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業績紹介(論文)


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原著論文

2020

  1. A.-T. Kuo, T. Sonoda, S. Urata, R. Koguchi, S. Kobayashi, M. Tanaka, Elucidating the Feature of Intermediate Water in Hydrated Poly(ω-methoxyalkyl acrylate)s by Molecular Dynamics Simulation and Differential Scanning Calorimetry Measurement, ACS Biomater. Sci. Eng., in press (2020).
    DOI: 10.1021/acsbiomaterials.0c00746
  2. R. Koguchi, K. Jankova, Y. Hayasaka, D. Kobayashi, Y. Amino, T. Miyajima, S. Kobayashi, D. Murakami, K. Yamamoto, M. Tanaka, Understanding the effect of hydration on the bio-inert properties of HEMA copolymers with small amounts of amino- or/and fluorine-containing monomers, ACS Biomater. Sci. Eng., 6, 2855-2866 (2020).
    DOI: 10.1021/acsbiomaterials.0c00230
  3. M-Y. Tsai, F. Aratsu, S. Sekida, S. Kobayashi, M. Tanaka, Blood-compatible poly(2-methoxyethyl acrylate) induces blebbing-like phenomenon and promotes viability of tumor cells in serum-free medium, ACS Applied Bio Materials, 31858-1864 (2020).
    DOI: 10.1021/acsabm.9b00885
  4. D. Murakami, Y. Segami, T. Ueda, M. Tanaka, Control of interfacial structures and anti-platelet adhesion property of blood-compatible random copolymers, J. Biomater. Sci. Polym. Ed., 31, 207-218 (2020).
    DOI: 10.1080/09205063.2019.1680930
  5. M. Watanabe, Y. Tanaka, D. Murakami, M. Tanaka, M. Kawai, T. Mitsumata, Optimal plasticizer content for magnetic elastomers used for cell culture, Chemistry Letters, 49, 280-283 (2020).
    DOI: 10.1246/cl.190929

    2019

  6. M. Tanaka, S. Kobayashi, D. Murakami, F. Aratsu, A. Kashiwazaki, T. Hoshiba, K. Fukushima, Design of Polymeric Biomaterials: The “Intermediate Water Concept”, Bull. Chem. Soc. Jpn., 92, 2043-2057 (2019).
    DOI: 10.1246/bcsj.20190274
  7. K. Jankova, I. Javakhishvili, S. Kobayashi, R. Koguchi, D. Murakami, T. Sonoda, M. Tanaka, Hydration states and blood compatibility of Hydrogen-bonded supramolecular poly(2-methoxyethyl acrylate), ACS Appl. Bio Mater., 2, 4154-4161 (2019).
    DOI: 10.1021/acsabm.9b00363
  8. T. Araki, F. Yoshida, T. Uemura, Y. Noda, S. Yoshimoto, T. Kaiju, T. Suzuki, H. Hamanaka, K. Baba, H. Hayakawa, T. Yabumoto, H. Mochizuki, S. Kobayashi, M. Tanaka, M. Hirata, T. Sekitani, Long-term implantable, flexible, and transparent neural interface based on Ag/Au core-shell nanowires, Adv. Healthcare Mater., 8, 1900130 (2019).
    DOI: 10.1002/adhm.201900130
  9. R. Koguchi, K. Jankova, N. Tanabe, Y. Amino, Y. Hayasaka, D. Kabayashi, T. Miyajima, K. Yamamoto, M. Tanaka, Controlling the hydration structure with small amount of fluorine to produce blood compatible fluorinated poly(2-methoxyethyl acrylate), Biomacromolecules, 20, 2265-2275 (2019).
    DOI: 10.1021/acs.biomac.9b00201
  10. A.-T. Kuo, S. Urata, R. Koguchi, K. Yamamoto, M. Tanaka, Analyses of Equilibrium Water Content and Blood Compatibility for Poly(2-methoxyethyl acrylate) by Molecular Dynamics Simulation, Polymer, 170, 76-84 (2019).
    DOI: 10.1016/j.polymer.2019.03.001
  11. M. Okada, E. Hara, D. Kobayashi, S. Kai, K. Ogura, M. Tanaka, T. Matsumoto, Intermediate water on calcium phosphate minerals: its origin and role in crystal growth, ACS Applied Bio Materials, 2, 981-986 (2019).
    DOI: 10.1021/acsabm.9b00014
  12. D. Murakami, N. Mawatari, T. Sonoda, A. Kashiwazaki, M. Tanaka, Effect of Molecular Weight of Poly(2-methoxyethylacrylate) on Interfacial Structure and Blood Compatibility. Langmuir, 35, 2808-2813 (2019).
    DOI: 10.1021/acs.langmuir.8b02971

    2018

  13. W. Lee, S. Kobayashi, M. Nagase, Y. Jimbo, I. Saito, Y. Inoue, T. Yambe, M. Sekino, G. G Malliaras, T. Yokota, M. Tanaka, T. Someya, A Nonthrombogenic, Stretchable, Active Multielectrode Array using Organic Electrochemical Transistors, Science Advances, 4(10), eaau2426 (2018).
    DOI: 10.1126/sciadv.aau2426
  14. T.Ueda, D. Murakami, M. Tanaka. Analysis of interaction between interfacial structure and fibrinogen at blood-compatible polymer/water interface. Frontiers in Chemistry, Polymer Surface Chemistry: Biomolecular Engineering and Biointerfaces, 6, 542 (2018).
    DOI: 10.3389/fchem.2018.00542
  15. F. Khan, F. Aratsu, S. Kobayashi, M. Tanaka, A Simple Strategy for Robust Hydrogel Preparation and Characterisation Derived from Chitosan and Amino Functional Monomers for Biomedical Applications, Journal of Materials Chemistry B, 6, 5115-5129 (2018).
    DOI: 10.1039/C8TB00865E
  16. D. Murakami, Y. Kitahara, S. Kobayashi, M. Tanaka, Thermosensitive Polymer Biocompatibility based on Interfacial Structure at BiointerfaceACS Biomaterials Science & Engineering, 4, 1591-1597 (2018). 
    DOI10.1021/acsbiomaterials.8b00081
  17. M. Mabrouk, H. H.  Beherei, S. ElShebiney, M. Tanaka, Newly developed controlled release subcutaneous formulation for tramadol hydrochloride, Saudi Pharmaceutical Journal, 26, 585-592 (2018).
    DOI: 10.1016/j.jsps.2018.01.014
  18. F. Khan, M. Tanaka, Designing Smart Biomaterials for Tissue Engineering, International Journal of Molecular Sciences, 19(1), 17 (2018). 
    DOI10.3390/ijms19010017
  19. T. Hoshiba, K. Sato, N. Kawazoe, G. CHEN, M. Tanaka, Chondrocyte shapes and detachment on a thermo-responsive poly (2-methoxyethyl acrylate) analog for the development of new chondrocytes subculture substrate, Chemistry Letters, 47(1), 107-109 (2018).
    DOI10.1246/cl.170889

