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Original articles, Books and Critical reviews

Original articles


  1. T. Sonoda, S. Kobayashi, K. Herai, M. Tanaka, Side chain spacing control of derivatives of poly(2-methoxyethyl acrylate): impact on hydration states and antithrombogenicity, Macromolecules, 53, 8570-8580 (2020).
    DOI: 10.1021/acs.macromol.0c01144
  2. S. Nishimura, T. Ueda, S. Kobayashi, M. Tanaka, Silsesquioxane/Poly(2-methoxyethyl acrylate) Hybrid with Both Antithrombotic and Endothelial Cell Adhesive Properties, ACS Applied Polymer Materials, In press.
    DOI: 10.1021/acsapm.0c00776
  3. Y. Toyokawa, S. Kobayashi, H. Tsuchiya, T. Shibuya, M. Aoki, J. Sumiya, S. Ooyama, T. Ishizawa, N. Makino, Y. Ueno, M. Tanaka, A fully covered self-expandable metallic stent coated with poly (2-methoxyethyl acrylate) and its derivative: In vitro evaluation of early-stage biliary sludge formation inhibition, Materials Science & Engineering C, In press.
    DOI: 1016/j.msec.2020.111386
  4. A.T. Kuo, T. Sonoda, S. Urata, R. Koguchi, S. Kobayashi, M. Tanaka, Elucidating the Feature of Intermediate Water in Hydrated Poly(ω-methoxyalkyl acrylate)s by Molecular Dynamics Simulation and Differential Scanning Calorimetry Measurement, ACS Biomater. Sci. Eng., 6(7), 3915-3924 (2020).
    DOI: 10.1021/acsbiomaterials.0c00746
  5. R. Koguchi, K. Jankova, Y. Hayasaka, D. Kobayashi, Y. Amino, T. Miyajima, S. Kobayashi, D. Murakami, K. Yamamoto, M. Tanaka, Understanding the effect of hydration on the bio-inert properties of HEMA copolymers with small amounts of amino- or/and fluorine-containing monomers, ACS Biomater. Sci. Eng., 6, 2855-2866 (2020).
    DOI: 10.1021/acsbiomaterials.0c00230
  6. M-Y. Tsai, F. Aratsu, S. Sekida, S. Kobayashi, M. Tanaka, Blood-compatible poly(2-methoxyethyl acrylate) induces blebbing-like phenomenon and promotes viability of tumor cells in serum-free medium, ACS Applied Bio Materials, 31858-1864 (2020).
    DOI: 10.1021/acsabm.9b00885
  7. D. Murakami, Y. Segami, T. Ueda, M. Tanaka, Control of interfacial structures and anti-platelet adhesion property of blood-compatible random copolymers, J. Biomater. Sci. Polym. Ed., 31, 207-218 (2020).
    DOI: 10.1080/09205063.2019.1680930
  8. M. Watanabe, Y. Tanaka, D. Murakami, M. Tanaka, M. Kawai, T. Mitsumata, Optimal plasticizer content for magnetic elastomers used for cell culture, Chemistry Letters, 49, 280-283 (2020).
    DOI: 10.1246/cl.190929


  9. M. Tanaka, S. Kobayashi, D. Murakami, F. Aratsu, A. Kashiwazaki, T. Hoshiba, K. Fukushima, Design of Polymeric Biomaterials: The “Intermediate Water Concept”, Bull. Chem. Soc. Jpn., 92, 2043-2057 (2019).
    DOI: 10.1246/bcsj.20190274
  10. K. Jankova, I. Javakhishvili, S. Kobayashi, R. Koguchi, D. Murakami, T. Sonoda, M. Tanaka, Hydration states and blood compatibility of Hydrogen-bonded supramolecular poly(2-methoxyethyl acrylate), ACS Appl. Bio Mater., 2, 4154-4161 (2019).
    DOI: 10.1021/acsabm.9b00363
  11. T. Araki, F. Yoshida, T. Uemura, Y. Noda, S. Yoshimoto, T. Kaiju, T. Suzuki, H. Hamanaka, K. Baba, H. Hayakawa, T. Yabumoto, H. Mochizuki, S. Kobayashi, M. Tanaka, M. Hirata, T. Sekitani, Long-term implantable, flexible, and transparent neural interface based on Ag/Au core-shell nanowires, Adv. Healthcare Mater., 8, 1900130 (2019).
    DOI: 10.1002/adhm.201900130
  12. R. Koguchi, K. Jankova, N. Tanabe, Y. Amino, Y. Hayasaka, D. Kabayashi, T. Miyajima, K. Yamamoto, M. Tanaka, Controlling the hydration structure with small amount of fluorine to produce blood compatible fluorinated poly(2-methoxyethyl acrylate), Biomacromolecules, 20, 2265-2275 (2019).
    DOI: 10.1021/acs.biomac.9b00201
  13. A.-T. Kuo, S. Urata, R. Koguchi, K. Yamamoto, M. Tanaka, Analyses of Equilibrium Water Content and Blood Compatibility for Poly(2-methoxyethyl acrylate) by Molecular Dynamics Simulation, Polymer, 170, 76-84 (2019).
    DOI: 10.1016/j.polymer.2019.03.001
  14. M. Okada, E. Hara, D. Kobayashi, S. Kai, K. Ogura, M. Tanaka, T. Matsumoto, Intermediate water on calcium phosphate minerals: its origin and role in crystal growth, ACS Applied Bio Materials, 2, 981-986 (2019).
    DOI: 10.1021/acsabm.9b00014
  15. D. Murakami, N. Mawatari, T. Sonoda, A. Kashiwazaki, M. Tanaka, Effect of Molecular Weight of Poly(2-methoxyethylacrylate) on Interfacial Structure and Blood Compatibility. Langmuir, 35, 2808-2813 (2019).
    DOI: 10.1021/acs.langmuir.8b02971


