T. Motomura, T. Hatakeyama, Study of Blood Compatibility With poly(2-methoxyethyl Acrylate). Relationship Between Water Structure and Platelet Compatibility in poly(2-methoxyethylacrylate-co- 2-hydroxyethylmethacrylate), Biomacromolecules, 3, 36-41, 2002.
    DOI:10.1021/bm010072y
  187. M. Tanaka, A. Mochizuki, T. Shiroya, T. Motomura, K. Shimura, M. Onishi, Y. Okahata, Study on kinetics of early stage protein adsorption on poly(2-methoxyethylacrylate) (PMEA) surface. Colloids and Surfaces A: Physicochemical and Engineering Aspects, 203, 195-204, 2002.
    DOI:10.1016/S0927-7757(01)01100-1
  188. K. Sato, M. Tanaka, K. Hasebe, M. Takebayashi, K. Nishikawa, T. Kawai, M. Matsushita, S. Todo, M. Shimomura, Preparation of the honeycomb patterned porous film of biodegradable polymer for tissue engineering scaffolds, Inter. J. Nanosci., 1(5,6), 689-693, 2002.
    DOI:10.1142/9789812796714_0055
  189. M.Tanaka, A. Mochizuki, T. Motomura, K. Shimura, M. Onishi, Y. Okahata. In Situ Studies on Protein Adsorption onto a Poly(2-methoxyethyl acrylate) Surface by a Quartz Crystal Microbalance. Colloids and Surfaces A: Physicochemical and Engineering Aspects, 193, 145-152, 2001.
    DOI:10.1016/S0927-7757(01)00682-3
  190. H. Kitano, K. Ichikawa, M. Fukuda, A. Mochizuki, M. Tanaka, The Structure of Water Sorbed to Polymethylmethacrylate Film As Examined by FT-IR Spectroscopy, J. Colloid Surface Sci., 242, 133-140, 2001.
    DOI:10.1006/jcis.2001.7785
  191. K. Ichikawa, T. Mori, H. Kitano, M. Fukuda, A. Mochizuki, M. Tanaka, A FT-IR Study on the Sorption of Water to Various Kinds of Polymer Thin Films, J. Polym. Sci., B Polym. Phys. 39, 2175-2182, 2001.
    DOI:10.1002/polb.1191
  192. L. Schiel, S. Burns, A. Nogawa, R. Rice, T. Anzai, M. Tanaka, X-Coating : A New Biopassive Polymer Coating, Canadian Perfusion Canadienne, 11(2), 8-17, 2001.
    [PDF]
  193. M. Tanaka, T. Motomura, N. Ishii, K. Shimura, M. Onishi, A. Mochizuki, T. Hatakeyama, Cold crystallization of water in hydrated Poly(2-methoxyethyl acrylate) (PMEA), Polymer International, 49, 1709-1713, 2000.
    DOI:10.1002/1097-0126(200012)49:12<1709::AID-PI601>3.0.CO;2-L
  194. M. Tanaka, T. Motomura, M. Kawada, T. Anzai, Y. Kasori, T. Shiroya, K. Shimura, M. Onishi, A. Mochizuki, Y. Okahata, A new blood-compatible surface prepared by Poly(2-methoxyethyl acrylate) (PMEA) coating -Protein adsorption on PMEA surface-, Jpn. J.Art. Org, 29, 209-216, 2000.
    DOI:10.11392/jsao1972.29.209
  195. M. Tanaka, T. Motomura, M. Kawada, T. Anzai, Y. Kasori, T. Shiroya, K. Shimura, M. Onishi, A. Mochizuki, Blood compatible aspects of Poly(2-methoxyethylacrylate) (PMEA) -Relationship between protein adsorption and platelet adhesion on PMEA surface-, Biomaterials, 21, 1471-1481, 2000.
    DOI:10.1016/S0142-9612(00)00031-4
  196.  M.Shimomura, F.Nakamura, K.Ijiro, H.Taketsuna, M.Tanaka, H.Nakamura, K.Hasebe, Two-dimrnsional DNA-mimetic monolayer organization at the air-water interface, J. Am. Chem. Soc., 119, 2341-2342, 1997.
    DOI:10.1021/ja962847u
  197. K.Ijiro, M.Shimomura, M.Tanaka, H.Nakamura, K.Hasebe, DNA monolayers complexed with amphiphilic intercalator at the air water interface, Thin Solid Films, 284-285, 780-783, 1996.
    DOI:10.1016/S0040-6090(95)08445-2
  198. M.Shimomura, F.Nakamura, K.Ijiro, H.Taketsuna, M.Tanaka, H.Nakamura, K.Hasebe, Chiral crystal formation of octadecylcytosine monolayer by complementary base-paring, Thin Solid Films, 284-285691-693, 1996.
    DOI:10.1016/S0040-6090(95)08422-3

Challenges for Biomaterials Design and Applications to Accelerating Healthcare Innovation