    2017

  20. S. Kobayashi, M. Wakui, Y. Iwata, M. Tanaka, Poly(ω-methoxyalkyl acrylate)s: A nonthrombogenic polymer family with tunable protein adsorption, Biomacromolecules, 18 (12), 4214-4223 (2017).
    DOI10.1021/acs.biomac.7b01247
  21. K. Fukushima, Y. Inoue, Y. Haga, T. Ota, K. Honda, C. Sato, M. Tanaka, Monoether-tagged Biodegradable Polycarbonate Preventing Platelet Adhesion and Demonstrating Adhesion of Vascular Cells: A Promising Material for Resorbable Vascular Grafts and Stents, Biomacromolecules18 (11), 3834–3843 (2017).
    DOI: 10.1021/acs.biomac.7b01210
  22. T. Hoshiba, H. Maruyama, K. Sato, C. Endo, N. Kawazoe, G. Chen, M. Tanaka, Maintenance of Cartilaginous Gene Expression of Serially Subcultured Chondrocytes on Poly(2-Methoxyethyl Acrylate) Analogous Polymers, Macromol. Biosci.,17,170297(2017) .
    DOI: 10.1002/mabi.201700297
  23. K. Fukushima, K. Honda, Y. inoue, M. Tanaka, Synthesis of Antithrombotic Poly(carbonate-urethane)s through a Sequential Process of Ring-Opening Polymerization and Polyaddition Facilitated by Organocatalysts, Eur. Polym. J., Vol. 95,  728-736 (2017).
    DOI: 10.1016/j.eurpolymj.2017.07.001
  24. K. Sato, S. Kobayashi, A. Sekishita, M. Wakui, M. Tanaka, Synthesis and Thrombogenicity Evaluation of Poly(3-methoxypropionic acid vinyl ester): a candidate for blood compatible polymer, Biomacromolecules, 18, 1609-1616 (2017).
    DOI: 10.1021/acs.biomac.7b00221
  25. T. Hoshiba, A.Yoshihiro, M. Tanaka, Evaluation of initial cell adhesion on poly (2-methoxyethyl acrylate) (PMEA) analogous polymers, J. Biomat. Sci. Polym. Ed., 28, 986-999 (2017).
    DOI: 10.1080/09205063.2017.1312738
  26. T. Sekine, S. Asatyas, C. Sato, S. Morita, M. Tanaka, T. Hayashi, Surface force and vibrational spectroscopic analyses of interfacial water molecules in the vicinity of methoxy-tri(ethylene glycol)-terminated monolayers: mechanisms underlying the effect of lateral packing density on bioinertness, J. Biomat. Sci. Polym. Ed., 28, 1231-1243 (2017).
    DOI: 10.1159/000451043
  27. Y. Inoue,  T. Yokota, T. Sekitani, A. Kaneko, T. Woo, S. Kobayashi, T.Shibuya, M. Tanaka, H. Koshukegawa, I. Saito, T. Isoyama, Y. Abe, T.Yambe, T. Someya, M. Sekino, Antithrombotic Protein Filter Composed of Hybrid Tissue-Fabric Material has a Long Lifetime, Annals of Biomedical Engineering, 45(5), 1352-1364 (2017).
    DOI: 10.1007/s10439-016-1781-5
  28. T. Hirata, H. Matsuno, D. Kawaguchi, M. Inutsuka, T. Hirai, M. Tanaka, K. Tanaka, Dynamics of a bioinert polymer in hydrated states by dielectric relaxation spectroscopy, Physical Chemistry Chemical Physics, 19,1389-1394 (2017).
    DOI: 10.1039/c6cp07322k