  16. W. Lee, S. Kobayashi, M. Nagase, Y. Jimbo, I. Saito, Y. Inoue, T. Yambe, M. Sekino, G. G Malliaras, T. Yokota, M. Tanaka, T. Someya, A Nonthrombogenic, Stretchable, Active Multielectrode Array using Organic Electrochemical Transistors, Science Advances, 4(10), eaau2426 (2018).
    DOI: 10.1126/sciadv.aau2426
  17. T.Ueda, D. Murakami, M. Tanaka. Analysis of interaction between interfacial structure and fibrinogen at blood-compatible polymer/water interface. Frontiers in Chemistry, Polymer Surface Chemistry: Biomolecular Engineering and Biointerfaces, 6, 542 (2018).
    DOI: 10.3389/fchem.2018.00542
  18. F. Khan, F. Aratsu, S. Kobayashi, M. Tanaka, A Simple Strategy for Robust Hydrogel Preparation and Characterisation Derived from Chitosan and Amino Functional Monomers for Biomedical Applications, Journal of Materials Chemistry B, 6, 5115-5129 (2018).
    DOI: 10.1039/C8TB00865E
  19. D. Murakami, Y. Kitahara, S. Kobayashi, M. Tanaka, Thermosensitive Polymer Biocompatibility based on Interfacial Structure at BiointerfaceACS Biomaterials Science & Engineering, 4, 1591-1597 (2018). 
  20. M. Mabrouk, H. H.  Beherei, S. ElShebiney, M. Tanaka, Newly developed controlled release subcutaneous formulation for tramadol hydrochloride, Saudi Pharmaceutical Journal, 26, 585-592 (2018).
    DOI: 10.1016/j.jsps.2018.01.014
  21. F. Khan, M. Tanaka, Designing Smart Biomaterials for Tissue Engineering, International Journal of Molecular Sciences, 19(1), 17 (2018). 
  22. T. Hoshiba, K. Sato, N. Kawazoe, G. CHEN, M. Tanaka, Chondrocyte shapes and detachment on a thermo-responsive poly (2-methoxyethyl acrylate) analog for the development of new chondrocytes subculture substrate, Chemistry Letters, 47(1), 107-109 (2018).


  23. S. Kobayashi, M. Wakui, Y. Iwata, M. Tanaka, Poly(ω-methoxyalkyl acrylate)s: A nonthrombogenic polymer family with tunable protein adsorption, Biomacromolecules, 18 (12), 4214-4223 (2017).
  24. K. Fukushima, Y. Inoue, Y. Haga, T. Ota, K. Honda, C. Sato, M. Tanaka, Monoether-tagged Biodegradable Polycarbonate Preventing Platelet Adhesion and Demonstrating Adhesion of Vascular Cells: A Promising Material for Resorbable Vascular Grafts and Stents, Biomacromolecules18 (11), 3834–3843 (2017).
    DOI: 10.1021/acs.biomac.7b01210
  25. T. Hoshiba, H. Maruyama, K. Sato, C. Endo, N. Kawazoe, G. Chen, M. Tanaka, Maintenance of Cartilaginous Gene Expression of Serially Subcultured Chondrocytes on Poly(2-Methoxyethyl Acrylate) Analogous Polymers, Macromol. Biosci.,17,170297(2017) .
    DOI: 10.1002/mabi.201700297
  26. K. Fukushima, K. Honda, Y. inoue, M. Tanaka, Synthesis of Antithrombotic Poly(carbonate-urethane)s through a Sequential Process of Ring-Opening Polymerization and Polyaddition Facilitated by Organocatalysts, Eur. Polym. J., Vol. 95,  728-736 (2017).
    DOI: 10.1016/j.eurpolymj.2017.07.001
  27. K. Sato, S. Kobayashi, A. Sekishita, M. Wakui, M. Tanaka, Synthesis and Thrombogenicity Evaluation of Poly(3-methoxypropionic acid vinyl ester): a candidate for blood compatible polymer, Biomacromolecules, 18, 1609-1616 (2017).
    DOI: 10.1021/acs.biomac.7b00221
  28. T. Hoshiba, A.Yoshihiro, M. Tanaka, Evaluation of initial cell adhesion on poly (2-methoxyethyl acrylate) (PMEA) analogous polymers, J. Biomat. Sci. Polym. Ed., 28, 986-999 (2017).
    DOI: 10.1080/09205063.2017.1312738
  29. T. Sekine, S. Asatyas, C. Sato, S. Morita, M. Tanaka, T. Hayashi, Surface force and vibrational spectroscopic analyses of interfacial water molecules in the vicinity of methoxy-tri(ethylene glycol)-terminated monolayers: mechanisms underlying the effect of lateral packing density on bioinertness, J. Biomat. Sci. Polym. Ed., 28, 1231-1243 (2017).
    DOI: 10.1159/000451043
  30. Y. Inoue,  T. Yokota, T. Sekitani, A. Kaneko, T. Woo, S. Kobayashi, T.Shibuya, M. Tanaka, H. Koshukegawa, I. Saito, T. Isoyama, Y. Abe, T.Yambe, T. Someya, M. Sekino, Antithrombotic Protein Filter Composed of Hybrid Tissue-Fabric Material has a Long Lifetime, Annals of Biomedical Engineering, 45(5), 1352-1364 (2017).
    DOI: 10.1007/s10439-016-1781-5
  31. T. Hirata, H. Matsuno, D. Kawaguchi, M. Inutsuka, T. Hirai, M. Tanaka, K. Tanaka, Dynamics of a bioinert polymer in hydrated states by dielectric relaxation spectroscopy, Physical Chemistry Chemical Physics, 19,1389-1394 (2017).
    DOI: 10.1039/c6cp07322k