    2016

  29. T. Hoshiba, E. Nemoto, K. Sato, H. Maruyama, C. Endo, M. Tanaka, Promotion of adipogenesis of 3T3-L1 cells on protein adsorption-suppressing poly (2-methoxyethyl acrylate) analogous polymers, Biomacromolecules, 17,3808-3815 (2016).
    DOI:
    10.1021/acs.biomac.6b01340
  30. D. Murakami, S. Kobayashi, M. Tanaka, Interfacial Structures and Fibrinogen Adsorption at Blood-Compatible Polymer/Water Interfaces, ACS Biomater. Sci. Eng., 2, 2122–2126 (2016).
    DOI:0.1021/acsbiomaterials.6b00415
  31. K. Osawa, S. Kobayashi, M. Tanaka, Synthesis of Sequence-Specific Polymers with Amide Side-chains via Regio-/stereoselective Ring-opening Metathesis Polymerization of 3-Substituted cis-Cycloocte, Macromolecules, 49, 8154-8161 (2016).
    DOI:10.1021/acs.macromol.6b01829
  32. T. Hoshiba, M. Tanaka, Integrin-independent cell adhesion substrates:Possibility of applications for mechanobiology research, Special Issue:Mechanobiology, Analytical Sciences, 32,1151-1158 (2016).
    DOI:10.1021/acs.macromol.6b01829
  33. T. Hoshiba, T. Orui, C. Endo, K. Sato, A. Yoshihiro, Y. Minagawa, M.Tanaka, Adhesion-Based Simple Capture and Recovery of Circulating Tumor Cells Using a Blood-Compatible and Thermo-Responsive Polymer-Coated Substrate, RSC Advances, 6, 89103-89112 (2016).
    DOI:10.1039/C6RA15229E
  34. A. Basterretxea, Y. Haga, A. Sanchez-Sanchez, M. Isik, L. Irusta, M. Tanaka, K. Fukushima, H. Sardon, Biocompatibility and hemocompatibility evaluation of polyether urethanes synthesized using DBU organocatalyst, Eropean Polymer Journal, 84, 750-758 (2016).
    DOI:10.1016/j.eurpolymj.2016.08.008
  35. T. Hoshiba, M.Tanaka, Decellularized matrices as in vitro models of extracellular matrix in tumor tissues at different malignant levels:Mechanism of 5-fluorouracil resistance in colorectal tumor cells, BBA - Molecular Cell Research, 1863,2749-2757 (2016).
    DOI:10.1016/j.bbamcr.2016.08.009.
  36. K. Kono, H. Hiruma, S. Kobayashi, Y. Sato,  M.Tanaka, R. Sawada, S. Niimi, In vitro endothelialization test of biomaterials using immortalized endothelial cells, PLoS One, 11(6), e01582898 (2016).
    DOI:10.1371/journal.pone.0158289
  37. S. Kobayashi, K. Fukuda, M. Kataoka, M. Tanaka, Regioselective Ring-Opening Metathesis Polymerization of 3-Substituted Cyclooctenes with Ether Side-Chains, Macromolecules, 49(7), 2493-2501 (2016).
    DOI:10.1021/acs.macromol.6b00273
  38. C. Sato, M. Aoki, M. Tanaka, Blood-compatible poly(2-methoxyethyl acrylate) for the adhesion and proliferation of endothelial and smooth muscle cells, Colloids and Surfaces B: Biointerfaces,145, 586-596 (2016).
    DOI:10.1016/j.colsurfb.2016.05.057
  39. T. Hoshiba, M. Nikaido, S.Yagi, I. Konno, A. Yoshihiro, M. Tanaka, Blood-compatible poly (2-methoxyethyl acrylate) for the adhesion and proliferation of lung cancer cells toward the isolation and analysis of circulating tumor cells, Journal of Bioactive and Compatible Polymers, 31, 361-372 (2016).
    DOI:10.1177/0883911515618976
  40. H. Choi, M. Tanaka, K. Sugimoto, Difference in cell proliferation and spontaneous mediator release between two mast cell lines, NCL-2 and RBL-2H3 on honeycomb-like structured film, Journal of Nanotechnology: Nanomedicine & Nanobiotechnology, 3(009) (2016).
    DOI:10.24966/NTMB-2044/100009
  41.  T. Hoshiba, G. Chen, C. Endo, H. Maruyama, M. Wakui, E. Nemoto, N. Kawazoe, M. Tanaka. Decellularized extracellular matrix (ECM) as an in vitro model to study the comprehensive roles of the ECM in stem cell differentiation. Stem Cells Int., 2016, 6397820 (2016).
    DOI:10.1155/2016/6397820

    2015

  42. T. Hoshiba, T. Otaki, E. Nemoto, H. Maruyama, M. Tanaka. Blood compatible polymer for hepatocyte culture with high hepatocyte-specific functions toward bioartificial liver development. ACS Appl. Mater. Interfaces 7, 18096-18103 (2015).
    DOI:10.1021/acsami.5b05210
  43. T. Hirata, H. Matsuno, D. Kawaguchi, N. Yamada, M. Tanaka, K. Tanaka, Construction of a blood-compatible interface based on surface segregation in a polymer blend, Polymer, 78, 219-224 (2015).
    DOI:10.1016/j.polymer.2015.10.001
  44. F. Khan, M. Tanaka, S.R. Ahmad, Fabrication of polymeric biomaterials: a strategy for tissue engineering and medical devices, Journal of Materials Chemistry B, 3, 8224-8249 (2015).
    DOI:10.1039/C5TB01370D
  45. T. Hoshiba, E. Nemoto, K. Sato, T. Orui, T. Otaki, A. Yoshihiro, M. Tanaka. Regulation of the contribution of integrin to cell attachment on poly(2-methoxyethyl acrylate) (PMEA) analogous polymers for attachment-based cell enrichment. PLoS One,10, e0136066 (2015).
    DOI:10.1371/journal.pone.0136066
  46. T. Sekine, Y. Tanaka, C. Sato, M. Tanaka, T. Hayashi, Evaluation of factors to determine platelet compatibility by using self-assembled monolayers with a chemical gradient, Langmuir, 31,7100-7105 (2015).
    DOI:10.1021/acs.langmuir.5b01216
  47. K. Sato, S. Kobayashi, M. Kusakari, S. Watahiki, M. Oikawa, T. Hoshiba,  M. Tanaka, The relationship between water structure and blood compatibility in poly(2-methoxyethyl acrylate) (PMEA) analogues, Macromol. Biosci., 15, 1296-1303 (2015).
    DOI:10.1002/mabi.201500078
  48.  T. Hirata, H. Matsuno, D. Kawaguchi, N. Yamada, M. Tanaka, K. Tanaka, Effect of interfacial structure on bioinert property of poly(2-methoxyethyl acrylate)/ poly(methyl methacrylate) blend films in water, Phys. Chem. Chem. Phys., 17,17399-17405 (2015).
    DOI:10.1039/c5cp01972a
  49. K. Fukushima, M. Tsai, T. Ota, Y. Haga, K. Matsuzaki, Y. Inoue, M. Tanaka, Evaluation of the hemocompatibility of hydrated biodegradable aliphatic carbonyl polymers with a subtle difference in the backbone structure based on the intermediate water concept and surface hydration, Polym. J., 47, 469-473 (2015). 
    DOI:10.1038/pj.2015.22
  50. T. Hirata, H. Matsuno, D. Kawaguchi, T. Hirai, N. Yamada, M. Tanaka, K. Tanaka, Effect of Local Chain dynamics on a Bio-inert Interface, Langmuir, 31, 3661-3667 (2015).
    DOI:10.1021/acs.langmuir.5b00258
  51. M. Tanaka, K. Sato, E. Kitakami, S. Kobayashi, T. Hoshiba, K. Fukushima, Design of biocompatible and biodegradable polymers based on the intermediate water concept, Polymer Journal, 47, 114-121 (2015). Invited paper: Special Issue on Fusion Materials, Most Accessed Papers(September - December 2015)
    DOI:10.1038/pj.2014.129
  52. T. Hoshiba, M. Tanaka, Optimization of the tissue source, malignancy, and initial substrate of tumor cell-derived matrices to increase cancer cell chemoresistance against 5-fluorouracil. Biochem. Biophys.Res. Commun., 457, 353-357 (2015).
    DOI:10.1016/j.bbrc.2014.12.116

    2014

  53. S. Morita, M. Tanaka, Effect of Sodium Chloride on Hydration Structures of PMEA and P(MPC-r-BMA), Langmuir, 30,10698-10703 (2014).
    DOI:10.1021/la502550d
  54. K. Sugimoto, H. Choi, M. Tanaka, Honeycomb-like structured film regulates mediator release from non-tumor mast cells,  European Journal of Inflammation, 12, 515-520 (2014).
    DOI:10.1177/1721727X1401200313
  55. E. Kitakami, M. Aoki, C. Sato, H. Ishihata, M. Tanaka, Adhesion and proliferation of human periodontal ligament cells on poly(2-methoxyethyl acrylate), BioMed Resarch International, 2014, 102648 (2014).
    DOI:10.1155/2014/102648
  56. T. Hoshiba, M. Nikaido, M. Tanaka, Characterization of the Attachment Mechanisms of Tissue-Derived Cell Lines to Blood-Compatible Polymers, Adv. Healthcare Mater., 3, 775-784 (2014).
    DOI:10.1002/adhm.201300309
  57. H. Choi, M. Tanaka, T. Hiragun, M. Hide, K. Sugimoto, Non-tumor mast cells cultured in vitro on a honeycomb-like structured film prpliferate with multinucleateaed formation, Nanomedicine, 10, 313-319 (2014).
    DOI:10.1016/j.nano.2013.08.011
  58. J.O. Eniwumide, M.Tanaka, N. Nagai, Y. Morita, J.De Bruijn , S. Yamamoto, S. Onodera, E. Kondo, K. Yasuda, M. Shimomura. The Morphology and Functions of Articular Chondrocytes on a Honeycomb-Patterned Surface, BioMed Research International, 2014, 710354 (2014).
    DOI:10.1155/2014/710354

    2013

  59. M. Birch, M. Tanaka, G. Kirmizidis, S. Yamamoto, M. Shimomura, Microporous "Honeycomb" Films Support Enhanced Bone Formation in Vitro Tissue Engineering A, 19, 2087-2096, 2013.
    DOI:10.1089/ten.TEA.2012.0729
  60. T. Hoshiba, M. Tanaka, Breast cancer cell behaviors on staged tumorigenesis-mimicking matrices derived from tumor cells at various malignant stages, Biochemical and Biophysical Research Communications, 439, 291-296, 2013.
    DOI:10.1016/j.bbrc.2013.08.038
  61. M. Tanaka, T. Hayashi, S. Morita, The roles of water molecule at the biointerface of medical polymers, Polym. J., 45, 701-710, 2013. (Invited paper: SPSJ Asahi Kasei Award).
    DOI:10.1038/pj.2012.229

    2012

  62. T. Hayashi, Y. Tanaka, Y. Koide, M. Tanaka, M. Hara, Mechanism Underlying Bioinertness of Self-assembled Monolayers of Oligo(ethyleneglycol)-terminated Alkanethiols on Gold: Protein Adsorption, Platelet Adhesion, and Surface Forces, Physical Chemistry Chemical Physics, 14,10194-10206, 2012.
    DOI:10.1039/c2cp41236e
  63. I. Javakhishvili, M. Tanaka, K. Ogura, K. Jankova, S. Hvilsted, Synthesis of graft copolymers based on poly(2-methoxyethyl acrylate) and investigation of the associated water structure, Macromol. Rapid Commun., 33, 319-325, 2012.
    DOI:10.1002/marc.201100698
  64. T. Hatakeyama, A. Kishi, M. Tanaka, Comparison of measurement techniques for the identification of bound water restrained by polymers, Thermochim Acta, 532, 159-163, 2012.
    DOI:10.1016/j.tca.2011.01.027

    2011

  65. M. Tanaka, Design of Novel 2D and 3D Bio-Interfaces using Self-Organization to Control Cell behavior, Nanotechnologies: Emerging Applications in Biomedicine, Biochimica et Biophysica Acta (BBA) - General Subjects, 1810, 251-258, 2011.
    DOI:10.1016/j.bbagen.2010.10.002
  66. T. Hirata, H. Matsuno, M. Tanaka, K. Tanaka, Surface Segregation of Poly(2-methoxyethyl acrylate) in a Mixture with Poly(methyl methacrylate), Physical Chemistry Chemical Physics, 13, 4928-4934, 2011.
    DOI:10.1039/c0cp02101f
  67. Y. Miwa, M. Tanaka, A. Mochizuki, Analyses of Water structures and dynamics of swollen blood compatible polymers, Koubunshi Ronbunshu, 68, 133-146, 2011.
    DOI:10.1295/koron.68.133