  32. T. Hoshiba, E. Nemoto, K. Sato, H. Maruyama, C. Endo, M. Tanaka, Promotion of adipogenesis of 3T3-L1 cells on protein adsorption-suppressing poly (2-methoxyethyl acrylate) analogous polymers, Biomacromolecules, 17,3808-3815 (2016).
  33. D. Murakami, S. Kobayashi, M. Tanaka, Interfacial Structures and Fibrinogen Adsorption at Blood-Compatible Polymer/Water Interfaces, ACS Biomater. Sci. Eng., 2, 2122–2126 (2016).
  34. K. Osawa, S. Kobayashi, M. Tanaka, Synthesis of Sequence-Specific Polymers with Amide Side-chains via Regio-/stereoselective Ring-opening Metathesis Polymerization of 3-Substituted cis-Cycloocte, Macromolecules, 49, 8154-8161 (2016).
  35. T. Hoshiba, M. Tanaka, Integrin-independent cell adhesion substrates:Possibility of applications for mechanobiology research, Special Issue:Mechanobiology, Analytical Sciences, 32,1151-1158 (2016).
  36. T. Hoshiba, T. Orui, C. Endo, K. Sato, A. Yoshihiro, Y. Minagawa, M.Tanaka, Adhesion-Based Simple Capture and Recovery of Circulating Tumor Cells Using a Blood-Compatible and Thermo-Responsive Polymer-Coated Substrate, RSC Advances, 6, 89103-89112 (2016).
  37. A. Basterretxea, Y. Haga, A. Sanchez-Sanchez, M. Isik, L. Irusta, M. Tanaka, K. Fukushima, H. Sardon, Biocompatibility and hemocompatibility evaluation of polyether urethanes synthesized using DBU organocatalyst, Eropean Polymer Journal, 84, 750-758 (2016).
  38. T. Hoshiba, M.Tanaka, Decellularized matrices as in vitro models of extracellular matrix in tumor tissues at different malignant levels:Mechanism of 5-fluorouracil resistance in colorectal tumor cells, BBA - Molecular Cell Research, 1863,2749-2757 (2016).
  39. K. Kono, H. Hiruma, S. Kobayashi, Y. Sato,  M.Tanaka, R. Sawada, S. Niimi, In vitro endothelialization test of biomaterials using immortalized endothelial cells, PLoS One, 11(6), e01582898 (2016).
  40. S. Kobayashi, K. Fukuda, M. Kataoka, M. Tanaka, Regioselective Ring-Opening Metathesis Polymerization of 3-Substituted Cyclooctenes with Ether Side-Chains, Macromolecules, 49(7), 2493-2501 (2016).
  41. C. Sato, M. Aoki, M. Tanaka, Blood-compatible poly(2-methoxyethyl acrylate) for the adhesion and proliferation of endothelial and smooth muscle cells, Colloids and Surfaces B: Biointerfaces,145, 586-596 (2016).
  42. T. Hoshiba, M. Nikaido, S.Yagi, I. Konno, A. Yoshihiro, M. Tanaka, Blood-compatible poly (2-methoxyethyl acrylate) for the adhesion and proliferation of lung cancer cells toward the isolation and analysis of circulating tumor cells, Journal of Bioactive and Compatible Polymers, 31, 361-372 (2016).
  43. H. Choi, M. Tanaka, K. Sugimoto, Difference in cell proliferation and spontaneous mediator release between two mast cell lines, NCL-2 and RBL-2H3 on honeycomb-like structured film, Journal of Nanotechnology: Nanomedicine & Nanobiotechnology, 3(009) (2016).
  44.  T. Hoshiba, G. Chen, C. Endo, H. Maruyama, M. Wakui, E. Nemoto, N. Kawazoe, M. Tanaka. Decellularized extracellular matrix (ECM) as an in vitro model to study the comprehensive roles of the ECM in stem cell differentiation. Stem Cells Int., 2016, 6397820 (2016).