    2010

  68. M. Tanaka, A. Mochizuki, Clarification of the Blood Compatibility Mechanism by Controlling the Water Structure at the Blood–Poly(meth)acrylate Interface, J. Biomat. Sci. Polym. Ed., 21, 1849-1863, 2010.
    DOI:10.1163/092050610X517220
  69. T. Sato, M. Tanaka, S. Yamamoto, E. Ito, K. Shimizu, Y. Igarashi, M. Shimomura, J. Inokuchi, Effect of Honeycomb-Patterned Surface Topography on the Function of Mesenteric Adipocytes, J. Biomat. Sci. Polym. Ed., 21, 1947-1956, 2010.
    DOI:10.1163/092050610X500615
  70. S. Morita, M. Tanaka, K. Kitagawa, Y. Ozaki, Hydration structure of poly(2-methoxyethyl acrylate): comparison with a 2-methoxyethyl acetate model monomer, J. Biomat. Sci. Polym. Ed., 21, 1925-1935, 2010.
    DOI:10.1163/092050610x494613
  71. Y. Miwa, H. Ishida, M. Tanaka, A. Mochizuki, 2H-NMR and 13C-NMR Study of the Hydration Behavior of Poly(2-methoxyethyl acrylate), Poly(2-hydroxyethyl methacrylate) and Poly(tetrahydrofurfuryl acrylate) in Relation to Their Blood Compatibility as Biomaterials, J. Biomat. Sci. Polym. Ed., 21, 1911-1924, 2010.
    DOI:10.1163/092050610X489682
  72. T. Hatakayama, M. Tanaka, H. Hatakayama, Thermal Properties of Freezing Bound Water Restrained by Polysaccharides, J. Biomat. Sci. Polym. Ed., 21, 1865-1880, 2010.
    DOI:10.1163/092050610X486946
  73. A. Mochizuki, M. Kimura, A. Ina, Y. Tomono, M.Tanaka, Study on water structure and blood compatibility of poly(acryloylmorpholine-r-butyl methacrylate), J. Biomat. Sci. Polym. Ed., 21, 1895-1910, 2010.
    DOI:10.1163/092050610X489321
  74. T. Hatakayama, M. Tanaka, H. Hatakayama, Studies on bound water restrained by poly(2-methacryloyloxyethyl phosphorylcholine) (PMPC): Comparison of the polysaccharides-water systems, Acta Biomaterialia, 6, 2077-2082, 2010.
    DOI:10.1016/j.actbio.2009.12.018
  75. H. Ishihata, M. Tanaka, N. Iwama, M. Ara, M. Shimonishi, M. Nagamine, N. Murakami, S. Kanaya, E. Nemoto, H. Shimauchi, M. Shimomura, Proliferation of periodontal ligament cells on biodegradable honeycomb film scaffold with unified micropore organization, Journal of Biomechanical Science and Engineering, Special Issue on Micro and Nanobiotechnology for Cells, 5, 252-261, 2010.
    DOI:10.1299/jbse.5.252
  76. Y. Uraki, C. Matsumoto, T. Hirai, Y. Tamai, M. Enoki, H. Yabu, M. Tanaka, M. Shimomura, Mechanical effect of acetic acid lignin adsorption on honeycomb-patterned cellulosic films, Journal of Wood Chemistry and Technology, 30, 348-359, 2010.
    DOI:10.1080/02773811003746709

    2009

  77. M. Tanaka, M. Takebayashi, M. Shimomura, Fabrication of ordered arrays of biodegradable polymer pincushions using self-organized honeycomb-patterned film, Macromol .Symp., (Invited original paper). 279, 175-182, 2009.
    DOI:10.1002/masy.200950527
  78. M. Tanaka, H. Sato, Y. Sasaya, S. Horinouchi, J. Hotta, Y. Matsuo, K. Ijiro, K. Sasaki, M. Shimomura, Fabrication of Novel Biocompatible Surfaces by Two-Photon Absorption Technique Using Femtosecond Laser, Mol. Cryst. Liq. Cryst., 505, 219-230, 2009.
    DOI:10.1080/15421400902950121
  79. Y. Miwa, H.Ishida, H.Saitô, M. Tanaka, A. Mochizuki, Network structures and dynamics of dry and swollen poly(acrylate)s. Characterization of high- and low-frequency motions as revealed by suppressed or recovered intensities (SRI) analysis of 13C NMR, Polymer, 50, 6091- 6099, 2009.
    DOI:10.1016/j.polymer.2009.10.037
  80. A. Mochizuki, T. Hatakeyama, Y. Tomono, M. Tanaka, Water structure and blood compatibility of poly(tetrahydrofurfuryl acrylate). J. Biomat. Sci. Polym. Ed., 20, 591-603, 2009.
    DOI:10.1163/156856209x426411
  81. A. Mochizuki, A. Kishi, M. Tanaka, Comparative study on water structures in polyHEMA and polyMEA by XRD-DSC simultaneous measurement, J. Appl. Poly. Sci., 111, 476-481, 2009.
    DOI:10.1002/app.29127
  82. Y. M. Chen, J. P. Gong, M. Tanaka, K. Yasuda, S. Yamamoto, M. Shimomura, Y. Osada, Tuning of cell proliferation on tough gels by critical charge effect, J. Biomed. Mater. Res. A, 88A, 74-83, 2009.
    DOI:10.1002/jbm.a.31869
  83. S. Tada, C. Inaba, K. Mizukami, S. Fujishita, M. Gemmei-Ide, H. Kitano, A. Mochizuki, M. Tanaka, T. Matsunaga, Anti-Biofouling Properties of Polymers with a Carboxybetaine Moiety. Macromolecular Bioscience, 9(1), 63-70, 2009.
    DOI:10.1002/mabi.200800150

    2008

  84. M. Tanaka, K. Yoshizawa, A. Tsuruma, H. Sunami, S. Yamamoto, M. Shimomura, Formation of hydroxyapatite on a self-organized 3D honeycomb-patterned biodegradable polymer film, Colloids and Surfaces A: Physicochemical and Engineering Aspects, 313-314, 515-519, 2008.
    DOI:10.1016/j.colsurfa.2007.05.081
  85. K Arai, M. Tanaka, S. Yamamoto, M. Shimomura, Effect of pore size of honeycomb films on the morphology, adhesion and cytoskeletal organization of cardiac myocytes, Colloids and Surfaces A: Physicochemical and Engineering Aspects, 313-314, 530-535, 2008.
    DOI:10.1016/j.colsurfa.2007.04.128
  86. A. Tsuruma, M. Tanaka, S. Yamamoto, M. Shimomura, Control of neural stem cell differentiation on honeycomb films, Colloids and Surfaces A: Physicochemical and Engineering Aspects, 313-314, 536-540, 2008.
    DOI:10.1016/j.colsurfa.2007.05.079
  87. A. Tanabe, S. Morita, M. Tanaka, I. Noda, Y. Ozaki, Multivariate Curve Resolution Analysis on Multi-Component Water Sorption Process into a Poly(2-methoxyethyl acrylate) Film, Appl. Spec., 62, 46-50, 2008.
    DOI:10.1366/000370208783412555
  88. H. Kitano, K. Nagaoka, S. Tada, M. Gemmei-Ide, M. Tanaka, Structure of Water Incorporated in Amphoteric Polymer Thin Films as Revealed by FT-IR Spectroscopy, Macromolecular Bioscience, 8, 77-85, 2008.
    DOI:10.1002/mabi.200700082
  89. Y. Fukuhira, M. Ito, H. Kaneko, Y. Sumi, M. Tanaka, S. Yamamoto, M. Shimomura, Prevention of postoperative adhesions by honeycomb-patterned poly(lactide)film in rat experimental model, J. Biomed. Mater. Res. B, 86B, 353-359, 2008.
    DOI:10.1002/jbm.b.31026
  90. A. Nogami, E. Tominaga, Y. Sawa, T. Murata, Y. Kudo, M.Tanaka, M.Shimomura, Development of the honeycomb film filter for individual aerosol particle analysis, Earozoru Kenkyu, 23(2), 127-133, 2008.
    DOI:10.11203/jar.23.127
  91. S. Tsukiyama, M. Matsushita, M. Tanaka, H. Tamura, S. Todo, S. Yamamoto, M. Shimomura, Enhanced cell survival and yield of rat small hepatocytes by honeycomb-patterned films, Jp. J. Appl. Phys., Vol. 47, No. 2, 1429-1434, 2008.
    DOI:10.1143/JJAP.47.1429
  92. Y. Fukuhira, H. Kaneko, M. Yamaga, M. Tanaka, S. Yamamoto, M. Shimomura, Effect of honeycomb-patterned structure on chondrocyte behavior in vitro, Colloids and Surfaces A: Physicochemical and Engineering Aspects, 313-314, 520-525, 2008.
    DOI:10.1016/j.colsurfa.2007.05.047

    2007

  93. M. Tanaka, A. Takayama, E. Ito, H. Sunami, S. Yamamoto M. Shimomura, Effect of pore size of self-organized honeycomb-patterned polymer films on spreading, focal adhesion, proliferation, and function of endothelial cells, J. Nanosci. Nanotech., 7, 763-772, 2007.
    DOI:10.1166/jnn.2007.514
  94. S. Yamamoto, M. Tanaka, E. Ito, Y. Morita , H. Sunami, K. Ijiro, M. Shimomura, The influence of pore size of a honeycomb film on early spreading process of endtherial cells, J. Surf. Sci. Soc. Jap., 28(8), 433-439, 2007.
    DOI:10.1380/jsssj.28.433
  95. T. Okajima, M. Tanaka, S. Tsukiyama, T. Kadowaki, S. Yamamoto, M. Shimomura, H. Tokumoto, Stress Relaxation and Fluctuation of Living Cells Measured by Atomic Force Microscopy, Jp. J. Appl. Phys., 46 (8B), 5552-5555, 2007.
    DOI:10.1143/JJAP.46.5552
  96. S. Yamamoto, M. Tanaka, H. Sunami, S. Yamashita, Y. Morita, M. Shimomura, Effects of honeycomb-patterned surface topography on the adhesion and signal transduction of porcine aortic endothelial cells, Langmuir, 23, 8114-8120, 2007.
    DOI:10.1021/la700332610.1021/la7003326
  97. J.R. McMillan, M. Akiyama, M. Tanaka, S. Yamamoto, M. Goto, R. Abe, D. Sawamura, M. Shimomura, H. Shimizu, Small-diameter porous poly (epsilon-caprolactone) films enhance adhesion and growth of human cultured epidermal keratinocyte and dermal fibroblast cells., Tissue Engineering, 13, 789-798, 2007.
    DOI:10.1089/ten.2006.0321
  98. Y. M. Chen, M. Tanaka, JP Gong, K Yasuda, S. Yamamoto, M. Shimomura, Y. Osada, Platelet adhesion to human umbilical vein endothelial cells cultured on anionic hydrogel scaffolds, Biomaterials, 28, 1752-1760, 2007.
    DOI:10.1016/j.biomaterials.2006.12.005
  99. T. Okajima, M. Tanaka, S. Tsukiyama, T. Kadowaki, S. Yamamoto, M. Shimomura, H. Tokumoto, Stress relaxation of HepG2 cells measured by atomic force microscopy, Nanotechnology, 18, 084010-4, 2007.
    DOI:10.1088/0957-4484/18/8/084010
  100. S. Morita, M. Tanaka, Y. Ozaki, Time-Resolved In-Situ ATR-IR Observations of Water Sorption Process into a Poly(2-methoxyethyl acrylate) (PMEA) Film, Langmuir, 23, 3750-3761, 2007.
    DOI:10.1021/la0625998
  101. T. Hayashi, M. Tanaka, S. Yamamoto, M. Shimomura, M. Hara, Direct observation of biocompatibility of  PMEA(poly(2-methoxyethyl acrylate)) using Atomic Force Microscopy, Biointerphases, 2(4), 1-9 , 2007.
    DOI:10.1116/1.2794712
  102. S. Morita, M. Tanaka, I. Noda, Y. Ozaki, Phase Angle Description of Perturbation Correlation Analysis and Its Application to Time-Resolved IR Spectra, Appl. Spec.,61(8), 867-872, 2007.
    DOI:10.1366/000370207781540051
  103. E. Hirota, M. Tanaka, A. Mochizuki, Blood Compatibility and Water Structure-Comparative Study between 2-Methoxyethylacrylate- and 2-Methoxyethylmethacrylate-based random copolymers, J. Biomed. Mater. Res. 81A, 710-719, 2007.
    DOI:10.1002/jbm.a.31113
  104. Y. Uraki, J. Nemoto, H. Otsuka, Y. Tamai, J. Sugiyama, T. Kishimoto, M. Ubukata, H. Yabu, M. Tanaka, M. Shimomura, Honeycomb-Like Architecture Produced by Living Bacteria, Gluconacetobacter xylinus, Carbohydrate Polymers, 69, 1-6, 2007.
    DOI:10.1016/j.carbpol.2006.08.021
  105. T. Hatakeyma, H. Kasuga, M. Tanaka, H. Hatakeyama, Cold crystallization of poly(ethylene glcyol)-water systems, Thermochim Acta, 465, 59-66, 2007.
    DOI:10.1016/j.tca.2007.09.005