  45. T. Hoshiba, T. Otaki, E. Nemoto, H. Maruyama, M. Tanaka. Blood compatible polymer for hepatocyte culture with high hepatocyte-specific functions toward bioartificial liver development. ACS Appl. Mater. Interfaces 7, 18096-18103 (2015).
  46. T. Hirata, H. Matsuno, D. Kawaguchi, N. Yamada, M. Tanaka, K. Tanaka, Construction of a blood-compatible interface based on surface segregation in a polymer blend, Polymer, 78, 219-224 (2015).
  47. F. Khan, M. Tanaka, S.R. Ahmad, Fabrication of polymeric biomaterials: a strategy for tissue engineering and medical devices, Journal of Materials Chemistry B, 3, 8224-8249 (2015).
  48. T. Hoshiba, E. Nemoto, K. Sato, T. Orui, T. Otaki, A. Yoshihiro, M. Tanaka. Regulation of the contribution of integrin to cell attachment on poly(2-methoxyethyl acrylate) (PMEA) analogous polymers for attachment-based cell enrichment. PLoS One,10, e0136066 (2015).
  49. T. Sekine, Y. Tanaka, C. Sato, M. Tanaka, T. Hayashi, Evaluation of factors to determine platelet compatibility by using self-assembled monolayers with a chemical gradient, Langmuir, 31,7100-7105 (2015).
  50. K. Sato, S. Kobayashi, M. Kusakari, S. Watahiki, M. Oikawa, T. Hoshiba,  M. Tanaka, The relationship between water structure and blood compatibility in poly(2-methoxyethyl acrylate) (PMEA) analogues, Macromol. Biosci., 15, 1296-1303 (2015).
  51.  T. Hirata, H. Matsuno, D. Kawaguchi, N. Yamada, M. Tanaka, K. Tanaka, Effect of interfacial structure on bioinert property of poly(2-methoxyethyl acrylate)/ poly(methyl methacrylate) blend films in water, Phys. Chem. Chem. Phys., 17,17399-17405 (2015).
  52. K. Fukushima, M. Tsai, T. Ota, Y. Haga, K. Matsuzaki, Y. Inoue, M. Tanaka, Evaluation of the hemocompatibility of hydrated biodegradable aliphatic carbonyl polymers with a subtle difference in the backbone structure based on the intermediate water concept and surface hydration, Polym. J., 47, 469-473 (2015). 
  53. T. Hirata, H. Matsuno, D. Kawaguchi, T. Hirai, N. Yamada, M. Tanaka, K. Tanaka, Effect of Local Chain dynamics on a Bio-inert Interface, Langmuir, 31, 3661-3667 (2015).
  54. M. Tanaka, K. Sato, E. Kitakami, S. Kobayashi, T. Hoshiba, K. Fukushima, Design of biocompatible and biodegradable polymers based on the intermediate water concept, Polymer Journal, 47, 114-121 (2015). Invited paper: Special Issue on Fusion Materials, Most Accessed Papers(September - December 2015)
  55. T. Hoshiba, M. Tanaka, Optimization of the tissue source, malignancy, and initial substrate of tumor cell-derived matrices to increase cancer cell chemoresistance against 5-fluorouracil. Biochem. Biophys.Res. Commun., 457, 353-357 (2015).


  56. S. Morita, M. Tanaka, Effect of Sodium Chloride on Hydration Structures of PMEA and P(MPC-r-BMA), Langmuir, 30,10698-10703 (2014).
  57. K. Sugimoto, H. Choi, M. Tanaka, Honeycomb-like structured film regulates mediator release from non-tumor mast cells,  European Journal of Inflammation, 12, 515-520 (2014).
  58. E. Kitakami, M. Aoki, C. Sato, H. Ishihata, M. Tanaka, Adhesion and proliferation of human periodontal ligament cells on poly(2-methoxyethyl acrylate), BioMed Resarch International, 2014, 102648 (2014).
  59. T. Hoshiba, M. Nikaido, M. Tanaka, Characterization of the Attachment Mechanisms of Tissue-Derived Cell Lines to Blood-Compatible Polymers, Adv. Healthcare Mater., 3, 775-784 (2014).
  60. H. Choi, M. Tanaka, T. Hiragun, M. Hide, K. Sugimoto, Non-tumor mast cells cultured in vitro on a honeycomb-like structured film prpliferate with multinucleateaed formation, Nanomedicine, 10, 313-319 (2014).
  61. J.O. Eniwumide, M.Tanaka, N. Nagai, Y. Morita, J.De Bruijn , S. Yamamoto, S. Onodera, E. Kondo, K. Yasuda, M. Shimomura. The Morphology and Functions of Articular Chondrocytes on a Honeycomb-Patterned Surface, BioMed Research International, 2014, 710354 (2014).


  62. M. Birch, M. Tanaka, G. Kirmizidis, S. Yamamoto, M. Shimomura, Microporous "Honeycomb" Films Support Enhanced Bone Formation in Vitro Tissue Engineering A, 19, 2087-2096, 2013.
  63. T. Hoshiba, M. Tanaka, Breast cancer cell behaviors on staged tumorigenesis-mimicking matrices derived from tumor cells at various malignant stages, Biochemical and Biophysical Research Communications, 439, 291-296, 2013.
  64. M. Tanaka, T. Hayashi, S. Morita, The roles of water molecule at the biointerface of medical polymers, Polym. J., 45, 701-710, 2013. (Invited paper: SPSJ Asahi Kasei Award).


  65. T. Hayashi, Y. Tanaka, Y. Koide, M. Tanaka, M. Hara, Mechanism Underlying Bioinertness of Self-assembled Monolayers of Oligo(ethyleneglycol)-terminated Alkanethiols on Gold: Protein Adsorption, Platelet Adhesion, and Surface Forces, Physical Chemistry Chemical Physics, 14,10194-10206, 2012.
  66. I. Javakhishvili, M. Tanaka, K. Ogura, K. Jankova, S. Hvilsted, Synthesis of graft copolymers based on poly(2-methoxyethyl acrylate) and investigation of the associated water structure, Macromol. Rapid Commun., 33, 319-325, 2012.
  67. T. Hatakeyama, A. Kishi, M. Tanaka, Comparison of measurement techniques for the identification of bound water restrained by polymers, Thermochim Acta, 532, 159-163, 2012.


  68. M. Tanaka, Design of Novel 2D and 3D Bio-Interfaces using Self-Organization to Control Cell behavior, Nanotechnologies: Emerging Applications in Biomedicine, Biochimica et Biophysica Acta (BBA) - General Subjects, 1810, 251-258, 2011.
  69. T. Hirata, H. Matsuno, M. Tanaka, K. Tanaka, Surface Segregation of Poly(2-methoxyethyl acrylate) in a Mixture with Poly(methyl methacrylate), Physical Chemistry Chemical Physics, 13, 4928-4934, 2011.
  70. Y. Miwa, M. Tanaka, A. Mochizuki, Analyses of Water structures and dynamics of swollen blood compatible polymers, Koubunshi Ronbunshu, 68, 133-146, 2011.


  71. M. Tanaka, A. Mochizuki, Clarification of the Blood Compatibility Mechanism by Controlling the Water Structure at the Blood–Poly(meth)acrylate Interface, J. Biomat. Sci. Polym. Ed., 21, 1849-1863, 2010.
  72. T. Sato, M. Tanaka, S. Yamamoto, E. Ito, K. Shimizu, Y. Igarashi, M. Shimomura, J. Inokuchi, Effect of Honeycomb-Patterned Surface Topography on the Function of Mesenteric Adipocytes, J. Biomat. Sci. Polym. Ed., 21, 1947-1956, 2010.
  73. S. Morita, M. Tanaka, K. Kitagawa, Y. Ozaki, Hydration structure of poly(2-methoxyethyl acrylate): comparison with a 2-methoxyethyl acetate model monomer, J. Biomat. Sci. Polym. Ed., 21, 1925-1935, 2010.
  74. Y. Miwa, H. Ishida, M. Tanaka, A. Mochizuki, 2H-NMR and 13C-NMR Study of the Hydration Behavior of Poly(2-methoxyethyl acrylate), Poly(2-hydroxyethyl methacrylate) and Poly(tetrahydrofurfuryl acrylate) in Relation to Their Blood Compatibility as Biomaterials, J. Biomat. Sci. Polym. Ed., 21, 1911-1924, 2010.
  75. T. Hatakayama, M. Tanaka, H. Hatakayama, Thermal Properties of Freezing Bound Water Restrained by Polysaccharides, J. Biomat. Sci. Polym. Ed., 21, 1865-1880, 2010.
  76. A. Mochizuki, M. Kimura, A. Ina, Y. Tomono, M.Tanaka, Study on water structure and blood compatibility of poly(acryloylmorpholine-r-butyl methacrylate), J. Biomat. Sci. Polym. Ed., 21, 1895-1910, 2010.
  77. T. Hatakayama, M. Tanaka, H. Hatakayama, Studies on bound water restrained by poly(2-methacryloyloxyethyl phosphorylcholine) (PMPC): Comparison of the polysaccharides-water systems, Acta Biomaterialia, 6, 2077-2082, 2010.
  78. H. Ishihata, M. Tanaka, N. Iwama, M. Ara, M. Shimonishi, M. Nagamine, N. Murakami, S. Kanaya, E. Nemoto, H. Shimauchi, M. Shimomura, Proliferation of periodontal ligament cells on biodegradable honeycomb film scaffold with unified micropore organization, Journal of Biomechanical Science and Engineering, Special Issue on Micro and Nanobiotechnology for Cells, 5, 252-261, 2010.
  79. Y. Uraki, C. Matsumoto, T. Hirai, Y. Tamai, M. Enoki, H. Yabu, M. Tanaka, M. Shimomura, Mechanical effect of acetic acid lignin adsorption on honeycomb-patterned cellulosic films, Journal of Wood Chemistry and Technology, 30, 348-359, 2010.


  80. M. Tanaka, M. Takebayashi, M. Shimomura, Fabrication of ordered arrays of biodegradable polymer pincushions using self-organized honeycomb-patterned film, Macromol .Symp., (Invited original paper). 279, 175-182, 2009.
  81. M. Tanaka, H. Sato, Y. Sasaya, S. Horinouchi, J. Hotta, Y. Matsuo, K. Ijiro, K. Sasaki, M. Shimomura, Fabrication of Novel Biocompatible Surfaces by Two-Photon Absorption Technique Using Femtosecond Laser, Mol. Cryst. Liq. Cryst., 505, 219-230, 2009.
  82. Y. Miwa, H.Ishida, H.Saitô, M. Tanaka, A. Mochizuki, Network structures and dynamics of dry and swollen poly(acrylate)s. Characterization of high- and low-frequency motions as revealed by suppressed or recovered intensities (SRI) analysis of 13C NMR, Polymer, 50, 6091- 6099, 2009.
  83. A. Mochizuki, T. Hatakeyama, Y. Tomono, M. Tanaka, Water structure and blood compatibility of poly(tetrahydrofurfuryl acrylate). J. Biomat. Sci. Polym. Ed., 20, 591-603, 2009.
  84. A. Mochizuki, A. Kishi, M. Tanaka, Comparative study on water structures in polyHEMA and polyMEA by XRD-DSC simultaneous measurement, J. Appl. Poly. Sci., 111, 476-481, 2009.
  85. Y. M. Chen, J. P. Gong, M. Tanaka, K. Yasuda, S. Yamamoto, M. Shimomura, Y. Osada, Tuning of cell proliferation on tough gels by critical charge effect, J. Biomed. Mater. Res. A, 88A, 74-83, 2009.
  86. S. Tada, C. Inaba, K. Mizukami, S. Fujishita, M. Gemmei-Ide, H. Kitano, A. Mochizuki, M. Tanaka, T. Matsunaga, Anti-Biofouling Properties of Polymers with a Carboxybetaine Moiety. Macromolecular Bioscience, 9(1), 63-70, 2009.