    2006

  106. S. Yamamoto, M. Tanaka, H. Sunami, S. Yamashita, Y. Morita, M. Shimomura, Relationship between adsorbed fibronectin and cell adhesion on a honeycomb-patterned film, Surf. Sci., 600, 3785-3791, 2006.
    DOI:10.1016/j.susc.2006.01.085
  107. M. Tanaka, K. Nishikawa, H. Okubo, H. Kamachi, T. Kawai, M. Matsushita, S. Todo, M. Shimomura, Control of hepatocyte adhesion and function on self-organized honeycomb-patterned polymer film, Colloids and Surfaces A: Physicochemical and Engineering Aspects, 284-285, 464-469, 2006.
    DOI:10.1016/j.colsurfa.2005.11.098
  108. A. Tsuruma, M. Tanaka, S. Yamamoto, N. Fukushima, H. Yabu, M. Shimomura, Topographical control of neurites extension on stripe-patterned polymer films, Colloids and Surfaces A: Physicochemical and Engineering Aspects, 284-285, 470-474, 2006.
    DOI:10.1016/j.colsurfa.2005.11.100
  109. S. Yamamoto, M. Tanaka, H. Sunami, S. Yamashita, Y. Morita, M. Shimomura, Relationship between Adsorbed Fibronectin and Cell Adhesion on a Honeycomb-patterned Film, J. Surf. Sci. Soc. Jap., 27(10), 2006.
    DOI:10.1380/jsssj.27.502
  110. H. Sunami, E. Ito, M. Tanaka, S.Yamamoto, M. Shimomura, Effect of honeycomb film on protein adsorption, cell adhesion and proliferation. Colloids and Surfaces A: Physicochemical and Engineering Aspects, 284-285, 548-551, 2006.
    DOI:10.1016/j.colsurfa.2005.11.041
  111. Y. Fukuhira, E. Kitazono, T. Hayashi, H. Kaneko, M. Tanaka, M. Shimomura, Y. Sumi, Biodegradable honeycomb-patterned film composed of poly(lactic acid) and dioleoylphosphatidylethanolamine, Biomaterials, 27, 1797-1802, 2006.
    DOI:10.1016/j.biomaterials.2005.10.019
  112. E. Hirota, K. Ute, M. Uehara, T. Kitayama, M. Tanaka, A. Mochizuki, -Study of Blood Compatibility with Poly(2-Methoxyethylacrylate) - Relationship between Surface Structure, Water Structure and Platelet Compatibility in 2-Methoxyethylacrylate/2-Hydroxyethylmethacrylate Diblock Copolymer, J. Biomed. Mater. Res., 76A, 540-550, 2006.
    DOI:10.1002/jbm.a.30563
  113. M. Shimomura, A. Tsuruma, M. Tanaka, H. Sunami, S. Yamamoto, Biomedical application of patterned polymer films prepared by self-organization, J. Surf. Sci. Soc. Jap., 27, 170-175, 2006.
    DOI:10.1380/jsssj.27.170

    2005

  114. A. Tsuruma, M. Tanaka, N. Fukushima, M. Shimomura, Morphological changes in neurons by self-organized patterned films, e-J. Surf. Sci. Nanotech., 3, 159-164, 2005.
    DOI:10.1380/ejssnt.2005.159
  115. H. Kitano, T. Mori, Y. Takeuchi, S. Tada, M. Gemmei-ide, Y. Yokoyama, M. Tanaka, Structure of Water Incorporated in Sulfobetaine Polymer Films as Studied by ATR-FTIR, Macromol. Biosci., 5(4), 314-321, 2005.
    DOI:10.1002/mabi.200400212
  116. J. Nemoto, Y. Uraki, T. Kishimoto, Y. Sano, R. Funada, N. Obata, H. Yabu, M. Tanaka, M. Shimomura, Production of mesoscopically patterned cellulose film, Bioresource Technol, 96(17), 1955-1958, 2005.
    DOI:10.1016/j.biortech.2005.01.034
  117. H. Kitano, S. Tada, T. Mori, K. Takaha, M. Gemmei-Ide, M. Tanaka, M. Fukuda, Y. Yokoyama, Correlation between the Structure of Water in the Vicinity of Carboxybetaine Polymers and Their Blood-Compatibility, Langmuir, 21, 11932-11940, 2005.
    DOI:10.1021/la0515571
  118. H. Yabu, M. Takebayashi, M. Tanaka, M. Shimomura, Superhydrophobic and Lipophobic Properties of Self-Organized Honeycomb and Pincushion Structures, Langmuir, 21(8), 3235-3237, 2005.
    DOI:10.1021/la050013w