  87. M. Tanaka, K. Yoshizawa, A. Tsuruma, H. Sunami, S. Yamamoto, M. Shimomura, Formation of hydroxyapatite on a self-organized 3D honeycomb-patterned biodegradable polymer film, Colloids and Surfaces A: Physicochemical and Engineering Aspects, 313-314, 515-519, 2008.
  88. K Arai, M. Tanaka, S. Yamamoto, M. Shimomura, Effect of pore size of honeycomb films on the morphology, adhesion and cytoskeletal organization of cardiac myocytes, Colloids and Surfaces A: Physicochemical and Engineering Aspects, 313-314, 530-535, 2008.
  89. A. Tsuruma, M. Tanaka, S. Yamamoto, M. Shimomura, Control of neural stem cell differentiation on honeycomb films, Colloids and Surfaces A: Physicochemical and Engineering Aspects, 313-314, 536-540, 2008.
  90. A. Tanabe, S. Morita, M. Tanaka, I. Noda, Y. Ozaki, Multivariate Curve Resolution Analysis on Multi-Component Water Sorption Process into a Poly(2-methoxyethyl acrylate) Film, Appl. Spec., 62, 46-50, 2008.
  91. H. Kitano, K. Nagaoka, S. Tada, M. Gemmei-Ide, M. Tanaka, Structure of Water Incorporated in Amphoteric Polymer Thin Films as Revealed by FT-IR Spectroscopy, Macromolecular Bioscience, 8, 77-85, 2008.
  92. Y. Fukuhira, M. Ito, H. Kaneko, Y. Sumi, M. Tanaka, S. Yamamoto, M. Shimomura, Prevention of postoperative adhesions by honeycomb-patterned poly(lactide)film in rat experimental model, J. Biomed. Mater. Res. B, 86B, 353-359, 2008.
  93. A. Nogami, E. Tominaga, Y. Sawa, T. Murata, Y. Kudo, M.Tanaka, M.Shimomura, Development of the honeycomb film filter for individual aerosol particle analysis, Earozoru Kenkyu, 23(2), 127-133, 2008.
  94. S. Tsukiyama, M. Matsushita, M. Tanaka, H. Tamura, S. Todo, S. Yamamoto, M. Shimomura, Enhanced cell survival and yield of rat small hepatocytes by honeycomb-patterned films, Jp. J. Appl. Phys., Vol. 47, No. 2, 1429-1434, 2008.
  95. Y. Fukuhira, H. Kaneko, M. Yamaga, M. Tanaka, S. Yamamoto, M. Shimomura, Effect of honeycomb-patterned structure on chondrocyte behavior in vitro, Colloids and Surfaces A: Physicochemical and Engineering Aspects, 313-314, 520-525, 2008.


  96. M. Tanaka, A. Takayama, E. Ito, H. Sunami, S. Yamamoto M. Shimomura, Effect of pore size of self-organized honeycomb-patterned polymer films on spreading, focal adhesion, proliferation, and function of endothelial cells, J. Nanosci. Nanotech., 7, 763-772, 2007.
  97. S. Yamamoto, M. Tanaka, E. Ito, Y. Morita , H. Sunami, K. Ijiro, M. Shimomura, The influence of pore size of a honeycomb film on early spreading process of endtherial cells, J. Surf. Sci. Soc. Jap., 28(8), 433-439, 2007.
  98. T. Okajima, M. Tanaka, S. Tsukiyama, T. Kadowaki, S. Yamamoto, M. Shimomura, H. Tokumoto, Stress Relaxation and Fluctuation of Living Cells Measured by Atomic Force Microscopy, Jp. J. Appl. Phys., 46 (8B), 5552-5555, 2007.
  99. S. Yamamoto, M. Tanaka, H. Sunami, S. Yamashita, Y. Morita, M. Shimomura, Effects of honeycomb-patterned surface topography on the adhesion and signal transduction of porcine aortic endothelial cells, Langmuir, 23, 8114-8120, 2007.
  100. J.R. McMillan, M. Akiyama, M. Tanaka, S. Yamamoto, M. Goto, R. Abe, D. Sawamura, M. Shimomura, H. Shimizu, Small-diameter porous poly (epsilon-caprolactone) films enhance adhesion and growth of human cultured epidermal keratinocyte and dermal fibroblast cells., Tissue Engineering, 13, 789-798, 2007.
  101. Y. M. Chen, M. Tanaka, JP Gong, K Yasuda, S. Yamamoto, M. Shimomura, Y. Osada, Platelet adhesion to human umbilical vein endothelial cells cultured on anionic hydrogel scaffolds, Biomaterials, 28, 1752-1760, 2007.
  102. T. Okajima, M. Tanaka, S. Tsukiyama, T. Kadowaki, S. Yamamoto, M. Shimomura, H. Tokumoto, Stress relaxation of HepG2 cells measured by atomic force microscopy, Nanotechnology, 18, 084010-4, 2007.
  103. S. Morita, M. Tanaka, Y. Ozaki, Time-Resolved In-Situ ATR-IR Observations of Water Sorption Process into a Poly(2-methoxyethyl acrylate) (PMEA) Film, Langmuir, 23, 3750-3761, 2007.
  104. T. Hayashi, M. Tanaka, S. Yamamoto, M. Shimomura, M. Hara, Direct observation of biocompatibility of  PMEA(poly(2-methoxyethyl acrylate)) using Atomic Force Microscopy, Biointerphases, 2(4), 1-9 , 2007.
  105. S. Morita, M. Tanaka, I. Noda, Y. Ozaki, Phase Angle Description of Perturbation Correlation Analysis and Its Application to Time-Resolved IR Spectra, Appl. Spec.,61(8), 867-872, 2007.
  106. E. Hirota, M. Tanaka, A. Mochizuki, Blood Compatibility and Water Structure-Comparative Study between 2-Methoxyethylacrylate- and 2-Methoxyethylmethacrylate-based random copolymers, J. Biomed. Mater. Res. 81A, 710-719, 2007.
  107. Y. Uraki, J. Nemoto, H. Otsuka, Y. Tamai, J. Sugiyama, T. Kishimoto, M. Ubukata, H. Yabu, M. Tanaka, M. Shimomura, Honeycomb-Like Architecture Produced by Living Bacteria, Gluconacetobacter xylinus, Carbohydrate Polymers, 69, 1-6, 2007.
  108. T. Hatakeyma, H. Kasuga, M. Tanaka, H. Hatakeyama, Cold crystallization of poly(ethylene glcyol)-water systems, Thermochim Acta, 465, 59-66, 2007.