    2004年以前

  119.  A. Tsuruma, M. Tanaka, N. Fukushima, M. Shimomura, Control of neurites extension by self-organized patterned polymer films, Koubunshi Ronbunshuu, 61(12), 628-633, 2004.
    [PDF]
  120. G. Li, S. Morita, S. Ye, M. Tanaka, M. Osawa, Bisphenol QCM and IRRAS Characterization of Bisphenol A Absorption in the Poly(acrylate) Thin Films, Anal. Chem.76, 788-795, 2004.
    DOI:10.1021/ac0348874
  121. M. Tanaka, A. Mochizuki, Effect of water structure on blood compatibility-Thermal analysis of water in poly(meth)acrylate-, J. Biomed. Mater. Res., 68A(3), 684-695, 2004.
    DOI:10.1002/jbm.a.20088
  122. M. Tanaka, Design of Novel BioInterfaces (I) -Blood compatibility of poly(2-methoxyethyl acrylate)-, Bio-Med. Mater. Eng., 14, 427-438, 2004.
    [HTML]
  123. M. Tanaka, M. Takebayashi, M. Miyama, J. Nishida, M. Shimomura, Design of Novel BioInterfaces (II) -Fabrication of self-organized porous polymer film with highly uniform pores-, Bio-Med. Mater. Eng., 14, 439-446, 2004.
    [HTML]
  124.  M. Ide, T. Mori, K. Ichikawa, H. Kitano, M.Tanaka, A. Mochizuki, H. Oshiyama, W. Mizuno, Structure of Water Sorbed into Poly(MEA-co-HEMA) Films As Examined by ATR-IR Spectroscopy, Langmuir, 19, 429-435, 2003.
    DOI:10.1021/la020617p
  125. M. Tanaka, Blood Compatibility of Poly(2-methoxyethyl acrylate) - Design of Novel Biointerfaces, Koubunshi Ronbunshuu, 60(8), 415-427, 2003.
    DOI:10.1295/koron.60.415
  126. S. Ye, S. Morita, G. Li, H. Noda, M. Tanaka, K. Uosaki, M. Osawa, Interfacial Molecular Structure Changes in Poly(2-methoxyethyl acrylate) Thin Films Induced by Absorption of Bisphenol A. An Infrared and Sum Frequency Generation (SFG) Study, Macromolecules, 36, 5694-5703, 2003.
    DOI:10.1021/ma026007d
  127. H. Yabu, M. Tanaka, K. Ijiro, M. Shimomura, Preparation of honeycomb patterned polyimide films by self-organization, Langmuir, 19, 6297-6300, 2003.
    DOI:10.1021/la034454w
  128. M. Tanaka, A. Mochizuki, N. Ishii, T. Motomura, T. Hatakeyama, Study of Blood Compatibility With poly(2-methoxyethyl Acrylate). Relationship Between Water Structure and Platelet Compatibility in poly(2-methoxyethylacrylate-co- 2-hydroxyethylmethacrylate), Biomacromolecules, 3, 36-41, 2002.
    DOI:10.1021/bm010072y
  129. M. Tanaka, A. Mochizuki, T. Shiroya, T. Motomura, K. Shimura, M. Onishi, Y. Okahata, Study on kinetics of early stage protein adsorption on poly(2-methoxyethylacrylate) (PMEA) surface. Colloids and Surfaces A: Physicochemical and Engineering Aspects, 203, 195-204, 2002.
    DOI:10.1016/S0927-7757(01)01100-1
  130. K. Sato, M. Tanaka, K. Hasebe, M. Takebayashi, K. Nishikawa, T. Kawai, M. Matsushita, S. Todo, M. Shimomura, Preparation of the honeycomb patterned porous film of biodegradable polymer for tissue engineering scaffolds, Inter. J. Nanosci., 1(5,6), 689-693, 2002.
    DOI:10.1142/9789812796714_0055
  131. M.Tanaka, A. Mochizuki, T. Motomura, K. Shimura, M. Onishi, Y. Okahata. In Situ Studies on Protein Adsorption onto a Poly(2-methoxyethyl acrylate) Surface by a Quartz Crystal Microbalance. Colloids and Surfaces A: Physicochemical and Engineering Aspects, 193, 145-152, 2001.
    DOI:10.1016/S0927-7757(01)00682-3
  132. H. Kitano, K. Ichikawa, M. Fukuda, A. Mochizuki, M. Tanaka, The Structure of Water Sorbed to Polymethylmethacrylate Film As Examined by FT-IR Spectroscopy, J. Colloid Surface Sci., 242, 133-140, 2001.
    DOI: 10.1006/jcis.2001.7785
  133. K. Ichikawa, T. Mori, H. Kitano, M. Fukuda, A. Mochizuki, M. Tanaka, A FT-IR Study on the Sorption of Water to Various Kinds of Polymer Thin Films, J. Polym. Sci., B Polym. Phys. 39, 2175-2182, 2001.
    DOI:10.1002/polb.1191
  134. L. Schiel, S. Burns, A. Nogawa, R. Rice, T. Anzai, M. Tanaka, X-Coating : A New Biopassive Polymer Coating, Canadian Perfusion Canadienne, 11(2), 8-17, 2001.
    [PDF]
  135. M. Tanaka, T. Motomura, N. Ishii, K. Shimura, M. Onishi, A. Mochizuki, T. Hatakeyama, Cold crystallization of water in hydrated Poly(2-methoxyethyl acrylate) (PMEA), Polymer International, 49, 1709-1713, 2000.
    DOI:10.1002/1097-0126(200012)49:12<1709::AID-PI601>3.0.CO;2-L
  136. M. Tanaka, T. Motomura, M. Kawada, T. Anzai, Y. Kasori, T. Shiroya, K. Shimura, M. Onishi, A. Mochizuki, Y. Okahata, A new blood-compatible surface prepared by Poly(2-methoxyethyl acrylate) (PMEA) coating -Protein adsorption on PMEA surface-, Jpn. J.Art. Org, 29, 209-216, 2000.
    DOI:10.11392/jsao1972.29.209
  137. M. Tanaka, T. Motomura, M. Kawada, T. Anzai, Y. Kasori, T. Shiroya, K. Shimura, M. Onishi, A. Mochizuki, Blood compatible aspects of Poly(2-methoxyethylacrylate) (PMEA) -Relationship between protein adsorption and platelet adhesion on PMEA surface-, Biomaterials, 21, 1471-1481, 2000.
    DOI:10.1016/S0142-9612(00)00031-4
  138.  M.Shimomura, F.Nakamura, K.Ijiro, H.Taketsuna, M.Tanaka, H.Nakamura, K.Hasebe, Two-dimrnsional DNA-mimetic monolayer organization at the air-water interface, J. Am. Chem. Soc., 119, 2341-2342, 1997.
    DOI:10.1021/ja962847u
  139. K.Ijiro, M.Shimomura, M.Tanaka, H.Nakamura, K.Hasebe, DNA monolayers complexed with amphiphilic intercalator at the air water interface, Thin Solid Films, 284-285, 780-783, 1996.
    DOI:10.1016/S0040-6090(95)08445-2
  140. M.Shimomura, F.Nakamura, K.Ijiro, H.Taketsuna, M.Tanaka, H.Nakamura, K.Hasebe, Chiral crystal formation of octadecylcytosine monolayer by complementary base-paring, Thin Solid Films, 284-285691-693, 1996.
    DOI:10.1016/S0040-6090(95)08422-3



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