  109. S. Yamamoto, M. Tanaka, H. Sunami, S. Yamashita, Y. Morita, M. Shimomura, Relationship between adsorbed fibronectin and cell adhesion on a honeycomb-patterned film, Surf. Sci., 600, 3785-3791, 2006.
  110. M. Tanaka, K. Nishikawa, H. Okubo, H. Kamachi, T. Kawai, M. Matsushita, S. Todo, M. Shimomura, Control of hepatocyte adhesion and function on self-organized honeycomb-patterned polymer film, Colloids and Surfaces A: Physicochemical and Engineering Aspects, 284-285, 464-469, 2006.
  111. A. Tsuruma, M. Tanaka, S. Yamamoto, N. Fukushima, H. Yabu, M. Shimomura, Topographical control of neurites extension on stripe-patterned polymer films, Colloids and Surfaces A: Physicochemical and Engineering Aspects, 284-285, 470-474, 2006.
  112. S. Yamamoto, M. Tanaka, H. Sunami, S. Yamashita, Y. Morita, M. Shimomura, Relationship between Adsorbed Fibronectin and Cell Adhesion on a Honeycomb-patterned Film, J. Surf. Sci. Soc. Jap., 27(10), 2006.
  113. H. Sunami, E. Ito, M. Tanaka, S.Yamamoto, M. Shimomura, Effect of honeycomb film on protein adsorption, cell adhesion and proliferation. Colloids and Surfaces A: Physicochemical and Engineering Aspects, 284-285, 548-551, 2006.
  114. Y. Fukuhira, E. Kitazono, T. Hayashi, H. Kaneko, M. Tanaka, M. Shimomura, Y. Sumi, Biodegradable honeycomb-patterned film composed of poly(lactic acid) and dioleoylphosphatidylethanolamine, Biomaterials, 27, 1797-1802, 2006.
  115. E. Hirota, K. Ute, M. Uehara, T. Kitayama, M. Tanaka, A. Mochizuki, -Study of Blood Compatibility with Poly(2-Methoxyethylacrylate) - Relationship between Surface Structure, Water Structure and Platelet Compatibility in 2-Methoxyethylacrylate/2-Hydroxyethylmethacrylate Diblock Copolymer, J. Biomed. Mater. Res., 76A, 540-550, 2006.
  116. M. Shimomura, A. Tsuruma, M. Tanaka, H. Sunami, S. Yamamoto, Biomedical application of patterned polymer films prepared by self-organization, J. Surf. Sci. Soc. Jap., 27, 170-175, 2006.


  117. A. Tsuruma, M. Tanaka, N. Fukushima, M. Shimomura, Morphological changes in neurons by self-organized patterned films, e-J. Surf. Sci. Nanotech., 3, 159-164, 2005.
  118. H. Kitano, T. Mori, Y. Takeuchi, S. Tada, M. Gemmei-ide, Y. Yokoyama, M. Tanaka, Structure of Water Incorporated in Sulfobetaine Polymer Films as Studied by ATR-FTIR, Macromol. Biosci., 5(4), 314-321, 2005.
  119. J. Nemoto, Y. Uraki, T. Kishimoto, Y. Sano, R. Funada, N. Obata, H. Yabu, M. Tanaka, M. Shimomura, Production of mesoscopically patterned cellulose film, Bioresource Technol, 96(17), 1955-1958, 2005.
  120. H. Kitano, S. Tada, T. Mori, K. Takaha, M. Gemmei-Ide, M. Tanaka, M. Fukuda, Y. Yokoyama, Correlation between the Structure of Water in the Vicinity of Carboxybetaine Polymers and Their Blood-Compatibility, Langmuir, 21, 11932-11940, 2005.
  121. H. Yabu, M. Takebayashi, M. Tanaka, M. Shimomura, Superhydrophobic and Lipophobic Properties of Self-Organized Honeycomb and Pincushion Structures, Langmuir, 21(8), 3235-3237, 2005.

    2004 and earlier (Peer-reviewed)

  122.  A. Tsuruma, M. Tanaka, N. Fukushima, M. Shimomura, Control of neurites extension by self-organized patterned polymer films, Koubunshi Ronbunshuu, 61(12), 628-633, 2004.
  123. G. Li, S. Morita, S. Ye, M. Tanaka, M. Osawa, Bisphenol QCM and IRRAS Characterization of Bisphenol A Absorption in the Poly(acrylate) Thin Films, Anal. Chem.76, 788-795, 2004.
  124. M. Tanaka, A. Mochizuki, Effect of water structure on blood compatibility-Thermal analysis of water in poly(meth)acrylate-, J. Biomed. Mater. Res., 68A(3), 684-695, 2004.
  125. M. Tanaka, Design of Novel BioInterfaces (I) -Blood compatibility of poly(2-methoxyethyl acrylate)-, Bio-Med. Mater. Eng., 14, 427-438, 2004.
  126. M. Tanaka, M. Takebayashi, M. Miyama, J. Nishida, M. Shimomura, Design of Novel BioInterfaces (II) -Fabrication of self-organized porous polymer film with highly uniform pores-, Bio-Med. Mater. Eng., 14, 439-446, 2004.
  127.  M. Ide, T. Mori, K. Ichikawa, H. Kitano, M.Tanaka, A. Mochizuki, H. Oshiyama, W. Mizuno, Structure of Water Sorbed into Poly(MEA-co-HEMA) Films As Examined by ATR-IR Spectroscopy, Langmuir, 19, 429-435, 2003.
  128. M. Tanaka, Blood Compatibility of Poly(2-methoxyethyl acrylate) - Design of Novel Biointerfaces, Koubunshi Ronbunshuu, 60(8), 415-427, 2003.
  129. S. Ye, S. Morita, G. Li, H. Noda, M. Tanaka, K. Uosaki, M. Osawa, Interfacial Molecular Structure Changes in Poly(2-methoxyethyl acrylate) Thin Films Induced by Absorption of Bisphenol A. An Infrared and Sum Frequency Generation (SFG) Study, Macromolecules, 36, 5694-5703, 2003.
  130. H. Yabu, M. Tanaka, K. Ijiro, M. Shimomura, Preparation of honeycomb patterned polyimide films by self-organization, Langmuir, 19, 6297-6300, 2003.
  131. M. Tanaka, A. Mochizuki, N. Ishii, T. Motomura, T. Hatakeyama, Study of Blood Compatibility With poly(2-methoxyethyl Acrylate). Relationship Between Water Structure and Platelet Compatibility in poly(2-methoxyethylacrylate-co- 2-hydroxyethylmethacrylate), Biomacromolecules, 3, 36-41, 2002.
  132. M. Tanaka, A. Mochizuki, T. Shiroya, T. Motomura, K. Shimura, M. Onishi, Y. Okahata, Study on kinetics of early stage protein adsorption on poly(2-methoxyethylacrylate) (PMEA) surface. Colloids and Surfaces A: Physicochemical and Engineering Aspects, 203, 195-204, 2002.
  133. K. Sato, M. Tanaka, K. Hasebe, M. Takebayashi, K. Nishikawa, T. Kawai, M. Matsushita, S. Todo, M. Shimomura, Preparation of the honeycomb patterned porous film of biodegradable polymer for tissue engineering scaffolds, Inter. J. Nanosci., 1(5,6), 689-693, 2002.
  134. M.Tanaka, A. Mochizuki, T. Motomura, K. Shimura, M. Onishi, Y. Okahata. In Situ Studies on Protein Adsorption onto a Poly(2-methoxyethyl acrylate) Surface by a Quartz Crystal Microbalance. Colloids and Surfaces A: Physicochemical and Engineering Aspects, 193, 145-152, 2001.
  135. H. Kitano, K. Ichikawa, M. Fukuda, A. Mochizuki, M. Tanaka, The Structure of Water Sorbed to Polymethylmethacrylate Film As Examined by FT-IR Spectroscopy, J. Colloid Surface Sci., 242, 133-140, 2001.
    DOI: 10.1006/jcis.2001.7785
  136. K. Ichikawa, T. Mori, H. Kitano, M. Fukuda, A. Mochizuki, M. Tanaka, A FT-IR Study on the Sorption of Water to Various Kinds of Polymer Thin Films, J. Polym. Sci., B Polym. Phys. 39, 2175-2182, 2001.
  137. L. Schiel, S. Burns, A. Nogawa, R. Rice, T. Anzai, M. Tanaka, X-Coating : A New Biopassive Polymer Coating, Canadian Perfusion Canadienne, 11(2), 8-17, 2001.
  138. M. Tanaka, T. Motomura, N. Ishii, K. Shimura, M. Onishi, A. Mochizuki, T. Hatakeyama, Cold crystallization of water in hydrated Poly(2-methoxyethyl acrylate) (PMEA), Polymer International, 49, 1709-1713, 2000.
  139. M. Tanaka, T. Motomura, M. Kawada, T. Anzai, Y. Kasori, T. Shiroya, K. Shimura, M. Onishi, A. Mochizuki, Y. Okahata, A new blood-compatible surface prepared by Poly(2-methoxyethyl acrylate) (PMEA) coating -Protein adsorption on PMEA surface-, Jpn. J.Art. Org, 29, 209-216, 2000.
  140. M. Tanaka, T. Motomura, M. Kawada, T. Anzai, Y. Kasori, T. Shiroya, K. Shimura, M. Onishi, A. Mochizuki, Blood compatible aspects of Poly(2-methoxyethylacrylate) (PMEA) -Relationship between protein adsorption and platelet adhesion on PMEA surface-, Biomaterials, 21, 1471-1481, 2000.
  141.  M.Shimomura, F.Nakamura, K.Ijiro, H.Taketsuna, M.Tanaka, H.Nakamura, K.Hasebe, Two-dimrnsional DNA-mimetic monolayer organization at the air-water interface, J. Am. Chem. Soc., 119, 2341-2342, 1997.
  142. K.Ijiro, M.Shimomura, M.Tanaka, H.Nakamura, K.Hasebe, DNA monolayers complexed with amphiphilic intercalator at the air water interface, Thin Solid Films, 284-285, 780-783, 1996.
  143. M.Shimomura, F.Nakamura, K.Ijiro, H.Taketsuna, M.Tanaka, H.Nakamura, K.Hasebe, Chiral crystal formation of octadecylcytosine monolayer by complementary base-paring, Thin Solid Films, 284-285691-693, 1996.

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